Veidlapa Nr. M-3 (8)
Study Course Description

Cardiology (Pathology Clinical Pharmacology Methods of Examination and Interpretation of Data, Symptomatology and Pharmacotherapy)

Main Study Course Information

Course Code
ISK_234
Branch of Science
Basic medicine; Clinical Pharmacy
ECTS
4.00
Target Audience
Clinical Pharmacy
LQF
Level 7
Study Type And Form
Full-Time

Study Course Implementer

Course Supervisor
Structure Unit Manager
Structural Unit
Department of Internal Diseases
Contacts

Riga, 2 Hipokrata Street, isk@rsu.lv, +371 67042338

About Study Course

Objective

To provide students with knowledge in clinical areas – pathophysiology of cardiovascular diseases, clinical manifestations, evaluation of examinations, basic methods of treatment and pharmacotherapy options for cardiovascular diseases. The study module comprises an integrated training cycle in which the student is gradually introduced to the pathological physiology of a group of diseases, clinical pharmacology, clinical manifestations, examination possibilities, interpretation of examination data, principles of treatment and pharmacotherapy possibilities.

Preliminary Knowledge

Human anatomy, physiology and pathology, medical biochemistry, pharmacology.

Learning Outcomes

Knowledge

1.As a result of successfully completing the course, the student will have knowledge of the following: • mechanisms of origin of cardiovascular diseases; • the most common clinical manifestations and complications of cardiovascular diseases; • cardiovascular disease examination options; • basic types of treatment of cardiovascular diseases; • pharmacotherapy options for cardiovascular diseases.

Skills

1.The student will be able: • to interpret cardiovascular system examination results; • to assess pharmacotherapy for cardiovascular diseases.

Competences

1.The student will be able: • in collaboration with the medical practitioners, to determine a pharmacotherapy plan for an individual patient with a cardiovascular disease; • to assess the advantages and disadvantages of pharmacotherapy methods in relation to the patient’s examination data; • to monitor the progress of pharmacotherapy, predict side effects and plan the prevention thereof, and provide the necessary information to other medical specialists.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
The student independently studies the literature offered in the study programme, summarises the obtained information. Prepares a clinical pharmacist’s assessment in cases of pharmacotherapy for patients with cardiovascular diseases. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
Active participation in practical classes; written assignments completed in high quality and submitted on time, quality of oral answers. Test: understanding of the principles of diagnosis and treatment of cardiological diseases, including clinical case analysis, is tested.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Construction and function of the cardiovascular system. Major pathophysiological mechanisms for cardiovascular diseases.
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

The most common diseases in the cardiovascular system: morphological and functional manifestations of atherosclerosis, coronary heart disease, arterial hypertension, heart rhythm disorders and heart failure, their pathogenesis.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Key pathogenetic mechanisms as a target for the treatment of cardiovascular diseases.
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Clinical pharmacology in cardiology.
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Clinical pharmacology in cardiology.
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Clinical pharmacology in cardiology.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Complaints and anamnesis in patients with cardiovascular diseases. Cardiovascular risk factors. Physical examination of the patient. Examination methods in cardiology. Fundamentals of electrocardiography. Principles and role of echocardiography in the assessment of cardiovascular structure and function. Indications and diagnostic value of cardiac computed tomography and magnetic resonance imaging.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Complaints and anamnesis in patients with cardiovascular diseases. Cardiovascular risk factors. Physical examination of the patient. Examination methods in cardiology. Fundamentals of electrocardiography. Principles and role of echocardiography in the assessment of cardiovascular structure and function. Indications and diagnostic value of cardiac computed tomography and magnetic resonance imaging.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Complaints and anamnesis in patients with cardiovascular diseases. Cardiovascular risk factors. Physical examination of the patient. Examination methods in cardiology. Fundamentals of electrocardiography. Principles and role of echocardiography in the assessment of cardiovascular structure and function. Indications and diagnostic value of cardiac computed tomography and magnetic resonance imaging.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Arterial hypertension. Primary and secondary arterial hypertension. Risk factors, clinical manifestations, target organ damage, complications of hypertension. Non-pharmacological and pharmacological treatment of arterial hypertension.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Pharmacological agents for the treatment of cardiovascular diseases.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Atherosclerosis: epidemiology, risk factors, examinations required and principles of therapy. Coronary heart disease: epidemiology, risk factors, clinical manifestations, patient examination options. Stable angina pectoris. Acute coronary syndrome. Unstable angina. Myocardial infarction.
  1. Lecture

