Clinical Pharmacology and Pharmacologically Assisted Care
Study Course Implementer
Konsula iela 21, 2nd floor, room 210, Riga, LV-1007, linda.rugele@rsu.lv, tel. +37167409213
About Study Course
Objective
According to the needs of the specialty to be studied, to promote students' ability to orient themselves in the pharmacotherapy of the most frequent chronic diseases and acute conditions. To provide knowledge about the most characteristic side effects and contraindications, taking into account the choice of the method of administration.
Preliminary Knowledge
Basic physiology, understanding of the principles of pharmacological treatment of the most common diseases.
Learning Outcomes
Knowledge
1.Knows the mechanisms of action, indications, contraindications of the most commonly used pharmacological groups
Colloquium I • Colloquium II • Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination
2.Knows the most important side effects of commonly used drugs
Examination • Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Colloquium II • Colloquium I
3.Understand the role of pharmacokinetics and pharmacodynamics in the evaluation of drug efficacy and safety
Colloquium I • Examination
4.Understand clinically relevant drug interactions and their potential impact on therapeutic outcomes
Examination • Colloquium I • Colloquium II
5.Understands the principles of adjusting drug doses according to the age of the patient, kidney and liver function, comorbidities and other individual factors
Colloquium II • Colloquium I • Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination
Skills
1.Recognise the most common and clinically significant adverse drug reactions
Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination • Colloquium II
2.Identify potential drug interactions and other medication-related risks
Colloquium I • Examination • Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice
3.Interpret clinical and laboratory parameters relevant to therapy monitoring
Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination • Colloquium II
4.Provide the patient with understandable information about the correct use of the medication, possible side effects and the importance of adherence
Colloquium II • Examination • Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice
5.Calculate the required dose of medication, time of administration
Colloquium II • Colloquium I • Examination
Competences
1.To analyse the medications indicated in the anamnesis and prescriptions according to the expected clinical effect, to assess their therapeutic effectiveness and the development of side effects
Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination
2.Assess the appropriateness of prescribed doses and rates of administration of high-risk medications.
Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice • Examination • Colloquium II
3.To contribute to the reduction of risks of medication errors, administration and inappropriate prescription.
Colloquium I • Examination
4.Educate patients on the correct use of the medicinal product, its indications and adverse reactions.
Examination • Colloquium I
5.Explain the meaning and therapeutic effectiveness of the medication in language that the patient can understand.
Colloquium II • Examination
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
Test
|
|
Performing self-assessment tasks, active participation in discussion and analysis of tasks, clinical situations. Providing course evaluation. |
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Colloquium I |
30.00% from total grade
|
10 points
|
|
30-question test consisting of multiple-choice questions, clinical case studies and calculation tasks in varying proportions. |
||
|
2.
Colloquium II |
30.00% from total grade
|
10 points
|
|
30-question test consisting of multiple-choice questions, clinical case studies and calculation tasks in varying proportions. |
||
|
3.
Defence of the evaluation of pharmacotherapy of the clinical case selected within the framework of clinical practice |
40.00% from total grade
|
10 points
|
|
At the end of the study course, on the scheduled dates, each student must carry out a pharmacotherapy evaluation for their chosen clinical case, defending it at the same time as the clinical placement. |
||
|
4.
Examination |
-
|
10 points
|
|
In the study course, an accumulated exam grade is awarded regardless of the value obtained if a positive grade is obtained during the first time of taking interim examinations and clinical case pharmacotherapy evaluation and defence. 60% of the average grade of both colloquia taken + 40% of the grade of the clinical case pharmacotherapy analysis (taking into account both the submitted evaluation protocol and the defence) If the criteria for first-time successful completion of interim examinations and defence are not met, a 30-question examination must be taken, which is implemented as a separate event (examination work). In this case, the final grade is calculated as a summative exam: 50% of the cumulative grade + 50% of the examination work grade. |
||
Study Course Theme Plan
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Basic principles of antihypertensive therapy.
|
|
Medications used in the management of hypertensive crisis.
|
|
Basic principles of therapy for coronary heart disease.
|
|
Pharmacotherapy of acute coronary syndrome.
|
|
Pharmacology of the digestive system
|
|
Drugs used in the management of cardiogenic shock.
|
|
Hypolipidemic therapy.
|
|
Anti-thrombotic therapy.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Basic principles of asthma therapy.
