Veidlapa Nr. M-3 (8)
Study Course Description
Anatomical, Physiological and Biochemical Aspects of Laboratory Diagnostics
Course Code
SL_136
Branch of Science
Clinical medicine
ECTS
3.00
Target Audience
Life Science
LQF
Level 7
Study Type And Form
Full-Time; Part-Time
Study Course Implementer
Course Supervisor
Maksims Mukāns
Structure Unit Manager
Andrejs Ivanovs
Structural Unit
Statistics Unit
Contacts
Balozu Street 14, Riga, LV-1048
About Study Course
Objective
To facilitate the acquisition of theoretical knowledge about chemical and physiological processes in the human body in relation to its functions. To improve the understanding of modern laboratory diagnostic possibilities and their interpretation.
Preliminary Knowledge
Knowledge in chemistry and human anatomy according to the programm requirements.
Learning Outcomes
Knowledge
1.Students will acquire knowledge and understanding of biochemical and physiological processes taking place in different human organ systems and the various tests characterising this process to be applied in laboratory diagnostics. Will know the intervals and clinical relevance of the different laboratory indicators in the rapporteurs. Will learn the medical terminology that characterizes processes in the human body.
Skills
1.Will be able to assess the relevance of the data obtained for the necessary analysis, will be able to independently develop a laboratory examination data analysis plan in biomedical studies, draw conclusions based on the resulting calculations. Will be able to interpret the examinations in laboratories and integrate them into the design of the studies, understanding the nature of the examinations. In line with changes in investigations, it will be possible to explain the significance, possible causes and potential consequences of these changes.
Competences
1.Will be able to cooperate with professionals in the medical field, understanding the terminology used and the situations described in the research tasks, propose ideas on the relationship of the research processes, recommend further and in-depth research directions.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
10 points
|
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Short tests in classes |
50.00% from total grade
|
10 points
|
|
A quick multiple choice test in each practical class. |
||
|
2.
Final test |
50.00% from total grade
|
10 points
|
|
Face-to-face multiple choice test on paper for one hour. |
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Introduction to anatomy, physiology and laboratory diagnostics. Human organ systems and basic functions thereof. Test types, test sensitivity, specificity. Test interpretation – Referential intervals, deviations from normal.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Blood and components thereof. Full blood picture: red blood cells, white blood cells, platelets, haemoglobin, haematocrit, EGR.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Digestive system. Blood biochemical indicators: proteins, liver tests and other enzymes. Bilirubin metabolism. Regulating glucose metabolism and the tests that characterise it.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Cardiovascular system. Cardiological markers. Lipid metabolism and homeostasis characteristics of cholesterol. Blood clotting characteristics - coagulogram. Assessment of the risk of thrombosis and bleeding.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Urinary system. Kidney tests, urine tests. Electrolytes. Acid-alkali balance.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Endocrine system. Thyroid hormones, sex hormones, stress hormones. Characteristics of hormone examination (in blood, urine).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Fundamentals of immunology. Lymphocyte subpopulations. Cytokines, immunoglobulins, antibodies, autoantibodies. Evaluation of allergic reaction.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Inflammation. Inflammatory markers. Oncomarkers. Genetic tests.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Diagnosis of infections. PCR tests, antigen tests, serological diagnostics, microbiological sampling.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Nervous system. Brain fluid examination.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Stool examinations. Cytological examinations. Sequencing.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Factors affecting the accuracy of laboratory tests. Examples of the use of biomarkers in biomedical research.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
24 Academic Hours
Final Examination:
Exam (Written)
PART-TIME
Part 1
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Urinary system. Kidney tests, urine tests. Electrolytes. Acid-alkali balance.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Endocrine system. Thyroid hormones, sex hormones, stress hormones. Characteristics of hormone examination (in blood, urine).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Endocrine system. Thyroid hormones, sex hormones, stress hormones. Characteristics of hormone examination (in blood, urine).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Fundamentals of immunology. Lymphocyte subpopulations. Cytokines, immunoglobulins, antibodies, autoantibodies. Evaluation of allergic reaction.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Inflammation. Inflammatory markers. Oncomarkers. Genetic tests.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Diagnosis of infections. PCR tests, antigen tests, serological diagnostics, microbiological sampling.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Diagnosis of infections. PCR tests, antigen tests, serological diagnostics, microbiological sampling.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Nervous system. Brain fluid examination.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Nervous system. Brain fluid examination.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Stool examinations. Cytological examinations. Sequencing.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Stool examinations. Cytological examinations. Sequencing.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
1
|
Topics
|
Factors affecting the accuracy of laboratory tests. Examples of the use of biomarkers in biomedical research.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
12 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Victor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kenelly, P. Anthony Weil. Harper’s Illustrated Biochemistry. 31st edition. Lange, 2022.Suitable for English stream
2.
Goldman L, Schafer AI. Goldman's Cecil Medicine. 25th Edition. Saunders, 2023.Suitable for English stream
3.
Chernecky Cynthia C., Berger Barbara J. Laboratory tests and diagnostic procedures. 6th edition. Elsevier, 2013. (akceptējams izdevums)Suitable for English stream
4.
McPherson, Richard A., Pincus, Matthew R. Henry’s. Clinical Diagnosis and Management by Laboratory Methods. 23rd edition. Elsevier, 2022.
Other Information Sources
1.
ClinicalkeySuitable for English stream
2.
WHOSuitable for English stream
3.
EbrarySuitable for English stream
4.
JmdSuitable for English stream
5.
MedscapeSuitable for English stream