Veidlapa Nr. M-3 (8)
Study Course Description

Endocrinology

Main Study Course Information

Course Code
RSS_017
Branch of Science
Clinical medicine
ECTS
9.00
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To ensure the acquisition and improvement of theoretical knowledge and practical skills in enocrinology, in accordance with the requirements of the specialty of sexologist, sexopathologist, in order to prepare the doctor for certification in the specialty of sexologist, sexopathologist, in accordance with the regulatory documents of the Republic of Lithuania.

Learning Outcomes

Knowledge

1.Able to present and explain questions about a child's normal sexual maturation, sexual maturation disorders, premature puberty, delayed puberty, prolonged puberty, benign variants of early sexual maturation, sexual differentiation and sexual development disorders, inter-sexuality, same hermaphroditism, pseudo-hermaphroditism, gonadal dysgenesis. Knows the anatomy and functions of the hypothalamus-pituitary system; sex hormones, their physiological effects in the male body (gonadotropin-releasing hormone, follicle-stimulating hormone, luteinizing hormone, prolactin, testosterone); in the female body (gonadotropin-releasing hormone, follicle-stimulating hormone, luteinizing hormone, prolactin, testosterone, estrogens, progestogens). Knows the etiology, pathogenesis, clinic, diagnosis and treatment methods of the following diseases: hypogonadotropic hypogonadism, hypergonadotropic hypogonadism, diabetes, adiposity, thyroid diseases (hypothyroidism, hyperthyroidism). Understands the pathogenesis and treatment options of sexual disorders caused by the aforementioned diseases. Knows the basic principles of hormonal therapy for transsexual persons.

Skills

1.Performs anamnesis collection, clinical and instrumental diagnosis of endocrinological diseases; means treatment for endocrinological patients; interprets the results of clinical analyzes of patients with endocrine pathology (glucose regulation, lipid profile, thyroid hormones, sex hormones, adrenal hormones); interprets the results of instrumental and radiological examinations of patients with endocrine pathology (ultrasonography, computed tomography, magnetic resonance); diagnoses and treats endocrinological diseases under the supervision of a certified endocrinologist; diagnosis and treatment of sexual disorders (erectile dysfunction, premature ejaculation, libido disorders, orgasm disorders) caused by endocrinological diseases under the supervision of a certified endocrinologist; fills out the medical documentation.

Competences

1.Draws up diagnostic algorithms, analyzes and differentiates endocrinological diseases; understands, evaluates and chooses various treatment methods for endocrinological diseases and sexual disorders caused by endocrinological diseases; evaluates and draws up a treatment plan for endocrinological patients within the limits of competence; analyzes the course of treatment and corrects it as necessary under the guidance of a certified endocrinologist; analyzes treatments and draws conclusions based on the principles of evidence-based medicine.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
1. Independently studies the literature related to the course topics; 2. Independently prepares for seminars; 3. Independently collects data on the anamnesis of the disease, objectively examines the patient, formulates the primary diagnosis, which is discussed with the instructor; 4. Familiarizes with and analyzes medical documentation; 5. Completes medical documentation; 6. Independently executes the instructions of the certified specialist.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
Practical works 90%. (Performs clinical diagnosis and treatment of endocrinological diseases). Final test: oral test, during which the resident presents a diary with a list of performed manipulations and operations - 10%. Attendance at seminars is mandatory. Absence of 20% of seminars is allowed for a valid reason. Late practical work must be completed.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
-
-

Topics

Normal sexual maturation of the child. Puberty disorders. Premature puberty. Delayed puberty. Prolonged puberty. Benign variants of precocious puberty. Disorders of sexual differentiation and sexual development. Inter-sexuality. True hermaphroditism. Pseudo-hermaphroditism. Gonadal dysgenesis. Complete gonadal dysgenesis.
  1. Seminar

