Veidlapa Nr. M-3 (8)

Study Course Description

Hospital Paediatrics with Consultative Outpatient Work, Including Outpatient Paediatrics/Transfusiology

Main Study Course Information

Course Code

RBH_032

Branch of Science

Anaesthesiology and Resuscitation; Clinical medicine

ECTS

6.00

Target Audience

Medicine

LQF

Level 8

Study Course Implementer

Course Supervisor

Žanna Kovaļova

Residency Speciality

Speciality

Pediatric oncohematologist

Supervisor of Medical Speciality

Žanna Kovaļova

Contacts

About Study Course

Objective

Assure theoretical knowledge and practical skills acquisition in transfusiology.

Learning Outcomes

Knowledge

1.Use of knowledge about principles of replacement haemocomponent therapy in patients of any age, newborn transfusiology principles, specific requirement for blood components in of neonatal transfusiology. List indications for blood products in case of different transfusion policy.

Skills

1.Determining of blood group and rhesus, determining of HLA antigens, principles of therapeutic cytapheresis, to participate in the performance of cytapheresis procedures.

Competences

1.Students must master the requirements for selection of donors, to know transfusion reactions, to learn the ABO and HLA system, to learn the requirements for blood components in paediatric haematology, their relatives, to collect necessary information – patient history.

Assessment

Individual work

Title	% from total grade	Grade
1. Individual work	-	-
Preparation of a presentation.

Examination

Title	% from total grade	Grade
1. Examination	-	-
After each module (rotation cycle) medical resident’s theoretical and practical knowledge is assessed in a 10-point grade system by the medical resident's supervisor of the rotation cycle by making a respective record in the medical resident’s book.

Study Course Theme Plan

FULL-TIME

Part 1

Seminar

Modality	Location
On site	Auditorium

Topics

Blood transfusion methods. Selection of donors. Preparation, conditions of storage and transportation of blood components. Therapeutic plasmapheresis and cytapheresis. Application in paediatric onco-haematology. Transfusion reactions – classification, aetiology, pathogenesis, clinic, treatment, prevention.

Seminar

Modality	Location
On site	Auditorium

Topics

ABO system, genetics. Determination of blood groups in the ABO system with forward and reverse reaction. Sub-groups, extraagglutinins and their clinical significance. Immune agglutinins anti – A and anti – B. Errors and potential problems, when performing forward and reverse reaction. Acquired B antigen. Donor and recipient blood compatibility tests.

Seminar

Modality	Location
On site	Auditorium

Topics

Immunological relationship between the mother and the foetus. Haemolytic disease of the new-born, prevention and anti Rh (D) immunoglobulin. Rhesus antigen system, characteristics of antigens, tests to determine rhesus compatibility. Potential errors in determining D antigen. Haemolytic anaemias caused by antibodies. Cold haemagglutinin disease and paroxysmal cold haemoglobinuria.

Total ECTS (Creditpoints):

6.00

Number of Residency Seminars:

Length (weeks):

Final Examination:

Residency exam (Theory and practice)

Bibliography

Required Reading

Practical Transfusion Medicine. Michael F. Murphy, Derwood H. Pamphilon, and Nancy M. Heddle. 2022, 578 lpp (ebook central)

Blood Guide. 20th Edition of the Guide to the preparation, use and quality assurance of blood components

Essential Guide to Blood Groups. 3rd Edition. 2013. Geoff Daniels and Imelda Bromilow. 133 lpp. (ebook central) (akceptējams izdevums)

27.12.2005. MK noteikumu Nr. 1037 „Noteikumi par cilvēka asiņu un asins komponentu savākšanas, testēšanas, apstrādes, uzglabāšanas un izplatīšanas kvalitātes un drošības standartiem, ievešanas un izvešanas nosacījumiem, kā arī kompensāciju par izdevumiem zaudētā asins apjoma atjaunošanai”

"Transfūzijas medicīnas tehnoloģijas" (medicīnisko tehnoloģiju datu bāze).

Lejniece S. Klīniskā hematoloģija. Rīga: Medicīnas apgāds, 2020. latv.-439.lpp

Paula R. Howard. Basic & Applied Concepts of Blood Banking and Transfusion Practices. 5th Edition. Elsevier, 2025, 420 lpp.

Robert W. Maitta. Immunologic Concepts in Transfusion Medicine. Elseiver, 2020, 367 lpp.

Milenko Jovan Tanasijevic. Topics in pediatric transfusion medicine. Elseiver, 2021, 171 lpp.

10.

George P. Canellos, H. Franklin Bunn. Transfusion medicine. Elseiver, October 2019, Volume 33, Number 5

11.

A. Lejnieka red. Kliniskā medicīna. trešā grāmata. Medicīnas apgāds, 2012, 537 lpp. (akceptējams izdevums)

12.

Johns, Gockel-Blessing, Zundel, Denesiuk. Clinical Laboratory Blood banking and Transfusion Medicine. Principles and Practice, Pearson, 2015, 455 lpp.

13.

Mark T. Friedman, Kamille A. West, Peyman Bizargity. Immunohematology and Transfusion Medicine. A case stude Approach. Springer, 2023, 180 lpp.

14.

Marion E. Reid, Christine Lomas-Francis and Martin L. Olsson. The Blood group antigen. 3rd Edition. 2012, 731 lpp. (akceptējams izdevums)