Veidlapa Nr. M-3 (8)
Study Course Description

Medical Chemistry

Main Study Course Information

Course Code
CFUBK_073
Branch of Science
Chemical sciences; Medical Chemistry
ECTS
6.00
Target Audience
Medicine
LQF
Level 7
Study Type And Form
Full-Time

Study Course Implementer

Course Supervisor
Structure Unit Manager
Structural Unit
Department of Human Physiology and Biochemistry
Contacts

Riga, 16 Dzirciema Street, cfbk@rsu.lv, +371 67061550

About Study Course

Objective

Provide an introduction into various chemical processes happening in human body, medicine and related fields. Promote the understanding of properties, functions and usage of various medication and chemical agents. Improve practical and experimental skills dealing with various common research equipment, experimental data interpretation. Provide basics for further studies of biochemical processes in the human body.

Preliminary Knowledge

Basic knowledge of secondary school programme chemistry, physics and mathematics.

Learning Outcomes

Knowledge

1.Knowledge and understanding. Students will (according to the course topics): 1. Demonstrate knowledge and understanding of facts, concepts, and terminology (solutions, colligative properties, osmosis, oxidation process in inorganic and organic environment, kinetics and equilibrium, acid-base theories, pH and buffer solutions). 2. Apply methodologies and techniques. Use and develop an understanding of the techniques and methodologies used in medical chemistry both in obtaining and processing results and in explaining different processes (for example, kinetics and equilibrium). 3. Understand the role of scientific information.

Skills

1.Application. Analysis and synthesis. When explaining processes and regularities students will be able to: 1. Apply and analyse facts, concepts, and terminology of medical chemistry in new situations and different ways. 2. Analyse, compare and evaluate methodologies and techniques used in medical chemistry. 3. Improve their skills in using and analysing methods for transferring scientific information: a. use problem-solving skills. Improve skills in examining and solving cases. b. Improve their skills in using scientific literature as a source of information. c. Assess and apply safe work methods in the laboratory. d. Use communication skills gained in organised group work.

Competences

1.On completion of the course students will be able to apply the acquired knowledge and skills of the diverse processes of general and inorganic chemistry and the mechanisms of chemical reactions; predict their impact on human homeostasis; use the skills acquired in laboratory work – to prepare, to conduct an experiment, to use appropriate devices and equipment, to evaluate the results – for further practical or scientific work; will develop the ability to integrate knowledge of medical chemistry as part of the overall knowledge of the human body.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Independent work (self-studies) in the course include: • independent study of the materials offered in e-studies (video, animation, reading of literature, learning of terms and definitions, etc.) and study of each subsequent lesson according to the study guide; • getting self-assessment (tests, self-control tests, reflection exercises on video-lectures); • preparation of laboratory work protocols; • preparation for tests according to the program published on e-studies.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
The final grade of the course is cumulative. It is compiled of pre- and post- lab tests (in total 10% of final course grade), colloquiums (50%), final presentation preparation about the topics covered in the course (10%) and final summary test covering the whole course content (30%).

Study Course Theme Plan

FULL-TIME
Part 1
  1. Class/Seminar

Modality
Location
Contact hours
Off site
E-Studies platform
4

Topics

Calculations and graphical methods in chemistry
Description
Annotation: Seminar. Concentration calculations (molar, mass percent, mass), interconverting concentrations, dilution. Stoichiometry calculations Topics covered during the class: 1. Solutions, the composition of solutions. Electrolytes and non - electrolytes. 2. Types of concentrations. Formulas for their calculation. 3. Methods for preparing the solutions. 4. Solutions in medicine, expression of their concentrations. 5. Comparing concentrations, converting them from one type to another. 6. Dilution of solutions. Calculations and dilution methods. 7. Stoichiometry. Calculations using molecular, ionic and net ionic equations
  1. Class/Seminar

Modality
Location
Contact hours
On site
Computer room
4

Topics

Colloquium No 2
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Oxidation – reduction processes. Complex problem analysis
  1. Video Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
1

