Veidlapa Nr. M-3 (8)
Study Course Description
Pharmacy Dosage Form Technology
Course Code
ZFTK_001
Branch of Science
-
ECTS
12.00
Target Audience
Pharmacy
LQF
Level 7
Study Type And Form
Full-Time; Part-Time
Study Course Implementer
Course Supervisor
Venta Šidlovska
Structure Unit Manager
Baiba Mauriņa
Structural Unit
Department of Applied Pharmacy
Contacts
Riga, 16 Dzirciema Street, zftk@rsu.lv, +371 67061547
About Study Course
Objective
The aim of the study course is to provide an opportunity to acquire the theoretical justification of preparation of extemporal drug dosage forms and acquire practical proficiency and skills which are necessary for the preparation of different dosage forms in pharmacy.
Preliminary Knowledge
Organic Chemistry, Inorganic Chemistry, Physical Pharmacy, Mathematics, Plant and Animal Biology, Pharmacognosy, Microbiology, Pharmaceutical Chemistry.
Learning Outcomes
Knowledge
1.On successful completion of the course, the student will know the theoretical justification of preparation of extemporaneous dosage forms and general conceptions of pharmaceutical incompatibility; in the result of acquisition of the course, student will be able to answer questions about pharmaceutical compounding and clarify and justify the order of addition of all components for each dosage form.
Skills
1.Student will be able to prepare dosage forms quickly enough and with good quality in the result of acquisition of the course. The student will be able to apply methods of pharmaceutical technology for preparation of extemporaneous dosage forms. The student will be able to predict possible incompatibilities in different prescriptions.
Competences
1.On completion of the ocurse the student will be able to prepare different extemporaneous dosage forms in pharmacy.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Individual work by writing protocols and solving case studies.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
5 written colloquiums for full time students, 3 written colloquiums for part-time students, examination consisting of two theoretical questions and one prescription.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Powders as dosage form. The characteristics and preparation of powders.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Powders as dosage form. The characteristics and preparation of powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of single and mixed powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of single and mixed powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of single and mixed powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of single and mixed powders.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liquid dosage forms. The characteristics and preparation of liquid dosage forms.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liquid dosage forms. The characteristics and preparation of liquid dosage forms.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liquid dosage forms. The characteristics and preparation of liquid dosage forms.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of aqueous and non-aqueous liquids.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of aqueous and non-aqueous liquids.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of aqueous and non-aqueous liquids.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liquid preparations for oral use (mixtures) as dosage form. The characteristics and preparation of mixtures.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Liquid preparations for oral use (mixtures) as dosage form. The characteristics and preparation of mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different mixtures.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Drops as dosage form. Characteristics and preparation of drops for oral and external use.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of drops for oral and external use.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different prescriptions. Practical test. Case studies. Class test.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Preparation of different prescriptions. Practical test. Case studies. Class test.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Suspensions as dosage form. Characteristics and preparation of suspensions.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Suspensions as dosage form. Characteristics and preparation of suspensions.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Suspensions as dosage form. Characteristics and preparation of suspensions.
|
Total ECTS (Creditpoints):
6.00
Contact hours:
64 Academic Hours
Final Examination:
Test (Semester)
Part 2
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Suspensions for oral use with industrially prepared bases.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Emulsions as dosage form. Characteristics and preparation of suspensions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suspensions for oral and external use.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suspensions for oral and external use.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suspensions for oral and external use.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Rectal and vaginal preparations. Characteristics and preparation.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Rectal and vaginal preparations. Characteristics and preparation.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suppositories and pessaries.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Sterile and aseptic liquid dosage forms. Characteristics and preparations.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of sterile and aseptic preparations.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Compatibility and incompatibility.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different prescriptions.
Practical test.
Case studies.
Class test.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different prescriptions.
Practical test.
Case studies.
Class test.
|
Total ECTS (Creditpoints):
6.00
Contact hours:
64 Academic Hours
Final Examination:
Exam (Written)
PART-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Powders as dosage form. The characteristics and preparation of powders.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Powders as dosage form. The characteristics and preparation of powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of single and mixed powders.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of single and mixed powders.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Liquid dosage forms. The characteristics and preparation of liquid dosage forms.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Liquid dosage forms. The characteristics and preparation of liquid dosage forms.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of aqueous and non-aqueous liquids.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of aqueous and non-aqueous liquids.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Liquid preparations for oral use (mixtures) as dosage form. The characteristics and preparation of mixtures.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Liquid preparations for oral use (mixtures) as dosage form. The characteristics and preparation of mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different mixtures.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different prescriptions. Practical test. Case studies. Class test.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Suspensions as dosage form. Characteristics and preparation of suspensions.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Suspensions as dosage form. Characteristics and preparation of suspensions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suspensions for oral and external use.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of suspensions for oral and external use.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Semi-solid preparations for cutaneous application. Characteristics and preparation of ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointments.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Compatibility and incompatibility.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different prescriptions.
Practical test.
Case studies.
Class test.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different prescriptions.
Practical test.
Case studies.
Class test.
|
Total ECTS (Creditpoints):
9.00
Contact hours:
96 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Pharmaceutical compounding and dispensing / John F. Marriott ... [et al.]. London ; Chicago : Pharmaceutical Press, 2010. xv, 288 lpp., 2nd ed.
2.
Sandell Erik. Pharmazeutics. Schwedish Pharmazeutical Press. - Stockholm, 1983.- 242 p.
3.
Metodiskie norādījumi. 16 tabulas. Sastādītāji: Dr.pharm. V.Šidlovska, Dr. pharm. A.Felsbergs .- LMA, 1998.
Additional Reading
1.
Handbook of extemporaneous preparation : a guide to pharmaceutical compounding / edited by Mark Jackson, Andrew Lowey, on behalf of the NHS Pharmaceutical Quality Assurance Committee. London ; Chicago : Pharmaceutical Press. 2010, xvi, 464 lpp.
2.
Voigt Rudolf. Pharmazeutische Technologie // Für Studium und Beruf. – Achte durchgesehene Auslage.- Berlin/Wiesbaden, 1995. – 800 S.
3.
Технология лекарственных форм: Учебник (в 2 томах). Том 1. Т.С.Кондратьева, Л.А.Иванова, Ю.И.Зеликсон и др.; Под ред. Т.С.Кондратьевой. – Москва: Медицина, 1991. – 496 с.
4.
Bauer. Frömming. Führer. Lehrbuch der Pharmazeutischen Technologie mit einer Einführung in die Biopharmazie. 8. Auflage. Widdenschaftliche Verlagsgesellschaft mbH Stuttgart, 2006.- XVI; 487 S.
5.
Машковский М.Д. Лекарственние средства (в 2 томах). – 15-е издание. – Москва: Новая волна, издатель Умеренков, 2007. – 1206 с.