Veidlapa Nr. M-3 (8)
Study Course Description
Pathology
Course Code
PAK_044
Branch of Science
Clinical medicine; Pathology
ECTS
15.00
Target Audience
Medicine
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Ilze Štrumfa
Structure Unit Manager
Ilze Štrumfa
Structural Unit
Department of Pathology
Contacts
9A Kuldigas Street, Riga, LV-1007, Latvija; pak@rsu.lv; phone +371 67815096
About Study Course
Objective
1. To ensure the studies in human pathology, covering morphological and functional aspects of general pathological processes and pathogenesis of different diseases. Thus, the course serves as a theoretical basis for further acquisition of clinical courses, developing comprehensively educated doctors. The programme in pathology should provide an integrated understanding of the morphological and functional components of disease pathogenesis.
2. To provide a practical overview of pathology as a diagnostic branch of medicine at a level appropriate to the needs of a general practitioner.
Preliminary Knowledge
Cell biology, anatomy, histology, genetics, normal physiology and biochemistry. For the acquisition of integrated knowledge, it is recommended to study the course concomitantly with the introduction to clinical courses, such as diagnosis in internal medicine and general surgery.
Learning Outcomes
Knowledge
1.Upon successful completion of the study course, the student will be able to explain the nature, causes and risk factors of various diseases and general pathological processes, pathogenesis and its reflection in clinical processes, laboratory and imaging diagnosis, potential complications, consequences and outcomes. General pathological processes to be learned include general aspects of inflammation and wound healing, fever, peripheral circulatory disorders, hypoxia, tumour development, cell damage and compensatory adaptation, fluid, electrolyte and acid-based imbalance and stress response. Special pathology part includes acquisition of pathogenesis of the cardiovascular, lung, kidney, gastrointestinal, liver and bile duct, pancreas, bone, central nervous system, gynecological and reproductive, breast, hematological and endocrine diseases as basis for further clinical studies.
Skills
1.The student will be able to reasonably assess the pathogenesis of common diseases, to relate them to clinical manifestations and diagnostic bases of the diseases, and to take practical steps to organise tissue and / or laboratory examinations required by GP or a specialist, interpret and critically analyze their results.
Competences
1.The competences in pathogenesis of different diseases will allow to interpret clinical situations in regard to the underlying morphological and functional events, to predict the outcomes and complications. The theoretical understanding of the disease will become the basis for developing evidence-based clinical competence.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
During the studies the student must acquire the study materials of the Department of Pathology corresponding to the thematic plan.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Knowledge is assessed by regular multiple-choice tests and colloquia during the studies, as well as by the examination at the end of the course. The skills are assessed by clinical exercises (including 2 image analysis) in regular classes, colloquia (consisting of 100 theoretical questions and interpretation of laboratory examinations) and a written examination at the end of the study course, consisting of 150 theoretical questions and 4 image analysis, clinical tasks or interpretation tasks of laboratory examinations). The argumentation in the colloquia and exam show students’ competence in applying the obtained knowledge in order to explain and analyse clinical situations, to predict the outcome and/or complications.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Introduction into pathology. The concept of disease process, aetiology and pathogenesis
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammation: the basics and morphological manifestations.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Basic characteristics of tumours.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Atherosclerosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Disease as a process. Definitions and terminology.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cell damage.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Compensatory adaptation processes.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Peripheral circulatory disorders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Hypoxia.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Nature and manifestations of acute inflammation.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Nature and manifestations of chronic inflammation.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Systemic and laboratory manifestations of inflammation. Mediators of inflammation.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Fever. Disturbances of thermoregulation.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Basic characteristics of tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
The spread of malignant tumours around the body. Insights into the TNM classification.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Breast pathology.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Tumours of the soft tissue. Melanocytic tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Tumours of the soft tissue. Melanocytic tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Renal and urogenital tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Renal and urogenital tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Hypohydration. Hyperhydration.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Disturbances of acid-base balance.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diffuse renal diseases.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Turbointerstitial, cystic and vascular kidney diseases. Urolithiasis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Acute kidney failure. Disturbances of electrolyte balance.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Chronic renal disease. Causes of chronic renal disease.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cardiovascular diseases: atherosclerosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cardiovascular diseases: inflammation. Insights into cardiomyopathy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cardiovascular diseases: heart valve diseases, their causes and haemodynamic effects.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Acute and chronic heart failure.
