Veidlapa Nr. M-3 (8)
Study Course Description
Medical Biochemistry
Course Code
CFUBK_087
Branch of Science
Clinical medicine
ECTS
6.00
Target Audience
Dentistry
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Kalvis Brangulis
Structure Unit Manager
Pēteris Tretjakovs
Structural Unit
Department of Human Physiology and Biochemistry
Contacts
Riga, 16 Dzirciema Street, cfbk@rsu.lv, +371 67061550
About Study Course
Objective
To gain the knowledge about the structural and functional features of the macromolecules found in the living organisms. To acquire the knowledge about the chemical reactions, interactions and main metabolic processes that occur within the human organism.
Preliminary Knowledge
Chemistry and biology at secondary school level.
Learning Outcomes
Knowledge
1.After the study course the student will be able to: • describe the function and structure of the main macromolecules found in the human organism; • describe the structure and function of proteins, including general knowledge about the mechanism of enzymes; • explain the enzymatic digestion processes in the human organism; • describe the main metabolic processes in the human organism; • describe and recognize the biochemical reactions of the main metabolic pathways.
Skills
1.After the study course the student will be able to use the acquired knowledge to: • describe and analyze the digestion process in the human organism; • analyze and evaluate the metabolism of carbohydrates, fats and proteins; • define the main metabolic processes and principles of bioenergetics, regulation; • describe the interconnections between different metabolic pathways.
Competences
1.The students will gain the necessary knowledge to understand what is necessary for biochemical processes to be fully operational and they will be able to analyze and discuss about the impact of various factors on the biochemical processes of the human organism.
Assessment
Individual work
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Title
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% from total grade
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Grade
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1.
Individual work |
-
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-
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Independently study the latest scientific literature and integrate it into the studying process. Independent preparation of the homework specified in the class protocols before the relevant seminar. Independently prepare/fill in class protocols. To make a presentation at the end of the course. Using the sources available in the e-studies and the mandatory literature specified in the e-studies to independently prepare for colloquiums and the exam.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
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Examination
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Examination |
-
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-
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• attendance of the practical classes;
• colloquiums in written form - during the study course there are 2 colloquia;
• final exam in written form.
• The final grade of the study course "Medical Biochemistry" consists of the cumulative assessment of the colloquia (50%) and the exam (50%).
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Study Course Theme Plan
FULL-TIME
Part 1
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Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Description of proteins. Enzymes: structure, influence of pH and T
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-
Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Enzymes: classification; mechanism of action; activity; specificity.
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-
Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Enzymes: activators and inhibitors. Digestion.
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Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Bioenergetics.
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Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Metabolism of Carbohydrates: glycolysis, anaerobic glycolysis; Cori cycle; oxidative decarboxylation.
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Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Krebs cycle; ETC; glycogenesis; glycogenolysis; gluconeogenesis; Pentose phosphate pathway.
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Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Metabolism of fats: oxidation and synthesis of fatty acids; ketogenesis.
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-
Video Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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Metabolism of amino acids. Urea cycle.
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Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Influence of T and pH on enzymes activity.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Specificity of enzymes.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Activity of enzymes, activators and inhibitors of enzymes.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Digestion of nutrients in human.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Colloquium: proteins; enzymes; digestion.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Bioenergetics.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Metabolism of Carbohydrates.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Metabolism of fats; ketogenesis.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Metabolism of amino acids.
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-
Class/Seminar
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Laboratory
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3
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Topics
|
Colloquium: metabolism of carbohydrates, fats and proteins.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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3
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Topics
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Seminar. Presentation.
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Total ECTS (Creditpoints):
6.00
Contact hours:
49 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Victor Rodwell, P. Anthony Weil, David Bender, Kathleen M. Botham, Peter J. Kennelly. Harper's Illustrated Biochemistry, 30th Edition, 2018.
2.
E-studijās ievietotie lekciju un nodarbību materiāli.
3.
Nelson, D., and Cox, M. Lehninger principles of biochemistry, 8th Edition, 2021 (vai jaunāka versija)
4.
Denise R. Ferrier. Lippincott Illustrated Reviews: Biochemistry, 6th Edition, 2017.
Additional Reading
1.
Devlin's Textbook of Biochemistry with Clinical Correlations. Martin D. Snider. John Wiley & Sons, Incorporated, 2024
2.
Marks' Basic Medical Biochemistry: A Clinical Approach. Michael A. Lieberman, Alisa Peet, Wolters Kluwer Health, 2022
Other Information Sources
1.
PUBMED datubāze.