Modality
Location
-
-

Topics

Hypothalamus - pituitary system, anatomy and functions. Sex hormones, their physiological effects in the male body (gonadotropin-releasing hormone, follicle-stimulating hormone, luteinizing hormone, prolactin, testosterone). Sex hormones and their physiological effects in the female body (gonadotropin-releasing hormone, follicle-stimulating hormone, luteinizing hormone, prolactin, testosterone, estrogens, progestogens).
  1. Seminar

Modality
Location
-
-

Topics

Hypogonadotropic hypogonadism, etiology, pathogenesis. Clinic, diagnostics. Image diagnostic methods, laboratory diagnostic methods. Hypergonadotropic hypogonadism, etiology, pathogenesis. Clinic, diagnostics. Image diagnostic methods, laboratory diagnostic methods. Sexual disorders caused by hypogonadism. Treatment of hypogonadism.
  1. Seminar

Modality
Location
-
-

Topics

Diabetes: type 2 diabetes, type 1 diabetes. Etiology, pathogenesis. Microvascular complications of diabetes, their impact on sexual function. Diabetic neuropathy, its effect on sexual function. Treatment options for microvascular complications and diabetic neuropathy. Adiposity, etiology, pathogenesis. The role of adiposity in the development of hypogonadism. Treatment of adiposity.
  1. Seminar

Modality
Location
-
-

Topics

Thyroid diseases: hypothyroidism, hyperthyroidism. Effects of thyroid hormone disorders on sexual function.
  1. Seminar

Modality
Location
-
-

Topics

Basic principles of hormonal therapy for transsexual persons.
Total ECTS (Creditpoints):
9.00
Number of Residency Seminars:
6
Length (weeks):
7
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Brinkmann, A., O.1994. Androgen Action in Health and Desease. Topical Endocrinolog. Suppl. 7, 25-56.

2.

Erenpreiss, J., Fodina, V., Pozarska, R., Zubkova, K., Dudorova, A. and Pozarskis, A. 2019. Prevalence of testosterone deficiency among aging men with and without morbidities. Aging Male. 6(1), 1-5.

3.

Feldman, I. R. et al. 2002. Age trends in the level of serum testosterone and other hormones in middle aged men: longitudinal results from the Massachusetts Male aging study. J Clin Endocrinol Metab. 87-92.

4.

Jockenhovel, F. 2004. Male Hypogonadism. Bremen: Germany International Medical Publishers.

5.

Kula, K. and Slowikowska-Hilczer, J. 2000. Sexual differentiation of the human brain. Przegl Lek. 57(1), 41-44.

6.

Lunenfeld, B., Mskhalaya, G., Zitzmann, M. et al. 2015. Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men. The Aging Male. 2, 1-11.

7.

McBride, J. A., Culley, C. C. and Coward, R. M. 2015. Diagnosis and management of testosterone deficiency. Asian Journal of Andrology. 17, 177-186.

8.

Požarskis, A. and Ērenpreiss, J. 2010. Late – onset hypogonadism: review of the problem. Procceedings of the Latvian Academy of Sciences. Section B, 64(3/4), 93-97.

9.

Požarskis, A. and Lejnieks, A. 2019. Detection of Late - onset hypogonadism in Men with chronic internal diseases. Proceedings of the Latvian Academy of Sciences. Section B. 73(1 (718)), 24-33.

10.

Lejnieks, A., et al. 2010. Klīniskā medicīna. Rīga: Medicīnas apgāds.

Additional Reading

1.

Tajar, A., Huhtaniemi, I. T., O'Neill, T. W. et al. 2012. Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS). J Clin Endocrinol Metab, 97(5), 1508-1516.

2.

Vigen, R., O'Donnell, C. I., Baron, A. E. et. al. 2013. Association of testosterone therapy with mortality, myocardial infarction and stroke in men with low testosterone levels. JAMA. 310(17), 1829-1836.

Other Information Sources

1.

WPTAH. 2012. Standards of Carefor the Health of Transsexual, Transgender, and Gender –Nonconforming People, The World Professional Association for Transgender Health. Available at: https://www.wpath.org/publications/soc