Veidlapa Nr. M-3 (8)
Study Course Description
Laboratory Work in Specialised Medical Centres and Multiprofile Hospitals
Course Code
RLA_016
Branch of Science
Clinical medicine; Health care sciences and services
ECTS
25.95
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Jeļena Storoženko
Residency Speciality
Speciality
Laboratory doctor
Supervisor of Medical Speciality
Jeļena Storoženko
Contacts
-
About Study Course
Objective
To prepare laboratory doctors for work in laboratories in specialised medical centres and multiprofile hospitals. To obtain knowledge about the specifics of laboratory work organisation in emergency medical assistance structures, in children’s health care institutions, in the laboratory of infectious diseases, as well as organisation of the work of an accredited laboratory. To use laboratory information systems in daily practice of a laboratory, incl. for preparation of testing results and drawing up of testing reports. To obtain knowledge about advantages of choosing examination methods in multiprofile hospital laboratories, interpretation of obtained results, procedure of notification of critical values of indicators and selection of further examination tactics.
Learning Outcomes
Knowledge
1.- to describe stages of operation of a multiprofile hospital laboratory; - to name and characterise the most appropriate laboratory equipment, its power and peculiarities in laboratories of an outpatient medical institution; - to name and characterise most common examinations performed in laboratories of a multiprofile hospital; - to use diagnostic algorithms of different diseases; - to know conditions for accreditation of a medical laboratory according to ISO standards.
Skills
1.- to perform different types of testing using automated and manual methods; - to perform microscopy of biological material; - to evaluate clinical and laboratory aspects of reference values; - to interpret pathological results; - to conduct quality control tests.
Competences
1.To perform examinations of human biological material for diagnostics of different diseases in laboratories of a multiprofile hospital. To use modern technologies and methods, diagnostic criteria and examination algorithms for diagnostics and differential diagnostics of diseases – to interpret examination results, incl. in patient groups of different ages, and to recommend further examination activity to clinicians. To ensure the evaluation of factors influencing testing results and corrective actions in case of stated non-compliances.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Preparation of a presentation about the use of express diagnostics, its advantages and disadvantages.
In-depth research: reference values of clinical and biochemical testing results depending on the age.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
2.
Examination |
-
|
-
|
|
Assessment of knowledge – written answers to questions at the end of the study course.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Specificity of the collection of the biomaterial to be examined at different ages of the child
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Reference values for test results in different age groups of children
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Methods for screening and confirmatory laboratory diagnosis of methicillin - resistant staphylococci
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Mechanisms of resistance of laboratory-resistant gram-negative rods and laboratory diagnostic methods
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
EUCAST standard and its application in the laboratory
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Virulence factors of microorganisms, their role in pathogenesis and types of immune response against different groups of pathogens: extracellular and intracellular bacteria, viruses, fungi, bacterial capsules, bacterial exotoxins.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Specificity of diagnostics of cardiovascular diseases
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Diagnosis of diabetes
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Pathogenesis and laboratory diagnosis of alcoholic and non-alcoholic liver diseases
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Change of bile pigment substances in the norm and in pathologies
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Genetic liver disease
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Liver function in inactivation of endogenous substances and metabolism of exogenous xenobiotics, laboratory tests for its evaluation.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Laboratory diagnostics of rare and quarantine infectious agents
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Automated examination methods in microbiology
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Diagnosis of neuroborellosis
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Diagnosis of vaccine-regulated infectious diseases
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
WHO and ECDC laboratory and epidemiological surveillance for influenza and poliomyielitis
|
Total ECTS (Creditpoints):
25.95
Number of Residency Seminars:
17
Length (weeks):
22
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Richard A. McPherson, Matthew R. Pincus. Henry's Clinical Diagnosis and Management by Laboratory Methods, 23rd Edition. Sounders, 2021.
2.
Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th Edition, 2014
3.
Sarah Jane Pitt. Clinical Microbiology for Diagnostic Laboratory Scientists. 2018
4.
Barbara Detrick, Robert G. Hamilton, John L. Schmitz. Manual of Molecular and Clinical Laboratory Immunology. 8th Edition, 2016
5.
Oxford Handbook of Clinical and Laboratory Investigation. Edited by Drew Provan. Oxford University Press, 2018
6.
Preanalytical Phase Errors: Experience of a Central Laboratory Monitoring. Editor: Alexander Muacevic and John R. Adler; e7335. Published online 2020 Mar 20. 7335
Additional Reading
1.
Clinical Microbiology Procedures Handbook, Parasitology. 4th Edition, 2016
2.
Fred F. Ferri. Ferri's Best Test. A Practical Guide to Clinical Laboratory Medicine and Diagnostic Imaging. 3rd Edition, 2014
3.
Mosby's Diagnostic and Laboratory Test Reference. 13th Edition, Ed: Kathleen Deska Pagana, Timothy J. Pagana ,Theresa N. Pagana, 2016
4.
Beginner’s Guide to Real-Time PCR, Primerdisign, vers.4.3.1
Other Information Sources
1.
Practical Laboratory Medicine, Journal. Co Editors-in-Chief: William Clarke, Mike J. Hallworth
2.
The Journal of Laboratory and Clinical Medicine. The Official Publication of the Central Society for Clinical Research
3.
Clinical Chemistry and Laboratory Medicine (CCLM), Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Editor-in-Chief: Plebani, Mario
5.
http://www.ifcc.org/ifcc-communications-publications-division-(cpd)/ifcc-publications/ejifcc-(journal)/