Veidlapa Nr. M-3 (8)
Study Course Description
Transfusion Medicine and Immunohaematology
Course Code
RHE_047
Branch of Science
Anatomy; Clinical medicine
ECTS
6.00
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Sandra Lejniece
Residency Speciality
Speciality
Hematologist
Supervisor of Medical Speciality
Sandra Lejniece
Contacts
-
About Study Course
Objective
To ensure acquisition and improvement of theoretical knowledge and practical skills in transfusion medicine and immunohaematology according to the requirements of the Regulation of the Haematology specialty in order to prepare a physician for certification in the specialty of haematology.
Learning Outcomes
Knowledge
1.A resident will have knowledge of the principles of blood banks, haemovigilance standards; will have knowledge of the principles of the organisation of the donor movement.
Skills
1.Upon completion of the study programme, the resident will be able to assess the indications regarding transfusion of blood preparations, determine the indications for the use of irradiated blood components and CMV-negative blood components. The student will be able to assess the indications for blood compatibility in a special immunohaematology laboratory.
Competences
1.To understand principles and contraindications for donor selection; To participate in donor selection and examine donors; To participate in thrombocyte apheresis procedures, observe a donor during the procedure; To acquaint oneself with the immunohaematology laboratory; To acquaint oneself with the HLA-typing laboratory.
Assessment
Individual work
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Title
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% from total grade
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Grade
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1.
Individual work |
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-
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1. Independently studies literature related to the course topics;
2. Independently prepares for seminars;
3. Reads and analyses medical documents;
4. Completes medical records;
5. Independently follows the instructions of the certified specialist.
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Examination
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Examination |
-
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-
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Compulsory attendance of seminars (100%) and practical work (100%) in each study course.
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Study Course Theme Plan
FULL-TIME
Part 1
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Seminar
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Modality
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Location
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On site
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Auditorium
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Topics
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European Union and Latvian laws and regulations governing transfusion. Principles of donor selection, donor observation and potential complications. Preparation, safety and storage of standard and special blood components (blood, erythrocyte mass, thrombocyte mass, plasma, cryoprecipitate, irradiated, washed and pathogen-reduced components).
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Seminar
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Modality
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Location
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On site
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Auditorium
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Topics
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Immunohaematology problems: compatibility standards, direct and indirect Coombs test, ABO and Resus factor types in red cells. Small antigens and antibodies of red cells.
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Seminar
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Modality
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Location
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On site
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Auditorium
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Topics
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Recommendations and regulations governing the transfusion of blood and blood components. Indications for transfusion of erythrocyte mass, thrombocyte mass, plasma, intravenous immunoglobulins. Alternatives to allogeneic blood transfusion. Massive transfusions (surgery, trauma, pregnancy).
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Total ECTS (Creditpoints):
6.00
Number of Residency Seminars:
3
Length (weeks):
4
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Guide to the preparation, use and quality assurance of blood components. 20th ed. Council of Europe, 2020.
2.
Robert W. Maitta Clinical Principles of Transfusion Medicines, Elsevier 2018.
3.
Michael F. Murphy, David J. Roberts and MarkH. Yazer Practical Transfusion medicine. 5th ed. Wiley Blackwell 2017.
4.
Denise M. Harmening Modern blood banking&Transfusion Practices, 7th ed. F. A. Davis Company, 2018.
5.
Liepiņš M., Lejnieks A. Rekomendācijas empīriskai un etiotropai antimikrobiālai ārstēšanai. 4. redakcija. Aslimnīca, 2020.
6.
Lejniece S. Klīniskā hematoloģija. Rīga: SIA medicīnas apgāds, 2020.
7.
The EBMT Handbook. Hematopoietic Stem Cell Transplantation and Cellular Therapies. 7th edition. Ed. by Carreras E., Dufour C., Mohty M., Kroger N. Springer International Publishing, 2019.
8.
John P. Greer MD, Daniel A. Arber MD, Bertil E. Glader MD, et al. Wintrobe’s Clinical Hematology. 14th edition. Lippincott, William & Wilkins, 2018.
9.
Abbas A. K., Lichtman A. H., Shiv P. Basic Immunology: Functions and Disorders of the Immune System. 6th edition. Elsevier, 2019.
10.
Male D., Brostoff J., Roth D. B., Roitt I. Immunology. 8th edition. Saunders, 2012.
11.
Turgeon M. L. Immunology and serology in Laboratory Medicine. 6th edition. Elsevier, 2017.
Additional Reading
1.
Daniels G., Bromilow I. Essential Guide to Blood Groups. Oxford: Blackwell; 2009.
2.
Ņemceva G., Sisene I., Šteinerte A. Praktiskā transfuzioloģija. Rīga: Medicīnas apgāds; 2009.
3.
Quinley E. D., Immunohematology. Principles & Practice. 3rd ed.- Lippincot Williams&Wilkins, 2011.
Other Information Sources
1.
27.02.2018. MK noteikumu Nr. 1037 „Noteikumi par cilvēka asiņu un asins komponentu savākšanas, testēšanas, apstrādes, uzglabāšanas un izplatīšanas kvalitātes un drošības standartiem un kompensāciju par izdevumiem zaudētā asins apjoma atjaunošanai”
2.
LVS EN ISO/IEC 17025:2017 “Testēšanas un kalibrēšanas laboratoriju kompetences vispārīgās prasības”
3.
LVS EN ISO 15189:2013 “Medicīnas laboratorijas. Kvalitātes un kompetences prasības”
4.
Eiropas Parlamenta un Padomes Direktīvu 2002/98/EK (2003.gada 27. janvāris), ar kuru nosaka kvalitātes un drošības standartus attiecībā uz cilvēka asins un asins komponentu savākšanu, testēšanu, apstrādi, uzglabāšanu un izplatīšanu, kā arī groza Direktīvu 2001/83/EK
5.
Komisijas Direktīvas 2016/62/EK (2016. gada 25. jūlijs) par Eiropas Parlamenta un Padomes Direktīvas 2005/62/EK piemērošanu attiecībā uz Kopienas standartiem un specifikācijām, kas attiecas uz asins sagatavotāju kvalitātes sistēmu
6.
Komisijas Direktīvas 2005/61/EK (2005. gada 30. septembris), ar ko īsteno Eiropas Parlamenta un Padomes Direktīvu 2002/98/EK attiecībā uz izsekojamības prasībām un nopietnu blakņu un nevēlamu notikumu paziņošanu
7.
Komisijas Direktīvas 2003/94/EK (2003. gada 8. oktobris), ar ko nosaka labas ražošanas prakses principus un pamatnostādnes attiecībā uz cilvēkiem paredzētām zālēm un pētāmām cilvēkiem paredzētām zālēm
8.
Komisijas Direktīva 2004/33/EK (2004. gada 22. marts) par Eiropas Parlamenta un Padomes Direktīvas 2002/98/EK piemērošanu attiecībā uz dažām tehniskajām prasībām asinīm un asins komponentiem