|
|
Asthma attack management.
|
|
Principles of treatment of chronic obstructive pulmonary disease.
|
|
Principles of respiratory infection management.
|
|
Characteristics and use of anti-allergic agents.
|
|
Management of anaphylactic shock.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Basic principles of gastroesophageal reflux disease treatment.
|
|
Prevention and treatment of vomiting.
|
|
Managment of constipation.
|
|
Management of gastroenteritis.
|
|
Principles of treatment of Clostridium difficile colitis.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Management of type 1 diabetes mellitus. Treatment of gestational diabetes.
|
|
Management of type 2 diabetes.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Pain management.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Basic principles of antihypertensive therapy.
|
|
Medications used in the management of hypertensive crisis.
|
|
Basic principles of therapy for coronary heart disease.
|
|
Pharmacotherapy of acute coronary syndrome.
|
|
Pharmacology of the digestive system
|
|
Drugs used in the management of cardiogenic shock.
|
|
Hypolipidemic therapy.
|
|
Anti-thrombotic therapy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Basic principles of asthma therapy.
|
|
Asthma attack management.
|
|
Principles of treatment of chronic obstructive pulmonary disease.
|
|
Principles of respiratory infection management.
|
|
Characteristics and use of anti-allergic agents.
|
|
Management of anaphylactic shock.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Basic principles of gastroesophageal reflux disease treatment.
|
|
Prevention and treatment of vomiting.
|
|
Managment of constipation.
|
|
Management of gastroenteritis.
|
|
Principles of treatment of Clostridium difficile colitis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Management of type 1 diabetes mellitus. Treatment of gestational diabetes.
|
|
Management of type 2 diabetes.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Post-operative pain management.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Computer room
|
2
|
Topics
|
Colloquium 1: Therapeutic options for cardiovascular diseases, respiratory diseases, gastrointestinal diseases and diabetes.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Pain management.
|
|
Agents for the treatment of glaucoma.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Basic principles of rheumatoid arthritis therapy.
|
|
The basics of treatment of lupus erythematosus.
|
|
Principles of inflammatory bowel disease management.
|
|
Basic principles of psoriasis treatment
|
|
Prevention of transplant rejection.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Principles of therapy for chronic kidney disease.
|
|
Principles of treatment of pyelonephritis and cystitis.
|
|
Treatment options for overactive bladder and urinary incontinence
|
|
Crystalloids.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
High-risk drugs.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Computer room
|
2
|
Topics
|
Colloquium 2: Analgesic therapy. Medicines for glaucoma. Renal disease therapy. Crystalloids. High-risk medicines
|
Bibliography
Required Reading
Hood, P., & Khan, E. Understanding Pharmacology in Nursing Practice, Springer, 2026.Suitable for English stream
Brunton, L. L., & Knollman, B. C. (2022). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (Fourteenth edition.). New York, N.Y: McGraw-Hill Education LLC.Suitable for English stream
Šetlere, Šetlere, Maija, & Rīgas Stradiņa universitāte. (2009). Anestēzijas, intensīvās un neatliekamās aprūpes māsas pamatspecialitāte : mācību materiāls / [galvenā redaktore Maija Šetlere] ; Rīgas Stradiņa universitāte. Rīga: Nacionālais apgāds.
Biksone, Vingre, & Vingre, Ilze. (1998). Klīniskā farmakoloģija un pacienta aprūpe / Gaļina Biksone ; [medicīniskā redaktore Ilze Vingre]. Rīga: [IU “Medbiks”].
Brunton, L. L., & Knollman, B. C. (2022). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (Fourteenth edition.). New York, N.Y: McGraw-Hill Education LLC.Suitable for English stream
Additional Reading
South-Paul, J. E., Matheny, S. C., & Lewis, E. L. (2020). CURRENT Diagnosis & Treatment in Family Medicine, 5th Edition (5th edition.). McGraw-Hill.Suitable for English stream
Ford, S. M., & Roach, S. S. (2010). Roach’s introductory clinical pharmacology / Susan M. Ford, Sally S. Roach. (9th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins.Suitable for English stream
Purviņš, Purviņa, & Purviņa, Santa. (2002). Praktiskā farmakoloģija / Indulis Purviņš, Santa Purviņa. (3., papild. izd.). Rīga: Zāļu infocentrs.