|
Total ECTS (Creditpoints):
7.50
Contact hours:
80 Academic Hours
Final Examination:
Test (Semester)
Part 2
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Oesophageal and gastric pathology.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Pathology of large intestine.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liver pathology.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Jaundice/ hyperbilirubinaemia: pathological mechanisms and types.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammation and dysfunction of the oesophagus, stomach and duodenum.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Gastric and oesophageal tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammatory diseases and functional disorders of the large intestine. Diarrhoea, vomiting and the association of these conditions with dehydration. Malabsorption.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammatory diseases and functional disorders of the large intestine. Diarrhoea, vomiting and the association of these conditions with dehydration. Malabsorption.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Benign and malignant tumours of the large intestine.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diffuse liver diseases.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Focal liver lesions. Tumours: clinically relevant manifestations of pathogenesis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diseases of gall bladder and bile ducts.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diseases of pancreas.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cirrhosis of the liver. Liver failure. Jaundice and its differential diagnosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cirrhosis of the liver. Liver failure. Jaundice and its differential diagnosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Non-oncological lung diseases. The role of inflammation in the pathogenesis of clinically relevant conditions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Non-oncological lung diseases. The role of inflammation in the pathogenesis of clinically relevant conditions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Tuberculosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Lung tumours. Pleural pathology.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Lung tumours. Pleural pathology.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Respiratory pathological physiology.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Pathology of red blood cells.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Pathology of red blood cells.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Non-neoplastic pathology of white blood cells.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Platelet disorders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Coagulation disorders. Thrombosis, thromboembolism, pulmonary embolism (PE).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Haematological tumours and their differential diagnosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Reproductive pathology I.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Reproductive pathology II: Impaired fertility. Pathology of pregnancy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Endocrine pathology I: thyroid and parathyroid gland diseases.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Endocrine pathology II: diseases of the pituitary and adrenal glands.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diabetes mellitus; its early and late complications.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diabetes mellitus; its early and late complications.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Focal pathological processes in bones: fractures and their healing, inflammation and tumours.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Bone pathology: diffuse bone diseases.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Disturbances of calcium turnover.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Autoimmune diseases: pathogenesis of selected clinical entities.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Vascular pathology of the central nervous system (CNS). The role of atherosclerosis in the pathogenesis of clinically relevant diseases.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammatory and degenerative diseases of the CNS. Tumours of the CNS.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Colloquium.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Acute kidney failure and chronic kidney disease: pathogenetic link between processes in kidneys and other organs. Diagnosis master class as part of a pathology course.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Acute kidney failure and chronic kidney disease: pathogenetic link between processes in kidneys and other organs. Diagnosis master class as part of a pathology course.
|
Total ECTS (Creditpoints):
7.50
Contact hours:
80 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
RSU MF Patoloģijas katedras lekciju un nodarbību e-materiāli patoloģijā // Original study materials, prepared by the teachers' team of the Department of Pathology, RSU. The materials are available in the e-studies
Additional Reading
1.
Robbins and Cotran. Pathologic Basis of Disease. 8th ed. Kumar, V., Abbas, A. K., Fausto, N., Aster, J. (eds). Elsevier, 2021.
2.
Robbins. Basic Pathology. 7th ed. Kumar, V., Cotran, R. S., Robbins, S. L. (eds). Saunders, Philadelphia, 2018, 873 lpp.
3.
Pathophysiology: the Biologic basis for Disease in Adults and Children. 5th ed. Ar CD-ROM. McCance, K. L., Huether, S. E. (eds). Elsevier Mosby, USA, 1780 lpp. 2019
4.
Rosai and Ackerman's. Surgical Pathology. 2 sējumu komplekts ar CD-ROM, 3000 lpp., Mosby, 2018.
5.
Sternberg's Diagnostic Surgical Pathology. 5th ed. Mills, S. E, Carter, D., Greenson, J. K, Reuter, V. E., Stoler, M. H. (eds). 3104 lpp, Lippincott Williams and Wilkins, 2015.