Veidlapa Nr. M-3 (8)
Study Course Description
Laboratory Diagnostics
Course Code
REN_010
Branch of Science
Clinical medicine; Internal medicine
ECTS
4.05
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Vitolds Mackēvičs
Residency Speciality
Speciality
Endocrinologist
Supervisor of Medical Speciality
Vitolds Mackēvičs
Contacts
-
About Study Course
Objective
To provide medical residents with the possibility to acquire theoretical knowledge and practical skills of the methods applied in laboratory diagnostics and experimental research projects. Understanding of making different experiments and execution and interpretation of results according to the standards of molecular biology in order to prepare a physician to read and understand the published experimental and clinical studies purposefully.
Learning Outcomes
Knowledge
1.To understand the clinical and experimental laboratory examinations and the related endocrine pathology theoretically and practically.
Skills
1.To understand the operation principles of the large laboratory analyzers (nephelometry, turbidimetry, etc.). To learn correct interpretation of laboratory test results: clinical blood count, biochemical indicators, indicators of coagulation disorders and thromboses, hormonal indicators, urine tests. To be able to assess different molecular biological examinations related to endocrine pathology. To understand the principles of making these experiments.
Competences
1.To provide a possibility to a medical resident in endocrinology to acquire the knowledge and skills necessary for different laboratory examinations used in research, diagnosis and assessment of endocrine diseases.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
A resident of endocrinology acquires knowledge and skills about various laboratory tests used in the research, diagnosis and evaluation of endocrine diseases. The resident participates in various diagnostic and treatment methods, must attend the planned seminars. Prepare presentations of clinical cases for seminars with an emphasis on laboratory diagnostics. Get acquainted with the latest literature and prepare literature reviews. Understand the peculiarities of laboratory diagnostics and control dynamics of endocrine diseases. Exam test.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
2.
Examination |
-
|
-
|
|
a. a medical resident knows pre-analytical factors of different laboratory parameters,
b. optimal collection of material,
c. test works in seminars and successful settlement,
d. real examination for determination of different measurements at a patient’s bedside.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Methods for determination of protein concentration and activity (biochemistry, spectrometry, immunoblot, ELISA - Enzyme-linked immunosorbent assay) - theory, demonstrations.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Characterization of receptor-ligand interaction in the study of the mechanism of action of drug substances (examples, radioligand binding experiments, tissue sections).
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
In vitro studies: work in sterile conditions with cell cultures, isolated organ systems (heart, aorta) - theory, demonstrations.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
On site
|
Specialized room
|
Topics
|
Experimental laboratory animal models - theory, demonstrations.
a. CNS, toxicology
b. Cardiovascular system
c. Diabetes, metabolic models
|
Total ECTS (Creditpoints):
4.05
Number of Residency Seminars:
4
Length (weeks):
4
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Tutorials in Clinical Chemistry. English edition, by Ibrahim A. Hashim, 2022
2.
Impacts of Medications on Male Fertility (Advances in Experimental Medicine and Biology, Band 1034). English edition, by Erma Z. Drobnis and Ajay K. Nangia, 2019
3.
Clinical Biochemistry: An Illustrated Colour Text. English edition, by Michael J. Murphy MA MD FRCP FRCPath, Rajeev Srivastava MS FRCS FRCPath, et al., 2018
4.
Endocrine Biomarkers: Clinicians and Clinical Chemists in Partnership (Clinical Aspects and Laboratory Determination). English edition, by Hossein Sadrzadeh and Gregory Kline, 2017
5.
Endocrine Pathology: Differential Diagnosis and Molecular Advances. English edition, by Ricardo V. Lloyd, 2016
Additional Reading
1.
Endocrine Pathology: Differential Diagnosis and Molecular Advances. English edition, by Ricardo V. Lloyd, 2010
2.
Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice/ English edition, by Douglas T. Carrell and C. Matthew Peterson, 2010