Veidlapa Nr. M-3 (8)
Study Course Description
Clinical Pharmacology, Pharmacotherapy, Toxicology
Course Code
FFK_013
Branch of Science
Clinical medicine
ECTS
3.00
Target Audience
Clinical Pharmacy; Pharmacy
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Mārcis Zeibārts
Structure Unit Manager
Inga Urtāne
Structural Unit
Department of Pharmacology and Pharmacotherapy
Contacts
Riga, Konsula street 21, 1st floor; Marcis.Zeibarts@rsu.lv; Indra.Dumberga@rsu.lv; +371 67613517
About Study Course
Objective
To provide knowledge of specific pharmacotherapy in accordance with the pathology of the organ systems studied during the study course. To gain knowledge of the effect of therapeutic drugs on disease mechanisms and pathogenesis. The aim is to achieve that students are able to apply their knowledge of the mechanisms of action of drug substances and to integrate pharmacotherapeutic strategies in the treatment of a given case, to anticipate the course of events resulting from the treatment. Students should understand the mechanisms, indications and contraindications, adverse side effects, interactions, toxicity, and focus on the pharmacokinetic properties of each product.
Preliminary Knowledge
Anatomy, physiology, pathology, biochemistry, basics of pharmacology, clinical medicine.
Learning Outcomes
Knowledge
1.Describe and explain the principles and pharmacokinetic properties of drug groups and active substances, indications, major adverse reactions, contraindications. Characterize and explain the major interaction risks and effects of drug groups on efficacy, toxicity (if applicable).
Skills
1.On completion of the study course, students will be able to describe preparations of pharmacotherapeutic groups, formulate their mechanisms of action, indications and contraindications, as well as side effects, justify and base their opinion on the chosen treatment, modulate the applied therapy in different clinical situations. To argue reasonably on the usefulness of a pharmacotherapeutic strategy in cases of particular disease pathology; to critically analyze the usefulness of pharmacotherapeutic strategies in the context of organ system diseases.
Competences
1.On completion of the study course, students will be able to: 1. Use theoretical and practical knowledge and competence in clinical pharmacology and the use of medicinal products. 2. Choose the most appropriate medication according to the individual situation in an individualized dosage regimen to ensure optimal patient treatment and disease prevention. 3. Assess the risks and benefits of treatment. 4. Independently obtain, select and analyze information regarding medications, their use and use in the treatment process. 5. Demonstrate a scientific approach to solving topical issues, as well as have good knowledge of specific literature.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Reports, systematic reviews of specific medications, their application and use in the treatment process.
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Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Simulation of clinical situations during practical classes, modulation of therapy until a positive result is achieved, assessment – passed / failed. Participation in classes is mandatory, missed classes must be re-worked. Intermediate tests. The average grade of the intermediate tests against the grade received in the exam is 50/50.
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||
Study Course Theme Plan
FULL-TIME
Part 1
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Cardiology. CHD. Hypertension
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Cardiology. Chronic heart failure. Arrhytmias.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Pharmacological treatment of arrhythmias. Prevention of thromboembolic events. Pharmacotherapy of inflammatory heart diseases (endocarditis – infectious and rheumatic; pericarditis).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Pulmonology. Asthma. COPD. Pneumonia
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Clinical pharmacology of agents affecting gastrointestinal system. Pharmacotherapy for increased gastric secretion, peptic ulcer, Gastroesophageal reflux disease (GERD). Pharmacotherapy for gastrointestinal system.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Clinical pharmacology of agents that affect renal function. Pharmacotherapy of main syndromes of kidney damage (nephritic syndrome, nephrotic syndrome). Acute urinary tract infection (cystitis, pyelonephritis, acute urethral syndrome), treatment tactics. Chronic renal disease, pharmacotherapy.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Hypothalamic and pituitary hormone preparations. Clinical pharmacology of medication affecting thyroid gland and parathyroid. Clinical pharmacology of medicines affecting bone mineralization. Vitamin preparations. Clinical pharmacology of drugs used in the treatment of diabetes mellitus. Principles of insulin therapy.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Pharmacology of drugs affecting the adrenal cortex. Steroidal and non-steroidal anti-inflammatory drugs. Disease-modifying anti-rheumatic drugs (DMARD). Anti-gout agents. Spinal spondylosis, disc herniation with root irritation syndrome and pain syndrome, pharmacotherapy. Radiculopathies, their treatment.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Gastroenterology. GERD. Ulcer disease.
Nephrology. CKD. Urinary tract infection.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Endocrinology. Osteoporosis. Diabetes mellitus. Hypothyreosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Psychiatry/Neurology. Anxiety. Depression. Epilepsy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
3
|
Topics
|
Neurology/Rheumatology. Chronic pain. Adaptive, non-adaptive pain. Rheumatoid arthritis.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
31 Academic Hours
Final Examination:
Exam
Bibliography
Required Reading
1.
Poisoning & Drug Overdose, 8th ed., 2022
2.
Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th ed., 2022
3.
RSU E-studiju vide/RSU E-study environment
4.
Basic & Clinical Pharmacology, 15th ed., 2020
5.
Medical Pharmacology and Therapeutics, 6th ed., 2022
Additional Reading
1.
Harrison's Principles of Internal Medicine, 20th ed., 2018
2.
Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class. 6th ed., 2021
3.
Dynamed
Other Information Sources
4.
ClinicalKey