Veidlapa Nr. M-3 (8)
Study Course Description
Chemotherapy in Gynecological Oncology and Breast Oncology
Course Code
ROG_002
Branch of Science
Clinical medicine; Obstetrics and gynaecology
ECTS
10.05
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Dace Rezeberga
Residency Speciality
Speciality
Gynaecological Oncologist
Supervisor of Medical Speciality
Dace Rezeberga
Contacts
-
About Study Course
Objective
To provide knowledge and competence in the use of chemotherapy at the level it is necessary to gynecological and breast cancer diagnosis and treatment.
Learning Outcomes
Knowledge
1.The most frequently used chemotherapeutic pharmacological characteristics, the latest research results on the use of preparations used in chemotherapy, cell biology, including cell cycle kinetics, cycle and phase specificity. Chemotherapeutic preparations classification and their mechanisms of action. Dose calculation principles. Advantages and disadvantages of the use of one preparation and simultaneous use of several preparations. Guidelines and recommendations for the evaluation of chemotherapeutic effect.
Skills
1.Chemotherapy Designation of gynecological oncology and breast oncology disease management complex, Neo-adjuvant and adjuvant chemotherapy, general and preparations specific toxicity of chemotherapy in short-term and long-term chemotherapy, use of chemotherapy in gestational trofoblasitc disease. The role of hormonal therapy in the treatment of gynecological cancers. I, II and Phase III clinical trial principles, involvement in clinical trials of the chemical preparation.
Competences
1.The ability to assign chemotherapy for gynecological and breast cancer cases, analyze the results of treatment and side-effects of chemotherapy, to make evidence-based views of chemotherapy for patients with evidence of genital or breast cancer based on tumor stage, histological findings.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Preparation of the matherials for patient presentation in multidisciplinary council.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Solving a clinical situation task with evaluation.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Seminar
|
Modality
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Location
|
|
|---|---|---|
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On site
|
Specialized room
|
Topics
|
Basic principles of systemic therapy (cytostatics, hormone therapy, target therapy), indications, mechanisms of action of the most commonly used groups of drugs and their side effects in the treatment of gynecological malignancies.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Use of chemotherapy in breast cancer treatment. Classes of chemotherapeutic tools and their mechanism of action,indications.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Radiation and chemotherapy of cervical cancer- indications, most common side effects and therapy. Chemotherapy in the treatment of metastatic cervix.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Intraperitoneal hyperthermic chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy (EPIC) principles and applications
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
The role of target therapy, immunotherapy, PARP inhibitors in the treatment of gynecological malignancies
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Chemotherapy and hormone therapy in the treatment of endometrial cancer.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Ovarian cancer systemic therapy: indications, medications and combinations; prevention of side effects and therapy.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Medication applied for gynecological cancer therapy characteristics, pharmacodynamics, the dose calculation and injection schemes.
|
Total ECTS (Creditpoints):
10.05
Number of Residency Seminars:
8
Length (weeks):
8
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Ayhan A., Reed N., Gultekin M., Dursun P. Textbook of gynecological oncology. - Turkey: Gunes publishing, 2016. - 1638 lpp
Additional Reading
1.
Chang A.E., Ganz P.A., Hayes D.F. Oncology. An Evidence Based Approach. - New York: Springer Science-Business Media Inc., 2006. - 675 lpp.
2.
Harris J.R., Lippman M.E., Morrow M., C. Osborne K. Diseases of the Breast. 4th Edition. - Philadelphia: Lippincott Williams & Wilkins. 2009. - 1200 lpp.
3.
Malcolm R.A. The Cancer Handbook. 2nd edition. – United Kingdom: Wiley, 2007. - 1772 lpp.
4.
Reed N., Green J.A., Gershenson D.M., Siddiqui N. Rare and Uncommon Gynecological Cancers: A Clinical Guide. - New York: Springer Science-Business Media Inc., 2010. - 200 lpp.
5.
Wilson J., Hunt T. Molecular Biology of the Cell. 5th Edition. - United Kingdom: Taylor & Francis, 2007. - 1392 lpp.
Other Information Sources
1.
Lekciju materiāls, semināru materiāls
2.
- www.esgo.com resursi reģistrētiem lietotājiem
3.
- LV reģistrētās vadlīnijas: Klīniskās vadlīnijas onkoloģijas ginekoloģisko saslimšanu diagnostikai, stadijas noteikšanai, ārstēšanai un novērošanai (2012), Dzemdes kakla vēža (C53) diagnostika, stadijas noteikšana, ārstēšana un novērošana (2013), Krūts vēža (C50, D05) diagnostika, stadijas noteikšana, ārstēšana un novērošana (2014) u.c.