Veidlapa Nr. M-3 (8)
Study Course Description
Histology
Course Code
MK_071
Branch of Science
Clinical medicine; Histology and Cytology
ECTS
10.00
Target Audience
Medicine
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Māra Pilmane
Structure Unit Manager
Māra Pilmane
Structural Unit
Department of Morphology
Contacts
Riga, 9 Kronvalda boulevard, aaiak@rsu.lv, +371 67061551
About Study Course
Objective
Students develop understanding of the main principles of general, special and functional human histology, structure of cells, tissue and organs; morphofunctional correlation between different tissue and organ structures, cell differentiation, regeneration, adaptation and ontogenetic changes; students develop skills in widely used light microscopy, immunohistochemical and electron microscopy methods; they develop understanding of the significance of morphology in daily clinical work; the students develop understanding of structure of different organs and systems, particularly morphofunctionality, differences and interactions between the endocrine, neural and immune systems.
Preliminary Knowledge
Medical cell biology, cytology; advisable to study histology simultaneously with biology, anatomy, physiology and biochemistry.
Learning Outcomes
Knowledge
1.On completion of the study course students will know and will be able to explain differences between general, special and functional histology. They will be able to interpret characteristic structural features of each tissue group and main organs; to describe differences between structures during ageing and adaptation processes. Students will be able to systematise morphological research methods and their use in daily work of a doctor.
Skills
1.On completion of the study course, students will be able to distinguish between the main tissue groups and the structure of the main organs in microscope and schemes; they will be able to describe and evaluate quality, information, interactions and localization of the visible tissue structures in histological slides; they will be able to record histological specimens and to obtain, assess, classify and compare information from the latest special literature and present histological schemes in the subject.
Competences
1.Upon combining theoretical knowledge and practical skills, the students will be able to implement them in an unified integrative diagnostic activity. Students will be able to recognize tissue and organ morphology and structure in clinical specimens and pictures of the science of morphology. They will be able to distinguish between healthy and pathological tissues. The students will be able to assess the quality of the specimen and the way they can be used for clinic.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Students do their independent learning when analysing the structure of histological slides in the laboratory and preparing the protocols of their practical work. Individual work with the recommended literature, according to the topic of lectures and practical classes. Preparation of small group presentations according to the topics of the course. Analysis of the results of scientific publications to raise awareness of the study course.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Regular attendance of practical classes.
Laboratory class protocols of appropriate quality and submitted in due time.
Colloquia include assessment of theoretical knowledge and practical skills acquired.
End-of-course oral examination testing students’ theoretical knowledge (50%) of tissue and organ morphology and practical skills (50%) in analysing specimens and schematic images. Students show how to specify age-related changes in tissues and organs. They demonstrate their understanding of important processes and functions in the tissues and organs and the ability to relate morphology with the processes.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Epithelia.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Connective tissue
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Nerve tissue. CNS.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Supportive tissue and development of bones.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Muscle tissue.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Blood.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Hemopoietic and immune organs.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Sense organs.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Cytology I: general organelles of the cell.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Cytology II: specialized cell organelles and inclusions.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Epithelia.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Connective tissue.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Nerve tissue and peripheral nervous system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Central nervous system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Colloquium I. Cytology. Epithelia. Connective tissue. Nerve tissue. PNS and CNS. Specimens of the practical works No. 1-6.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Supportive tissue: cartilage and bone.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Bone development.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Muscle tissue.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Blood vessels.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Blood. Haematopoiesis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Haematopoietic and immune organs. Immune system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Colloquium II. Supportive tissue: cartilage and bone. Bone development. Muscle tissue. Blood vessels. Blood, haematopoietic and immune organs. Specimens of the practical works No. 8-13.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Skin and its derivatives.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
2
|
Topics
|
Organ of vision. Eyeball.
|
Total ECTS (Creditpoints):
4.00
Contact hours:
48 Academic Hours
Final Examination:
Test (Semester)
Part 2
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Respiratory system.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Oral cavity. Tooth development and structure.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Digestive system structure: Stomach, small intestine, large intestine.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Gastrointestinal system digestive glands: Pancreas. Liver.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Reproductive system.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Neuroendocrine system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Organ of hearing. Anatomy of the ear.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Seminar: Skin and its derivatives. Sense organs – recognition of slides/analysis of mistakes (4 academic hours).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Respiratory system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Gastrointestinal system I.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Gastrointestinal system II.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Gastrointestinal system III.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Gastrointestinal system IV.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Gastrointestinal system V.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Colloquium III. Respiratory and gastrointestinal systems. Specimens of the practical works No. 3.-8.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Excretory system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Male reproductive system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Female reproductive system I.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Female reproductive system II.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Neuroendocrine system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Diffuse neuroendocrine system.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Colloquium IV. Excretory system. Reproductive system. Neuroendocrine system. Specimens of the practical works No. 10-15.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Other
|
3
|
Topics
|
Role of morphological diagnostic methods in the daily clinical doctor’s practice. Demonstration of most common mistakes of morphological diagnostic methods.
|
Total ECTS (Creditpoints):
6.00
Contact hours:
63 Academic Hours
Final Examination:
Exam (Oral)
Bibliography
Required Reading
1.
