Clinical Pharmacology and Pharmacologically Assisted Care in Obstetrics
Study Course Implementer
Department of Pharmacology and Pharmacotherapeutics, Konsula street 21, 2nd floor, room 211, Riga, LV-1007; liva.vanaga@rsu.lv, linda.rugele@rsu.lv, tel. +37167409213
About Study Course
Objective
According to the chosen specialty , to promote students' ability to orient themselves in the pharmacotherapy of the most common chronic diseases and the most characteristic complaints during pregnancy and breastfeeding. To provide knowledge of the most characteristic side effects and contraindications, taking into account the choice of the method of administration. To ensure understanding of the possibilities of using medicines necessary for the course of childbirth and potential risks. To create an idea of the use of medicines in the pediatric population.
Preliminary Knowledge
In physiology, biochemistry, pharmacology, gynaecology and obstetrics, neonatology.
Learning Outcomes
Knowledge
1.Students will be able to describe the effect of medicines on the functions of organ systems, will be able to define the basic indications, most common side effects and contraindications.
2.Students are expected to gain knowledge about the medications used in termination of pregnancy, preservation of pregnancy and delivery, their realized effect, possible side effects and risks of administration.
3.Students will be able to describe the essence of the pregnancy prevention program.
Skills
1.Be able to classify medicines according to their use in chronic diagnoses, emergency situations or pregnancy-related situations.
2.Be able to describe the purpose and risks of regularly prescribed medicines during pregnancy and lactation.
3.Describe the basic principles of pharmacotherapy of indications related to termination of pregnancy, pregnancy and delivery.
4.Be able to differentiate the risks associated with the use and administration of medicines according to their severity.
5.Be able to calculate the dose to be administered according to the prescription.
6.Be able to evaluate the risks of teratogenicity and breast-feeding according to officially available information.
Competences
1.Be able to recommend medicines to alleviate complaints typical of pregnancy.
2.Be able to educate patients about the correct use of medicines, their indications and adverse effects.
3.Be able to explain the purpose and therapeutic effectiveness of medicines in terms understandable to the patient.
4.As a result of multidisciplinary cooperation, according to professional specifics, will be able to participate in the evaluation of pharmacotherapy and the introduction of corrections.
5.Will be able to analyse the medicines indicated in the anamnesis and orders according to the expected clinical effect, will be able to assess their therapeutic effectiveness and the development of side effects in the work environment.
6.Promote the reduction of the risk of medication errors and inappropriate prescription.
Assessment
Individual work
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Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
Test
|
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Analysis of the prescriptions received and fulfilled during the clinical practice according to the requirements of the report protocol (placed in E-studies). The form of submission of the work done (electronically or in paper format) is done by mutual agreement between the lecturer and the students. The protocol is submitted within the specified deadline before the individual interview. Submission of the protocol is mandatory. The independent work is evaluated with a test. |
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Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Colloquia I |
50.00% from total grade
|
10 points
|
|
30-question examination consisting of multiple-choice questions, clinical case studies and calculation tasks in varying proportions. |
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|
2.
Colloquium II |
50.00% from total grade
|
10 points
|
|
30-question examination consisting of multiple-choice questions, clinical case studies and calculation tasks in varying proportions. |
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|
3.
Individual interviews |
-
|
Test
|
|
At the end of the study course, on the scheduled dates, each student must have an individual interview with the lecturer, during which feedback is given on the course and an analysis of the independent work is carried out. The interview is a mandatory event, without which the student cannot obtain a positive final assessment in the course. |
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4.
Examination |
-
|
-
|
|
The accumulated exam assessment is awarded in the study course regardless of the value obtained, but the condition of individual discussions with the course lecturer is mandatory. The final assessment is calculated as the average grade from both mid-semester examinations taken during the semester. |
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Study Course Theme Plan
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Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Antihypertensive therapy in pregnancy.
|
|
Antithrombotic and hypolipidaemic therapy during pregnancy.
|
|
Antianginal and antiarrhythmic agents.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Principles of asthma therapy during pregnancy.
|
|
Use of anti-allergy medicines during pregnancy.
|
|
Respiratory infection treatment in pregnancy.
|
|
Management of anaphylactic shock during pregnancy.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Treatment of gastroesophageal reflux during pregnancy.
|
|
Management of pregnancy toxicosis.
|
|
Options for preventing constipation and hemorrhoids during pregnancy.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Medications used in the treatment of type 1 diabetes. Treatment options for gestational diabetes.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Pain management during pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Antihypertensive therapy in pregnancy.
|
|
Antithrombotic and hypolipidaemic therapy during pregnancy.
|
|
Antianginal and antiarrhythmic agents.
|
|
Basic principles of heart failure management.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Principles of asthma therapy during pregnancy.
|
|
Use of anti-allergy medicines during pregnancy.
|
|
Respiratory infection treatment in pregnancy.
|
|
Management of anaphylactic shock during pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Treatment of gastroesophageal reflux during pregnancy.
|
|
Management of pregnancy toxicosis.
|
|
Options for preventing constipation and hemorrhoids during pregnancy.
|
|
Treatment options for gastroenteritis in pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Medications used in the treatment of type 1 diabetes. Treatment options for gestational diabetes.
|
|
Drugs for the treatment of type 2 diabetes.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Guideline-based wound care solutions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Computer room
|
2
|
Topics
|
Colloquium 1: Therapeutic options for cardiovascular diseases, respiratory diseases, gastrointestinal diseases and diabetes.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Pain management during pregnancy.
|
|
Management of autoimmune conditions in pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Treatment options for urinary tract infection and nephritis in pregnancy.
|
|
Management of bacterial vaginosis and candidiasis in pregnancy.
|
|
Antimicrobial therapy for sexually transmitted infections in pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Pharmacological treatment of infertility.
|
|
Prevention of preterm birth.
|
|
Medications used in childbirth.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Prevention and termination of unwanted pregnancy.
|
|
Management of Emergencies in Pregnancy.
|
|
Teratogenic drugs. Pregnancy prevention program.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Computer room
|
2
|
Topics
|
Colloquium 2: Management of urogenital diseases and pain management during pregnancy. Prevention of premature birth. Drugs used during childbirth. Medical abortion.
|
Bibliography
Required Reading
Ainsworth, Sean B. Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life. John Wiley & Sons, Incorporated, 2014. ProQuest Ebook CentralSuitable for English stream
Rebar, Cherie R., et al. Pharmacology Made Incredibly Easy, Wolters Kluwer, 2022. ProQuest Ebook CentralSuitable for English stream
Briggs, Gerald G; Freeman, Roger K; Yaffe, Sumner J. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Lippincott Williams & Wilkins, 2011, 1728 p. (akceptējams izdevums)Suitable for English stream
Basic & Clinical Pharmacology. Bertram G. Katzung. McGraw-Hill Professional, 2021, 1179 lpp.Suitable for English stream
Lekciju materiāls RSU E-studijas
Additional Reading
Ford, Susan M. Roach's introductory clinical pharmacology / Susan M. Ford, Sally S. Roach. 9th ed. Philadelphia : Wolters Kluwer Health/Lippincott Williams & Wilkins, c2010
Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. edited by Christof Schaefer, et al. Elsevier Science & Technology, 2007. ProQuest Ebook Central
Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 14th Ed. Laurence L. Brunton, et al. New York: McGraw-Hill, 2022
Barbara G Wells. Pharmacotherapy Handbook. McGraw-Hill Professional, 2021
British National Formulary. BNF 2019
Dzemdniecība. Daces Rezebergas redakcijā. Medicīnas apgāds, 2016, 448 lpp.
Other Information Sources
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