Veidlapa Nr. M-3 (8)

Study Course Description

Preparation and Use of Blood and Clood Components

Main Study Course Information

Course Code

RTR_006

Branch of Science

Anatomy; Clinical medicine

ECTS

21.00

Target Audience

Medicine

LQF

Level 8

Study Course Implementer

Course Supervisor

Natālija Kanta

Residency Speciality

Speciality

Transfusiologist

Supervisor of Medical Speciality

Natālija Kanta

Contacts

About Study Course

Objective

To provide theoretical and practical skills according to the requirements of the profession, to prepare specialists for transfusiologists sertification in compliance with the Latvian legislation.

Learning Outcomes

Knowledge

1.Preparation of blood components. Compatibility tests for blood transfusion. Consultation general medical practitioner and other medical staff on current transfusion practices.

Skills

1.Ability to prepare blood and blood components. Ability to do immunohematological examination and compatibility testing. Ability to consult general medical practitioner and other medical staff on current transfusion practices. Ability to transfuse blood components.Patient Blood Management.

Competences

1.Finishing the course the students will have the necessary competence to work at blood establishment/ hospital blood bank/ immunohaematological laboratory, they will have good knowledge in Transfusion Medicine and approved medical technologies, if necessary they will be able to consult general medical practicioners and other medical staff on current transfusion practices.

Assessment

Individual work

Title	% from total grade	Grade
1. Individual work	-	-
Pedagogical work - preparation of lectures / presentations for donor education or transfusion practices. Participation in donor attraction and education (mass media, publications, etc.). Completion of study course evaluation questionnaires.

Examination

Title	% from total grade	Grade
1. Examination	-	-
A publication or presentation has been prepared. There were speeches in TV or radio.

Study Course Theme Plan

FULL-TIME

Part 1

Seminar

Modality	Location
On site	Specialized room

Topics

EP Directives, Cabinet of Ministers regulations and other normative documentation

Seminar

Modality	Location
On site	Specialized room

Topics

Hygiene and desinfection requirements for blood establishments

Seminar

Modality	Location
On site	Specialized room

Topics

Quality system in Blood service. Hemovigilance

Seminar

Modality	Location
On site	Specialized room

Topics

Donor attraction, promotion of donor movement. Donor selection. Donor information about blood and blood component donation process, donor's rights and obligations. Documentation and registration of donor's adverse events, notification procedure.

Seminar

Modality	Location
On site	Specialized room

Topics

Blood collection. Requirements for labeling and identification of blood samples. Traceability, storage, transportation. Preparation and modification of blood components. Preparation of cryoprecipitate. Automatic apheresis procedure.

Seminar

Modality	Location
On site	Specialized room

Topics

Selection and labeling of blood components. Storage, transportation, stock management of blood components. Irradiation of blood components.

Seminar

Modality	Location
On site	Specialized room

Topics

Hematological and immunohematological testing of blood samples.

Seminar

Modality	Location
On site	Specialized room

Topics

Serological and molecular testing (NAT) of viral markers. Risk of transmission of viral infectious diseases. Procedure for retrospective testing of donor blood samples.

Seminar

Modality	Location
On site	Specialized room

Topics

Quality control of blood components.

Seminar

Modality	Location
On site	Specialized room

Topics

Immune system. Immunological aspects of transfusion therapy. Erythrocyte antigens. Antibodies. Mechanism of immune response. Antigen-antibody interaction. ABO system, genetics. Determination of ABO system blood groups. Clinical significance of subgroups of anti-A1 antibodies. Aloimunization mechanism. Erythrocyte antigen systems. Special donor selection. Neonatal haemolytic disease: ABO, RH, etc. Prophylaxis with anti-D immunoglobulin.

Seminar

Modality	Location
On site	Specialized room

Topics

Adverse reactions associated with blood components transfusions.

Seminar

Modality	Location
On site	Specialized room

Topics

Quality assurance in laboratories. Requirements for acceptance and rejection of samples. Records and document management. Testing results reporting to donor.

Seminar

Modality	Location
On site	Specialized room

Topics

Types of blood components, indications, contraindications, advantages of use. Transfusion effectiveness criteria. Plasma derivates, indications for ude. Adverse reactions.

Seminar

Modality	Location
On site	Specialized room

Topics

Blood component transfusion medical technology. Patient blood management system

Total ECTS (Creditpoints):

21.00

Number of Residency Seminars:

Length (weeks):

Final Examination:

Residency exam (Theory and practice)

Bibliography

Required Reading

Mazjānis I., Tirāns E. Infekcijas slimības, Rokasgrāmata. 2. izd. Valmiera; 2006. latv.-1008 lpp.

Ņemceva G., Sisene I., Šteinerte A. Praktiskā transfuzioloģija. Rīga: Medicīnas apgāds; 2009., latv.-126 lpp.

Contreras M., ed. ABC of Transfusion. Chichester; Wiley-Blackwell; 2009, pp- 81

Daniels G., Bromilow I. Essential Guide to Blood Groups. Oxford: Blackwell; 2009., pp-97

Engelfriet C. P. Immunohaematology. Amsterdam: Sanquin; 2003.

Quinley E.D., Immunohematology. Principles & Practice. 3rd ed.- Lippincot Williams&Wilkins, 2011, pp- 411.

Guide to the preparation, use and quality assurance of blood components. 20th ed. Council of Europe; 2020., pp-436;

Hoffbrand A.V., Catovsky D., Tuddenham E. Postgraduate Haematology., 5th ed., Oxford: Blackwell; 2005, pp-1073;

Klein Harvey G. Mollison`s blood transfusion in clinical medicine. 11th ed. Oxford: Blackwell; 2005., pp- 891,

10.

Mintz P. D., ed. Transfusion therapy: clinical principles and practice. 2nd ed. Bethesda: AABB Press; 2005, pp-716;

11.

Murphy M. F., Pamphilon D. H. Practical transfusion medicine. 3rd ed. Oxford: Wiley-Blackwell; 2009. pp-366

12.

Rozentāle B., Dzenis J. Antimikrobiskās terapijas ceļvedis. Rīga: SIA Nacionālais medicīnas apgāds, 2004.

13.

Principles and Practice of Infectious Diseases. – 6th ed. – N.Y.: Mandell, Douglas & Bennett, 2007.

14.

ESH-EBMT Handbook on Haematopoietic Stem cell Transplantation. Ed. by Apperley J, Carreras E, Gluckman E, Gratwohl A, Masszi T. – Rev. ed. – European School of Haematology, 2008.

15.

Wintrobe’s Clinical Hematology. Ed. by Greer JP, Foerrester J, et al. – 12th ed. – Lippincott, William & Wilkins, 2009.

16.

Abbas AK, Lichtman AH, Baker DL. Basic Immunology: Functions and Disorders of the Immune System. – 3rd updated ed. – Saunders, 2010.

17.

Male D, Brostoff J, Roth DB, Roitt I. Immunology. – 7th ed. – Mosby, 2006.

18.

Turgeon ML. Immunology and serology in Laboratory Medicine. – 4th ed. – Mosby, 2008. pp-526

19.

Maitta, Robert W. Immunologic Concepts in Transfusion Medicine, 2020, pp-367

20.

Immunologic Concepts in Transfusion Medicine. Edited by Robert W.Maitta, 2020

Additional Reading

Transfusion medicine. Eds.:George P.Canellos, H.Franklin Bunn, 2019

Paula R.Howard. Blood Banking and Transfusion Practices. 5th ed., Elsevier, 2019, 420 lpp.

Vossoughi, Sarah R.,Stotler, Brie A. Topics in pediatric transfusion medicine. 2021, pp-171