Modality
Location
Contact hours
On site
Specialized room
2

Topics

The concept of cardiac arrhythmias. Classification of arrhythmias, causes, pathogenesis, diagnostic principles. Principles of treatment of arrhythmias. Life-threatening arrhythmias. Acute and chronic heart failure: classification, causes, pathophysiological mechanisms, clinical manifestations, diagnosis and treatment principles.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Combination non-pharmacological and pharmacological treatment of arterial hypertension. Hypertensive crisis: ways, treatment principles and tactics. Acute coronary syndrome, its reasons. Acute coronary syndrome with and without ST elevation: clinical manifestations, complications, treatment principles and tactics. Chronic coronary artery disease: types, diagnostic methods and treatment principles.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Clinical assessment and basic principles of treatment in case of acute and chronic heart failure. Pharmacological and non-pharmacological treatment of arrhythmias.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Specialized room
2

Topics

Pulmonary artery thromboembolism. Valvular heart diseases: epidemiology, causes, investigations and treatment options. Principles for the surgical treatment of valvulas heart diseases.
Total ECTS (Creditpoints):
4.00
Contact hours:
32 Academic Hours
Final Examination:
Exam

Bibliography

Required Reading

1.

Braunwalds Heart Disease: A textbook of cardiovascular medicine, 12th ed., WB Saunders, 2022

2.

Ērglis A., Jēgere S., Kalējs O., Kalvelis A., Kamzola G., Lācis J., Mača A., Mintāle I., Narbute I., Stradiņš P., Zakke I. Hroniskas sirds mazspējas klīniskās vadlīnijas. Rīga, Latvijas Kardiologu biedrība, 2013

3.

Ērglis A., Kalvelis A., Latkovskis G., Zakke I., Jēgere S., Mača A., Narbute I., Trušinskis K., Ratobiļska S. Akūta koronāra sindroma AKS diagnostikas, loģistikas un ārstēšanas vadlīnijas. Rīga, Latvijas Kardiologu biedrība, 2011 (akceptējams izdevums)

4.

Ērglis A., Kalvelis A., Lejnieks A., Dzērve V., Latkovskis G., Mintāle I., Zakke I., Rasa I. Kardiovaskulāro slimību KVS profilakses vadlīnijas. Latvijas Kardioloģu biedrība, Rīga, 2007 (akceptējams izdevums)

5.

2013 ESH/ESC Guidelines for the management of arterial hypertension. European Heart Journal, doi:10.1093/eurheartj/eht151

6.

A. Lejnieka red. Klīniskā medicīna. Pirmā grāmata. Rīga, Medicīnas apgāds, 2010 (akceptējams izdevums)

7.

Lekciju un nodarbību materiāli.

Additional Reading

1.

2013 ESC guidelines on the management of stable coronary artery disease. European Heart Journal (2013) 34, 2949–3003 doi:10.1093/eurheartj/eht296

2.

Lüscher T., Ed. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. http://dx.doi.org/10.1093/eurheartj/eht108

3.

The Merck Manual of diagnosis and therapy, edited by Robert S.Porter, 20th ed., 2018

4.

Siegenthaler W. Differential Diagnosis in Internal medicine: From Symptom to Diagnosis. NY: Thieme Medical Publishers, 2007

Other Information Sources

1.

The Merck Manual

2.

Universal definition of myocardial infarction. Expert Consenus Document. Eur. H.J., 2007; 28: 2525-2538.

3.

Valvular Heart Disease. ESC Guidelines. Eur. H.J., 2007; 28: 230-268.

4.

Welsby P.D. Clinical history taking and examination. 2nd edition. London: Churchill Livingstone, 2002