Veidlapa Nr. M-3 (8)
Study Course Description
Medical Biochemistry
Course Code
CFUBK_068
Branch of Science
Chemical sciences
ECTS
3.00
Target Audience
Public Health
LQF
Level 6
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Irina Kazuša
Structure Unit Manager
Pēteris Tretjakovs
Structural Unit
Department of Human Physiology and Biochemistry
Contacts
Riga, 16 Dzirciema Street, cfbk@rsu.lv, +371 67061550
About Study Course
Objective
Course objective is to promote the acquisition of knowledge not only about chemical reactions, but also on certain biochemical processes in life-providing processes in the context of the transformation and the development of practical work experience for students, and to build an idea about the analytical results of the statistical processing.
Preliminary Knowledge
Chemistry, Physics, Biology.
Learning Outcomes
Knowledge
1.The student knows the life processes of transformation-providing chemical and biochemical reactions, fundamental principles, the operating conditions and consequences.
Skills
1.The student is able to justify the chemical and biochemical methods in use and has acquired the skills to independently carry out those laboratory methods to qualitatively and quantitatively determine analytes in different samples. The student is able to analyse the data obtained with laboratory methods, including his own findings; is able to adequately process and to make consequential and reasoned conclusions about laboratory detected analytes' relationship with metabolic processes in the body.
Competences
1.Based on the theoretical knowledge of the facts, the student is able to: • describe the reaction's energetic and kinetic parameters (enthalpy, entropy, Gibbs energy, concentration, reaction time); • outline the biochemical processes and the development in the conditions, eg., hydrolysis of nutrients in the digestive tract, biomolecule structure and functions; • explain carbohydrate, lipid and protein synthesis reactions and the importance of their implementation.
Assessment
Individual work
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Individual work |
-
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-
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Compiliation of chemical reaction equations, problem solving and calculation of the concentrations, studies of literature, material acquisition from e-studies.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
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Examination
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Examination |
-
|
-
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Tests during the study course, written theoretical exam (multiple-choice test).
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Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
|
2
|
Topics
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Energy transformation in biochemical processes. The law of Energy Conservation. Catabolism and anabolism.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
|
Auditorium
|
2
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Topics
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Homeostasis-providing processes: electrolytic dissociation, concentration alignment in solutions, pH unchangeability, balance response direction adjustment.
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-
Lecture
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
2
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Topics
|
Introduction to biochemistry. Functional groups in molecules of organic matter.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
|
Auditorium
|
2
|
Topics
|
Biochemically significant carbohydrates.
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-
Lecture
|
Modality
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Location
|
Contact hours
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|---|---|---|
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On site
|
Auditorium
|
2
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Topics
|
Biochemically significant lipids.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
2
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Topics
|
Simple and composite protein characterisation.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
|
2
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Topics
|
Enzyme mechanism of action and specificity.
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-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Catabolism and anabolism of carbohydrates, lipids, proteins.
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-
Class/Seminar
|
Modality
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Location
|
Contact hours
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|---|---|---|
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On site
|
Laboratory
|
2
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Topics
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Workshop:
Basic methods of analytical chemistry. Concentration calculations.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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2
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Topics
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Laboratory work "Acid-base titration".
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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2
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Topics
|
Colloquium:
Processes providing homeostasis, colligative properties of solutions, electrolytic dissociation. Concentration and calculation of osmotic pressure in solutions.
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-
Class/Seminar
|
Modality
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Location
|
Contact hours
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|---|---|---|
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On site
|
Laboratory
|
2
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Topics
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Seminar:
Laboratory work. Characteristics of carbohydrate molecules. Carbohydrate digestion.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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2
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Topics
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Seminar:
The structure of lipid molecules. Lipid and fat digestion.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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2
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Topics
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Seminar:
Design of simple and composite protein molecules.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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2
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Topics
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Laboratory Work "Amiloclastic Power".
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
|
Laboratory
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2
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Topics
|
Colloquium:
Catabolism and anabolism of carbohydrates, lipids, proteins.
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Total ECTS (Creditpoints):
3.00
Contact hours:
32 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
A.Rauhvargers. „Vispārīgā ķīmija”. Rīga, 1996 (akceptējams izdevums)
Additional Reading
1.
RSU e-studiju materiāli
2.
D. Cēdere, J. Logins. „Organiskā ķīmija ar ievirzi bioķīmijā”. Zvaigzne ABC, 1996
Other Information Sources
1.
Nelson, Cox, Lehninger, Cox, Michael M, & Lehninger, Albert L. Lehninger principles of biochemistry / David L. Nelson, Professor Emeritus of Biochemistry, University of Wisconsin-Madison, Michael M. Cox Professor of Biochemistry, University, 2017
2.
Lippincotts Illustrated Reviews: Biochemistry, 2010