Dālmane, A. 2010. Histoloģija. LU Akad. apg. ISBN10: 9984770427, ISBN13: 9789984770420. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji.
2.
Groma V., Zalcmane V. 2012. Šūna: uzbūve, funkcijas, molekulārie pamati. RSU publ., 284 lpp. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji.
3.
Ross Michael H., Pawlina W. 2018. Histology: A Text and Atlas: With Correlated Cell and Molecular Biology. 8th Edition. LWW. 928 p. ISBN-10 :1496383427Suitable for English stream
4.
Eroschenko Victor P. 2017. Atlas of Histology with Functional Correlations. 13th Edition. LWW. 617 p. ISBN-10: 1496316762Suitable for English stream
5.
Kierszenbaum Abraham L., Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211Suitable for English stream
6.
Lowe J., Anderson P., Anderson S. 2025. Stevens & Lowe's Human Histology. 6th Edition. Elsevier. 440 p. ISBN: 9780323612807Suitable for English stream
7.
Mescher Anthony L. 2023. Junqueira's Basic Histology: Text and Atlas. 17th Edition. McGraw-Hill Education. 480 p. ISBN-10:1260462986Suitable for English stream
8.
Ovalle William K., Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. 568 p. ISBN-10:0323694640Suitable for English stream
9.
Suvarna Kim S., Layton Christopher, Bancroft John D. 2019. Bancroft's Theory and Practice of Histological Techniques. 8th Edition. Elsevier. 584 p.Suitable for English stream
10.
Gartner Leslie P. 2020. Textbook of Histology. 5th Edition. Elsevier. 704 p. ISBN: 9780323672726Suitable for English stream
Additional Reading
1.
Dongmei Cui; John P. Naftel; Jonathan D. Fratkin; William Daley; James C. Lynch; Duane E. Haines; Gongchao Yang. 2011. Atlas of Histology with Functional and Clinical Correlations. LWW. 434 p. ISBN-10: 0781797594, ISBN-13: 978-0781797597. Precīzs un unikāls histoloģisko struktūru attainojums, nav atkārtota izdevuma.Suitable for English stream
2.
Gartner Leslie P. 2015. BRS Cell Biology and Histology. 8th Edition. Wolters Kluwer Health. 448 p. ISBN-13: 978-1496396358, ISBN-10: 1496396359Suitable for English stream
3.
Gartner Leslie P., Lee Lisa M. J. 2022. Gartner & Hiatt's Atlas and Text of Histology. 8th Edition. LWW. 648 p. ISBN-13: 978-1975164256, ISBN-10: 1975164253Suitable for English stream
4.
Hossler Fred. 2014. Ultrastructure Atlas of Human Tissues. 1st Edition. Wiley-Blackwell. 968 p. ISBN-10: 1118284534, ISBN-13: 978-1118284537Suitable for English stream
5.
Ovalle William K., Nahirney Patrick C. 2020. Netter’s Histology Cut-Out Flash Cards: A companion to Netter's Essential Histology. 2nd Edition. Elsevier. 136 p. ISBN-13: 978-0323709675, ISBN-10: 0323709672Suitable for English stream
6.
Nanci A. 2013. Ten Cate's Oral Histology: Development, Structure, and Function. 9th Edition. Elsevier. 352 p. ISBN-13: 978-0323485241, ISBN-10: 0323485243Suitable for English stream
7.
Young Barbara, O'Dowd Geraldine, Woodford Phillip. 2023. Wheater's Functional Histology: A Text and Colour Atlas. 7th Edition. Churchill Livingstone. 464 p. ISBN-10: 0702047473, ISBN-13: 978-0702047473Suitable for English stream
8.
Zhang Guiyun, Fenderson Bruce A. 2014. Lippincott's Illustrated Q&A Review of Histology. LWW. 360 p. ISBN-10: 1451188307, ISBN-13: 978-1451188301Suitable for English stream
9.
Gartner Leslie P. Color Atlas and Text of Histology. 2014. 7th edition. LWW. ISBN13: 9781496346735, ISBN10: 1496346734Suitable for English stream
Other Information Sources
1.
Department of Biochemistry and Molecular BiologySuitable for English stream
2.
Meddean.lucSuitable for English stream
3.
Histology guideSuitable for English stream