Veidlapa Nr. M-3 (8)

Study Course Description

Clinical Chemistry and Coagulogy

Main Study Course Information

Course Code

RLA_004

Branch of Science

Clinical medicine; Medicinal Biochemistry

ECTS

13.05

Target Audience

Medicine

LQF

Level 8

Study Course Implementer

Course Supervisor

Jeļena Storoženko

Residency Speciality

Speciality

Laboratory doctor

Supervisor of Medical Speciality

Jeļena Storoženko

Contacts

About Study Course

Objective

To prepare laboratory doctors capable of conducting clinical chemistry and coagulogic examinations using clinical chemistry laboratory equipment and procedures. To obtain knowledge about clinical chemistry and coagulogic examination methods, interpretation of indicators, critical values and their meaning in the selection of further examination tactics. To master internal and external quality control principles in clinical chemistry and coagulogy – calibration curves, control cards, their evaluation criteria.

Learning Outcomes

Knowledge

1.- to describe principles of operation of clinical chemistry equipment; - to evaluate changes in biochemical and coagulogical indicators; - to characterise hydrocarbon metabolism, norm and pathology; - to characterise nitrogen metabolism, norm and pathology; - to characterise lipid metabolism, norm and pathology; - to create and evaluate calibration curves, control cards.

Skills

1.- to conduct clinical routine biochemical tests using biochemical analysers; - to determine coagulation indicators; - to conduct quality control tests for biochecmical and coagulogical analysers; - to determine protein fractures using electrophoresis method; - to evaluate biochemical and coagulation profile indicators.

Competences

1.Examination of a biological material to determine physiological properties and pathological processes in a human body in order to perform differential diagnostics of different diseases and to ensure the quality of examinations.

Assessment

Individual work

Title	% from total grade	Grade
1. Individual work	-	-
Preparation of a presentation about platelet circulatory system and plasma coagulation haemostasis. In-depth research: acute phase proteins, their significance in diagnostics of inflammatory diseases; clinical application of the protein fracture analysis.

Examination

Title	% from total grade	Grade
1. Examination	-	-
2. Examination	-	-
Assessment of knowledge – written answers to questions at the end of the study course.

Study Course Theme Plan

FULL-TIME

Part 1

Seminar

Modality	Location
On site	Auditorium

Topics

Vascular platelet system

Seminar

Modality	Location
On site	Auditorium

Topics

Plasma coagulation haemostasis

Seminar

Modality	Location
On site	Auditorium

Topics

Basics of clinical chemistry. Medical enzymology

Seminar

Modality	Location
On site	Auditorium

Topics

Carbohydrate metabolism in the norm and in pathologies

Seminar

Modality	Location
On site	Auditorium

Topics

Nitrogen metabolism in the norm and in pathologies

Seminar

Modality	Location
On site	Auditorium

Topics

Lipid metabolism in the norm and in pathologies

Seminar

Modality	Location
On site	Auditorium

Topics

Acute phase proteins, their role in the diagnosis of inflammatory diseases

Seminar

Modality	Location
On site	Auditorium

Topics

Methods for the determination of hormones

Seminar

Modality	Location
On site	Auditorium

Topics

Examination of thyroid and sex hormones and interpretation of results

Seminar

Modality	Location
On site	Auditorium

Topics

Clinical application of protein fraction analysis. Proteinuria

Seminar

Modality	Location
On site	Auditorium

Topics

Use of iron metabolism in the differential diagnosis of anemia

Total ECTS (Creditpoints):

13.05

Number of Residency Seminars:

Length (weeks):

Final Examination:

Residency exam (Theory and practice)

Bibliography

Required Reading

Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd Edition, 2017

Preanalytical Phase Errors: Experience of a Central Laboratory Monitoring Editor: Alexander Muacevic and John R Adler; e7335. Published online 2020 Mar 20. doi: 10.7759/cureus.7335

Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th Edition, 2014

Mosby's Diagnostic and Laboratory Test Reference. 13th Edition, Kathleen Deska Pagana, Timothy J. Pagana, Theresa N. Pagana, 2016

Oxford Handbook of Clinical and Laboratory Investigation. Edited by Drew Provan. Oxford University Press, 2018

Additional Reading

Clinical Microbiology for Diagnostic Laboratory Scientists. Sarah Jane Pitt, 2018

LPractical Laboratory Medicine, Journal. Co Editors-in-Chief: William Clarke, Mike J. Hallworth

Volume 35-2. Diagnostic Testing for Enteric Pathogens. An Issue of Clinics in Laboratory Medicine.1st Editor. Alexander McAdam, 2015

The Journal of Laboratory and Clinical Medicine, The Official Publication of the Central Society for Clinical Research

Clinical Chemistry and Laboratory Medicine (CCLM), Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM), Editor-in-Chief: Plebani, Mario.

Other Information Sources

Practical Laboratory Medicine. Journal. Co Editors-in-Chief: William Clarke, Mike J. Hallworth

The Journal of Laboratory and Clinical Medicine. The Official Publication of the Central Society for Clinical Research

Clinical Chemistry and Laboratory Medicine (CCLM), Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM), Editor-in-Chief: Plebani, Mario.

http://www.ifcc.org/ifcc-education-division/webinars/

http://www.ifcc.org/ifcc-communications-publications-division-(cpd)/ifcc-publications/ejifcc-(journal)/