Veidlapa Nr. M-3 (8)
Study Course Description

Clinical and Laboratory Immunology

Main Study Course Information

Course Code
RLA_009
Branch of Science
Clinical medicine; Immunology
ECTS
7.95
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To prepare laboratory doctors capable of using immunological examination methods using necessary equipment, procedures and observing examination rules. To obtain theoretical and practical knowledge on most important parameters characterising human immunity, to interpret the obtained results and to be able to choose further examination tactics. To be able to act, if critical values are obtained. To master internal and external quality control principles of immunological examination methods.

Learning Outcomes

Knowledge

1.- to characterise the structure and main functions of the immune system; - to describe possibilities of using different methods in diagnostics of immune system diseases; - to evaluate the most essential parameters characterising human immunity; - to describe mechanisms of immune system disorders.

Skills

1.- to perform laboratory examinations for diagnostics of immune system diseases: ELISA, IFA. - to perform HLA typing using molecular biological methods; - to perform autoantibody tests; - to interpret immunological tests and their prognostic significance.

Competences

1.To perform laboratory diagnostics of immune system diseases. To use modern technologies and methods, diagnostic criteria and examination algorithms for diagnostics and differential diagnostics of diseases. To interpret results and to recommend further examination activity to clinicians.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Preparation of a presentation. In-depth research: Principles of HLA typing methods.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
2.

Examination

-
-
Assessment of knowledge – written answers to questions at the end of the study course.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Structure and functions of the immune system
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Pathology of the immune system and its mechanism
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Clinical immunogenetics and transplant immunology
Total ECTS (Creditpoints):
7.95
Number of Residency Seminars:
3
Length (weeks):
6
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Manual of Molecular and Clinical Laboratory Immunology. 8th Edition, Ed: Barbara Detrick, Robert G. Hamilton, John L. Schmitz. 2016

2.

Immunology & Serology in Laboratory Medicine. 5th Edition, 2013

3.

Autoantibodies. Edited by Yehuda Shoenfeld, M. E. Gershwin, Pier-Luigi Meroni. Elsevier Science, 3rd Revised edition, 2013

4.

Henry's Clinical Diagnosis and Management. by Laboratory Methods. 23rd Edition, Ed: Richard A. McPherson, Matthew R. Pincus. Sounders, 2016

Additional Reading

1.

Fred F. Ferri. Ferri's Best Test. A Practical Guide to Clinical Laboratory Medicine and Diagnostic Imaging. 3rd Edition, 2014

2.

Oxford Handbook of Clinical and Laboratory Investigation. Edited by Drew Provan. Oxford University Press, 2018

3.

Kathleen Deska Pagana, Timothy J. Pagana, Theresa N. Pagana. Mosby's Diagnostic and Laboratory Test Reference. 13th Edition, 2016

4.

Clinical Immunology Journal. Editor-in-Chief George C. Tsokos.

Other Information Sources

1.

Practical Laboratory Medicine, Journal. Co Editors-in-Chief: William Clarke, Mike J. Hallworth

2.

Clinical Chemistry and Laboratory Medicine (CCLM). Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Editor-in-Chief: Plebani, Mario

5.

The Journal of Immunology