Veidlapa Nr. M-3 (8)

Study Course Description

Lymphomas

Main Study Course Information

Course Code

RHE_039

Branch of Science

Clinical medicine

ECTS

4.05

Target Audience

Medicine

LQF

Level 8

Study Course Implementer

Course Supervisor

Sandra Lejniece

Residency Speciality

Speciality

Hematologist

Supervisor of Medical Speciality

Sandra Lejniece

Contacts

About Study Course

Objective

Learning Outcomes

Knowledge

1.-

Skills

1.-

Competences

1.-

Assessment

Individual work

Title	% from total grade	Grade
1. Individual work	-	-

Examination

Title	% from total grade	Grade
1. Examination	-	-

Study Course Theme Plan

FULL-TIME

Part 1

Seminar

Modality	Location
-	-

Topics

Seminar

Modality	Location
-	-

Topics

Seminar

Modality	Location
-	-

Topics

Total ECTS (Creditpoints):

4.05

Number of Residency Seminars:

Length (weeks):

Final Examination:

Residency exam (Theory and practice)

Bibliography

Required Reading

Swerdlow S.H. et al The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood, 2016, 127 (20):2375-2390.

Barrington SF, Mikhaeel NG, Kostakoglu L et al. Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol 2014; 32: 3048–3058.

NCCN Clinical Practice Guidelines in Oncology: Hodgkin Lymphoma. National Comprehensive Cancer Network. Available at http://www.nccn.org/professionals/physician_gls/pdf/hodgkins.pdf. Version 1.2018 — December 20, 2017.

Eichenauer DA, Aleman BMP, André M, Federico M, Hutchings M, Illidge T, et al. Hodgkin lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018 (Supplement 4): iv19–iv29, 2018 doi:10.1093/annonc/mdy080 Published online 23 May 2018

Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016; 127, (20), 2375-2390.

Juarez-Salcedo LM, Sokol L, Chavez J, Dalia A. Primary Gastric Lymphoma, epidemiology, clinical diagnosis, and treatment. Cancer Control. 2018;25: 1-12.

Fox CP, Phillips EH, Smith J, Linton K, Gallop-Evans E et al. Guidelines for the diagnosis and management of primary central nervous system diffuse large B-cell lymphoma. British Journal of Haematology, 2019, 184, 348-363.

H. Tilly, M. Gomes da Silva, U. Vitolo, A. Jack, M. Meignan, A. Lopez-Guillermo, J. Walewski, M. André, P. W. Johnson, M. Pfreundschuh and M. Ladetto, on behalf of the ESMO Guidelines Committee. Diffuse large B-cell lymphoma (DLBCL): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology 26 (Supplement 5): v116–v125, 2015 doi:10.1093/annonc/mdv304

E. Zucca, L. Arcaini, C. Buske, P.W. Johnson, M. Ponzoni, M. Raderer, U. Ricardi, A. Salar, K. Stamatopoulos, C. Thieblemont, A. Wotherspoon, M. Ladetto.Marginal zone lymphomas: ESMO Clinical Practice Guidelines. Ann Oncol (2020); 31(1): 17-29.

10.

Dreyling M., Ghielmini M., Marcus R., Vitolo U., Ladetto M. Newly diagnosed and relapsed follicular lymphoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Haematoloical Malignancies 2014, 25 Sppl 3, 76-82

11.

Sehn LH, Berry B, Chhanabhai M, Fitzgerald C, Gill K, Hoskins P, Klasa R, Savage KJ, Shenkier T, Sutherland J, Gascoyne RD, Connors JM. The revised International Prognostic Index (R-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP. Blood. 2007 Mar 1;109(5):1857-61.

12.

Solal-Celigny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R et al. Follicular Lymphoma International Prognostic Index Blood (2004) 104 (5): 1258–1265.

13.

Federico M, Bellei M, Marcheselli L, Luminari S, Lopez-Guillermo A, Vitolo U et al. Follicular Lymphoma International Prognostic Index 2: A New Prognostic Index for Follicular Lymphoma Developed by the International Follicular Lymphoma Prognostic Factor Project DOI: 10.1200/JCO.2008.21.3991 Journal of Clinical Oncology 27, no. 27 (September 20, 2009) 4555-4562.

14.

Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, Lister TA; Alliance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium; Italian Lymphoma Foundation; European Organisation for Research; Treatment of Cancer/Dutch Hemato-Oncology Group; Grupo Español de Médula Ósea; German High-Grade Lymphoma Study Group; German Hodgkin's Study Group; Japanese Lymphorra Study Group; Lymphoma Study Association; NCIC Clini

15.

Zaucha JM, Chauvie S, Zaucha R, Biggii A, Gallamini A. The role of PET/CT in the modern treatment of Hodgkin lymphoma. Cancer Treat Rev. 2019 Jul;77:44-56. doi: 10.1016/j.ctrv.2019.06.002. Epub 2019 Jun 19. PMID: 31260900.

16.

Cheson BD. PET/CT in Lymphoma: Current Overview and Future Directions. Semin Nucl Med. 2018 Jan;48(1):76-81. doi: 10.1053/j.semnuclmed.2017.09.007. Epub 2017 Oct 2. PMID: 29195620.

17.

Jain AG, Chang CC, Ahmad S, Mori S. Leukemic Non-nodal Mantle Cell Lymphoma: Diagnosis and Treatment. Curr Treat Options Oncol. 2019 Nov 27;20(12):85. doi: 10.1007/s11864-019-0684-8. PMID: 31776787.

18.

Dada R. Diagnosis and management of follicular lymphoma: A comprehensive review. Eur J Haematol. 2019 Sep;103(3):152-163. doi: 10.1111/ejh.13271. Epub 2019 Jul 4. PMID: 31270855.

Additional Reading

S.Lejniece. Klīniskā hematoloģija. Medicīnas Apgāds, 2020.

Alla Rivkina. Plūsmas citometrijas metode hematoloģisko slimību diagnostikā. SIA Medicīnas apgāds, 2019

Klīnisko analīžu rokasgrāmata. E.Gulbja laboratorija. Izdevējs E.Gulbja laboratorija, 2019.

Trotman J, Barrington SF. The role of PET in first-line treatment of Hodgkin lymphoma. Lancet Haematol. 2021 Jan;8(1):e67-e79. doi: 10.1016/S2352-3026(20)30357-4. Epub 2020 Dec 22. PMID: 33357485.

Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, Jaffe ES. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood. 2019 Apr 18;133(16):1703-1714. doi: 10.1182/blood-2018-11-881268. Epub 2019 Jan 11. Erratum in: Blood. 2019 Sep 26;134(13):1112. PMID: 30635287; ID: PMC6473500.

Ferry JA. Scientific Advances and the Evolution of Diagnosis, Subclassification and Treatment of Lymphoma. Arch Med Res. 2020 Nov;51(8):749-764. doi: 10.1016/j.arcmed.2020.05.022. Epub 2020 Jun 14. PMID: 32553461.

Goyal A, LeBlanc RE, Carter JB. Cutaneous B-Cell Lymphoma. Hematol Oncol Clin North Am. 2019 Feb;33(1):149-161. doi: 10.1016/j.hoc.2018.08.006. PMID: 30497672.

Ikoma N, Badgwell BD, Mansfield PF. Multimodality Treatment of Gastric Lymphoma. Surg Clin North Am. 2017 Apr;97(2):405-420. doi: 10.1016/j.suc.2016.11.012. Epub 2017 Feb 14. PMID: 28325194.

Zahid U, Akbar F, Amaraneni A, Husnain M, Chan O, Riaz IB, McBride A, Iftikhar A, Anwer F. A Review of Autologous Stem Cell Transplantation in Lymphoma. Curr Hematol Malig Rep. 2017 Jun;12(3):217-226. doi: 10.1007/s11899-017-0382-1. PMID: 28478586; PMCID: PMC5607634.

10.

Miralles P, Navarro JT, Berenguer J, Gómez Codina J, Kwon M, Serrano D, Díez-Martín JL, Villà S, Rubio R, Menárguez J, Ribera Santasusana JM. GESIDA/PETHEMA recommendations on the diagnosis and treatment of lymphomas in patients infected by the human immunodeficiency virus. Med Clin (Barc). 2018 Jul 13;151(1):39.e1-39.e17. English, Spanish. doi: 10.1016/j.medcli.2017.11.037. Epub 2018 Jan 19. PMID: 29357988.

11.

Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 2016; 127:2391-2405. https://doi.org/10.1182/blood-2016-03-643544

12.

Emile JF, Abla O, Fraitag S, et al. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood 2016; 127:2672.