Veidlapa Nr. M-3 (8)
Study Course Description
Pharmaceutical Biochemistry and Interpretation of Biochemical Tests
Course Code
CFUBK_027
Branch of Science
Basic medicine
ECTS
3.00
Target Audience
Pharmacy
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Ināra Nokalna
Structure Unit Manager
Pēteris Tretjakovs
Structural Unit
Department of Human Physiology and Biochemistry
Contacts
Riga, 16 Dzirciema Street, cfbk@rsu.lv, +371 67061550
About Study Course
Objective
Promote the acquisition of knowledge about the detoxification processes taking place in human body; importance of biochemical indicators used in diagnostics.
Preliminary Knowledge
Medical biochemistry and normal physiology of FF 2nd and 3rd course level.
Learning Outcomes
Knowledge
1.After successful completion of the course the student will be able to: • tell about the role of cytochrome P450 in metabolism, principle of operation; • define conjugated molecule formation and the role of in metabolism; • describe the main detoxification processes in the body; • interpret diagnostic biochemical parameters.
Skills
1.Will be able to explain: • Xenobiotics development chances in the body; • Cytochrome P 450 operating principles; • Conjugated molecule formation processes and the role of in detoxification. Will be able to evaluate detoxification process and differences in various organs. Will be able to evaluate the diagnostic significance of biochemical indicators.
Competences
1.The student will not be able to apply the acquired knowledge about ongoing body detoxification processes; their integration and regulation. Will be able to understand the biochemical diagnostic indicators.
Assessment
Individual work
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Individual work |
-
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-
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Independent learning of theoretical topics through sources, such as scientific books, publications.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
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Examination
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Title
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% from total grade
|
Grade
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|---|---|---|
|
1.
Examination |
-
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-
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|
• Participation in practical classes, problem solving (50%).
• At the final examination, is a presentation of a scientific work on the given study course (50%).
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Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Enzymes, principle of operation, influencing factors, operational regulation options. Medication principle of operation.
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-
Lecture
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
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Auditorium
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3
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Topics
|
Function of cytochrome P 450.
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-
Lecture
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Conjugating substances, their formation, role. Enzymes.
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-
Lecture
|
Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Amino acids as conjugating substances.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Interpretation of biochemical analysis - blood counts.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Interpretation of biochemical analysis - biochemical values.
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-
Class/Seminar
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Modality
|
Location
|
Contact hours
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|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Blood count
Nitrogen metabolism indicators.
Enzymes in diagnostics.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
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|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Presentation of research paper.
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Total ECTS (Creditpoints):
3.00
Contact hours:
24 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Sandra Lejniece. Klīniskā hematoloģija. Medicīnas apgāds, 2020
2.
V.W.. Rodwell, D.A. Bender, P.J. Kennelly, P.A. Weil. Harper's Illustrated Biochemistry. 31st ed., 2018. by Appleton & Lange, Stamford, CT. 807.
3.
A. Balode. Laboratoriskā diagnostika. Nacionālais apgāds, 2008 (akceptējams izdevums)
Additional Reading
1.
R.A. Harvey, D.R. Ferrier. Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews Series), 2021: 544.
2.
Klīnisko analīžu rokasgrāmata E. Gulbja laboratorija, 2018
Other Information Sources
1.
Pub Med un citas datu bāzes.