Veidlapa Nr. M-3 (8)
Study Course Description
Microbiology
Course Code
BUMK_049
Branch of Science
Clinical medicine; Microbiology and Virology
ECTS
6.00
Target Audience
Pharmacy
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Ingus Skadiņš
Structure Unit Manager
Juta Kroiča
Structural Unit
Department of Biology and Microbiology
Contacts
Riga, 16 Dzirciema Street, bmk@rsu.lv, +371 67061584
About Study Course
Objective
To acquire knowledge about the spread, principles of classification, morphology, characteristics, methods for cultivation and identification of micro-organisms, fungi and viruses.
Preliminary Knowledge
In biology, anatomy, histology, biochemistry.
Learning Outcomes
Knowledge
1.After completing the study course, students will be able to describe micro-organisms and the most relevant human parasites, describe their prevalence in the environment, understand and explain their pathogenicity and role in the origin of infectious diseases and interaction processes with macro-organisms.
Skills
1.As a result of completing the study course, students will be able: • to investigate finished dosage forms; • to apply disinfection and sterilisation methods in the production process of pharmaceutical preparations; • to evaluate the aetiology of illnesses, sources of infection, transmission routes, pathogenesis, epidemiological hazard, prevention.
Competences
1.By combining theoretical knowledge with practical skills, students will have the opportunity to apply them in the form of a unified integrative understanding of the importance of bacterial and viral pathogenicity factors in the aetiology of the disease, and will be able to apply them to the mechanisms of pathogenesis and interaction with the host organism.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Students will independently prepare presentations for seminars on the immune response and hypersensitivity reactions, current agents of infectious diseases.
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Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
• regular attendance of classes, active participation in practical classes;
• successful completion of weekly tests and semester colloquia;
• assessment of independent learning;
• cumulative exam at the end of the study course, fulfilling all criteria. Detailed information in e-studies. It is possible to decline the cumulative assessment and take the exam. The exam consists of four open-ended questions.
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Study Course Theme Plan
FULL-TIME
Part 1
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Effect of physical, chemical and biological factors on micro-organisms. Sterilisation. Disinfection. Antibiotics, groups and mechanisms of action thereof. Development of resistance to antibiotic substances. Determining the susceptibility of micro-organisms to antibiotic substances.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Principles of microbiological and serological diagnostics of infectious diseases. Immune serums. Diagnostic kits. Types of agglutination reactions. Reactions with marked Ag and AV, ELISA, immunofluorescence, PCR.
Vaccines, types, principles of development and application thereof. Immune response and hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Principles of microbiological and serological diagnostics of infectious diseases. Immune serums. Diagnostic kits. Types of agglutination reactions. Reactions with marked Ag and AV, ELISA, immunofluorescence, PCR.
Vaccines, types, principles of development and application thereof. Immune response and hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Medicinal plants and microflora of finished dosage forms. Phytopathogenic microbes. Plating of microflora of air, human body and dosage forms and analysis of the results thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Introduction to microbiology. History of microbiology. Classification of micro-organisms. Morphology of bacteria. Atypical bacteria. Viruses. Fungi. Metabolism in bacteria. Human and environmental microflora. Factors affecting micro-organisms. Antibiotic substances. Resistance of micro-organisms to antibiotics.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Effect of physical, chemical and biological factors on micro-organisms. Sterilisation. Disinfection. Antibiotics, groups and mechanisms of action thereof. Development of resistance to antibiotic substances. Determining the susceptibility of micro-organisms to antibiotic substances.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Microscopic examination methods. Simple and differential staining methods. Microscopy technique. Culture media. Plating technique. Investigation of air microflora. Determination of human microflora. Plating to determine the microflora of dosage forms.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Microscopic examination methods. Simple and differential staining methods. Microscopy technique. Culture media. Plating technique. Investigation of air microflora. Determination of human microflora. Plating to determine the microflora of dosage forms.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Effect of physical, chemical and biological factors on micro-organisms. Sterilisation. Disinfection. Antibiotics, groups and mechanisms of action thereof. Development of resistance to antibiotic substances. Determining the susceptibility of micro-organisms to antibiotic substances.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Medicinal plants and microflora of finished dosage forms. Phytopathogenic microbes. Plating of microflora of air, human body and dosage forms and analysis of the results thereof.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Infection and immunity. Non-specific resistance factors: general, cellular, humoral.
Specific immunity. Antigens and antibodies. Immunocompetent cells. Immune response. Hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Principles of microbiological and serological diagnostics of infectious diseases. Immune serums. Diagnostic kits. Types of agglutination reactions. Reactions with marked Ag and AV, ELISA, immunofluorescence, PCR.
Vaccines, types, principles of development and application thereof. Immune response and hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Medicinal plants and microflora of finished dosage forms. Phytopathogenic microbes. Plating of microflora of air, human body and dosage forms and analysis of the results thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Infection and immunity. Non-specific resistance factors: general, cellular, humoral.
Specific immunity. Antigens and antibodies. Immunocompetent cells. Immune response. Hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Infection and immunity. Non-specific resistance factors: general, cellular, humoral.
