Veidlapa Nr. M-3 (8)
Study Course Description
Clinical Immunology and Immunopharmacology
Course Code
BUMK_076
Branch of Science
Clinical medicine; Immunology
ECTS
2.00
Target Audience
Clinical Pharmacy; Medical Services
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Inese Mihailova
Structure Unit Manager
Juta Kroiča
Structural Unit
Department of Biology and Microbiology
Contacts
Riga, 16 Dzirciema Street, bmk@rsu.lv, +371 67061584
About Study Course
Objective
To promote acquisition of knowledge of the main types of immunopathology and related diseases: immunodeficiencies, autoimmunity, allergies, infections of the immune system, etc.; the most important parameters characterising human immunity, options for the determination thereof, indications, clinical interpretation and use in the diagnosis and differential diagnosis of various diseases; immunoprophylaxis and immunocorrection techniques, agents, indications of use and side effects; clinical immunopharmacology agents.
Preliminary Knowledge
Normal anatomy, histology and physiology – must know the structure of the normal immune system, as well as the basic principles of medical genetics, microbiology, biochemistry, pathological physiology and the functions of the immune system.
Learning Outcomes
Knowledge
1.As a result of completing the study course, students obtain knowledge that allows to: • understand and describe the functioning of the immune system in normal conditions and in case of various immune pathologies; • name and describe the most important immunological test methods that characterise different components of immunity: humoral immunity, cellular immunity, complement system, phagocytosis; • know the aetiology, clinic, immunopathological diagnosis and therapy of immunopathological conditions.
Skills
1.The student will be able to: • orient in the principles of immunotherapy, groups of immunomodulators; • orient in the most important immunomodulatory preparations, their side effects and prevention of the side effects.
Competences
1.As a result of completing the study course, students will be able to: • monitor the progress of pharmacotherapy in case of immunopathologies, evaluate the results and prepare the necessary information for other medical specialists.
Assessment
Individual work
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Individual work |
-
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-
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To find immunopharmaceuticals from different immunopreparation groups and analyse their mechanisms of immunological action, indications, side effects and methods of administration in a seminar.
To prepare an oral presentation on an immunopharmacological preparation.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
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Examination
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Examination |
-
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-
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• discussion (Q&A) on theoretical and practical issues in clinical immunopharmacology;
• test work;
• oral report on an immunopharmacological agent.
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Study Course Theme Plan
FULL-TIME
Part 1
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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2
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Topics
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Normal immune defence mechanisms. Specific immunity. Humoral and cellular immunity. Antimicrobial immunity.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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2
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Topics
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Types of immunopathologies. Clinical manifestations and laboratory diagnosis of immunodeficiency.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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2
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Topics
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Causes of immunodeficiencies. Primary and secondary immunodeficiencies. Clinical and laboratory diagnostic methods. Immunocompromised patient. Immunoglobulin therapy in case of various immunodeficiencies.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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2
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Topics
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Allergy as a type of immunopathology. Types of allergies. Immunological diagnosis. Specific hyposensitisation.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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2
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Topics
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Autoimmunity and autoimmune diseases. Clinical and immunological diagnosis of autoimmune diseases. Autoantibodies.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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3
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Topics
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Types of immunomodulatory therapies. Immunostimulating and immunosuppressive therapy. Plasmapheresis.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Specialized room
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3
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Topics
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Immunosuppressive therapy. Prednisolone pharmacotherapy, anti-inflammatory and immunosuppressive effects thereof. Cytostatics. Indications for use. Immunological side effects of immunosuppressive therapy. Biological immunomodulatory medicines.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Specialized room
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3
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Topics
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Antiviral immunity-enhancing medicines. Adaptogens, herbal preparations, minerals and vitamins as immunomodulators. Evaluating the effectiveness of immunotherapy: clinical and immunological criteria. Immunotherapy problems.
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Total ECTS (Creditpoints):
2.00
Contact hours:
22 Academic Hours
Final Examination:
Exam
Bibliography
Required Reading
1.
I.Mihailova. J.Kroiča Klīniskā imunoloģija. Grāmatā Klīniskā medicīna 3. daļa A.Lejnieka redakcijā . Rīga 2012. (akceptējams izdevums)
2.
Helen Chapel. Essentials of Clinical Immunology. /6th edition/ – Blackwell. 2022
3.
Ch.A.Janeway, Jr., P.Travers. Immunobiology. The Immune System in Health and Disease. 2nd Edition/, Published by Current Biology Ltd. London, San Francisco and Philadelphia, 2022
Other Information Sources
1.
Mod. Asp. Immunobiology (www.immunotools.com)
2.
www.immunelab.boom.ru/immunitet.html
3.
www.labinfo.ru/bibl/knigi/nimm/00.htm
4.
www.immunologia.narod.ru/1.htm
5.
www.med-stud.narod.ru/natur/paediatrics/immdef.html