Topics

Equilibrium processes in biological systems (osmosis, acids, bases, buffers, solubility, and coordinate compounds)
  1. Class/Seminar

Modality
Location
Contact hours
On site
Computer room
4

Topics

Colloquium No 1
  1. Class/Seminar

Modality
Location
Contact hours
Off site
E-Studies platform
4

Topics

Thermodynamics and its examples in biological systems
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Seminar. pH calculations. Colligative properties of solutions and osmosis.
  1. Class/Seminar

Modality
Location
Contact hours
Off site
E-Studies platform
4

Topics

Solutions and concentration calculation
Description
Annotation: The lecture is dedicated to the analytical methods used in chemistry and their application in medicine. In laboratory work, two methods of analysis are practically considered: spectrophotometry and titration, their use in the determination of the quantitative composition of the solution. Topics covered during the class: 1. Commonly used analysis methods in chemistry and medical laboratory chemistry. 2. Basic principles of the titration method: equipment, application of the method, limitations, detection limits. 3. Basic principles of spectrophotometric method: equipment, application of the method, limitations, detection limits. 4. Data acquisition and processing methods.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Chemical equilibrium and coordination compounds in biological systems
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

pH and buffer system calculations
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Methods of analysis in chemistry and their application in medicine
  1. Video Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
1

Topics

Seminar. pH calculations. Colligative properties of solutions and osmosis.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Buffer solutions and systems ir human organism
  1. Class/Seminar

Modality
Location
Contact hours
Off site
E-Studies platform
4

Topics

Introduction. Solutions and chemical reactions
Description
Annotation: Topics covered in the lecture. Solutions. Solutions in medicine. Electrolytes and non-electrolytes, ion formation. Concentration, concentration types, and calculations. Stoichiometry and its use in calculations based on chemical reaction equations and ion equations. Types of chemical reactions and their context in medicine. Topics covered during the class: Lab work. Safe working methods and safety in the chemistry laboratory. Laboratory equipment and accessories. Importance of significant digits in measurements and calculations.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Presentations on topic “Chemistry of …”. Problēmu analīze
  1. Video Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
1

Topics

Acids, bases and buffers in living systems
  1. Class/Seminar

Modality
Location
Contact hours
Off site
E-Studies platform
4

Topics

Kinetics and its role in biological systems
  1. Class/Seminar

Modality
Location
Contact hours
On site
Laboratory
4

Topics

Acid – Base titration
  1. Video Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
1

Topics

Introduction. Solutions and chemical reactions
Description
Annotation: Topics covered in the lecture. Solutions. Solutions in medicine. Electrolytes and non-electrolytes, ion formation. Concentration, concentration types, and calculations. Stoichiometry and its use in calculations based on chemical reaction equations and ion equations. Types of chemical reactions and their context in medicine. Topics covered during the class: Lab work. Safe working methods and safety in the chemistry laboratory. Laboratory equipment and accessories. Importance of significant digits in measurements and calculations.
Total ECTS (Creditpoints):
6.00
Contact hours:
64 Academic Hours
Final Examination:
Exam (Written)

Bibliography

Required Reading

1.

Chang, R. General Chemistry : the essential concepts / Boston: 2014 (akcpetējams izdevums)Suitable for English stream

2.

I.Kazuša. "Vispārīgā ķīmija medicīniskās ķīmijas kursam": mācību līdzeklis. Cilvēka fizioloģijas un bioķīmijas katedra. Rīga: Rīgas Stradiņa universitāte, 2021

Additional Reading

1.

Bishop, M. An Introduction to Chemistry - Atoms FirstSuitable for English stream

2.

Andrejs Rauhvargers. "Vispārīgā ķīmija", 1996

Other Information Sources

1.

LibreTexts "Chemistry"Suitable for English stream

2.

Charles Ophardt. "Virual Chembook", 2003Suitable for English stream

3.

Steve Lower. "Chem1 virtual textbook"Suitable for English stream

4.

Khan AcademySuitable for English stream