Specific immunity. Antigens and antibodies. Immunocompetent cells. Immune response. Hypersensitivity.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Effect of physical, chemical and biological factors on micro-organisms. Sterilisation. Disinfection. Antibiotics, groups and mechanisms of action thereof. Development of resistance to antibiotic substances. Determining the susceptibility of micro-organisms to antibiotic substances.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Introduction to microbiology. History of microbiology. Classification of micro-organisms. Morphology of bacteria. Atypical bacteria. Viruses. Fungi. Metabolism in bacteria. Human and environmental microflora. Factors affecting micro-organisms. Antibiotic substances. Resistance of micro-organisms to antibiotics.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
32 Academic Hours
Final Examination:
Test (Semester)
Part 2
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Agents of respiratory viral infections (influenza, parainfluenza, epidemic parotitis, measles, rubella) – pathogenesis of infections, diagnostic principles and specific prevention.
Pathogenesis, diagnostic principles and specific prevention of adenovirus and herpesvirus infections.
Agents of enteroviruses (rotavirus, norovirus) and hepatitis (A, B, C, D), pathogenesis of infections, diagnostic principles, prevention.
Pathogenesis of neurotropic virus (tick-borne encephalitis) infections.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci.
Infections of the digestive tract. Intestinal bacteria, viral infections.
Infections of the respiratory system. Bacterial and viral infections.
Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Agents of respiratory viral infections (influenza, parainfluenza, epidemic parotitis, measles, rubella) – pathogenesis of infections, diagnostic principles and specific prevention.
Pathogenesis, diagnostic principles and specific prevention of adenovirus and herpesvirus infections.
Agents of enteroviruses (rotavirus, norovirus) and hepatitis (A, B, C, D), pathogenesis of infections, diagnostic principles, prevention.
Pathogenesis of neurotropic virus (tick-borne encephalitis) infections.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Tuberculosis – agents, properties thereof, mechanisms of pathogenesis, principles of microbiological diagnosis, prevention.
Spirochetoses (syphilis, Lyme disease), chlamydioses – agents, pathogenesis, microbiological diagnosis.
Infections caused by pathogenic fungi (dermatophytes and Candida albicans) and diagnostic principles thereof.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Tuberculosis – agents, properties thereof, mechanisms of pathogenesis, principles of microbiological diagnosis, prevention.
Spirochetoses (syphilis, Lyme disease), chlamydioses – agents, pathogenesis, microbiological diagnosis.
Infections caused by pathogenic fungi (dermatophytes and Candida albicans) and diagnostic principles thereof.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci.
Infections of the digestive tract. Intestinal bacteria, viral infections.
Infections of the respiratory system. Bacterial and viral infections.
Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci.
Infections of the digestive tract. Intestinal bacteria, viral infections.
Infections of the respiratory system. Bacterial and viral infections.
Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci.
Infections of the digestive tract. Intestinal bacteria, viral infections.
Infections of the respiratory system. Bacterial and viral infections.
Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Tuberculosis – agents, properties thereof, mechanisms of pathogenesis, principles of microbiological diagnosis, prevention.
Spirochetoses (syphilis, Lyme disease), chlamydioses – agents, pathogenesis, microbiological diagnosis.
Infections caused by pathogenic fungi (dermatophytes and Candida albicans) and diagnostic principles thereof.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Properties of E.coli and salmonella, staphylococci and streptococci (group A and S.pneumoniae), meningococci and gonococci, pathogenicity factors, pathogenesis, prevention. Principles of microbiological diagnosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Properties of E.coli and salmonella, staphylococci and streptococci (group A and S.pneumoniae), meningococci and gonococci, pathogenicity factors, pathogenesis, prevention. Principles of microbiological diagnosis.
|
-
Video Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Agents of respiratory viral infections (influenza, parainfluenza, epidemic parotitis, measles, rubella) – pathogenesis of infections, diagnostic principles and specific prevention.
Pathogenesis, diagnostic principles and specific prevention of adenovirus and herpesvirus infections.
Agents of enteroviruses (rotavirus, norovirus) and hepatitis (A, B, C, D), pathogenesis of infections, diagnostic principles, prevention.
Pathogenesis of neurotropic virus (tick-borne encephalitis) infections.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Wound infections and skin infections. The main group of bacterial, fungal and anaerobic infections, pathogenic cocci.
Infections of the digestive tract. Intestinal bacteria, viral infections.
Infections of the respiratory system. Bacterial and viral infections.
Transmissible (blood) infections. Hepatitis viruses. HIV/AIDS. Neurotropic viruses.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Properties of E.coli and salmonella, staphylococci and streptococci (group A and S.pneumoniae), meningococci and gonococci, pathogenicity factors, pathogenesis, prevention. Principles of microbiological diagnosis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Properties of E.coli and salmonella, staphylococci and streptococci (group A and S.pneumoniae), meningococci and gonococci, pathogenicity factors, pathogenesis, prevention. Principles of microbiological diagnosis.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
32 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Jawetz, Melnick, & Adelberg's Medical Microbiology. 27th ed., 2016.
2.
P. Murray, et al. Medical Microbiology. 8th ed. 2021.
Additional Reading
1.
Review of Medical Microbiology and Immunology. 17th ed., 2021
2.
Aija Žileviča, Ivars Mazjānis – Medicīnas mikrobioloģija. Vispārīgā mikrobioloģija un infekcijas imunoloģija. Latvijas Universitātes akadēmiskais apgāds; 2014
3.
Ārvalstu studentiem/For international students
4.
Review of Medical Microbiology and Immunology. 17th ed., 2021
Other Information Sources
1.
http://estudijas. rsu.lv.