Clinical Pharmacy
Study Course Implementer
Riga, 21 Consula Street, farmkk@rsu.lv, +371 67061544
About Study Course
Objective
To introduce pharmacy students to the concept of clinical pharmacy, basic principles of pharmacokinetics and their application in clinical practice. To promote understanding of various drug pharmacotherapy options. To analyze the guidelines and actualities of hospital and clinical pharmacy in Latvia and the world.
Preliminary Knowledge
Pharmaceutical and medical chemistry, physiology, pharmacology.
Learning Outcomes
Knowledge
1.After successful acquisition of the course the students will be able to: • describe and explain pharmacokinetic and pharmacodynamic mechanisms; • describe and explain drug absorption, distribution, metabolism and excretion; • describe population needs as regards to medicines, ways of administration, patterns of use and drug effects on the patients; • identify and describe patient-specific data to improve pharmaceutical care.
Skills
1.After successful completion of the course the students will be able to assess and use pharmacokinetic parameters to choose the efficient therapy.
Competences
1.After successfully completing the study course, the student will be able to evaluate the peculiarities of the use of various drugs, will be able to use the acquired knowledge about the diverse pharmacokinetic processes and mechanisms to make competent conclusions about individual pharmacotherapy.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Individual and group work. Analysis of pharmacotherapy situations. Filling in study course evaluation forms. |
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
2.
Examination |
-
|
10 points
|
|
Case studies. |
||
Study Course Theme Plan
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Hospital pharmacy. Clinical pharmacy. The role of the clinical pharmacist in the hospital.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Basic pharmacokinetics. Linear and non-linear pharmacokinetics.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Therapeutic drug monitoring
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Therapeutic drug monitoring
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Alterations in the pharmacokinetics of the medicinal product in different patient groups (geriatric patients, organ failure, pregnant women, etc.)
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Alterations in the pharmacokinetics of the medicinal product in different patient groups (geriatric patients, organ failure, pregnant women, etc.)
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Alterations in the pharmacokinetics of the medicinal product in different patient groups (geriatric patients, organ failure, pregnant women, etc.)
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Alterations in the pharmacokinetics of the medicinal product in different patient groups (geriatric patients, organ failure, pregnant women, etc.)
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Safety and promotion of medicines. Off-label use of medicines
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drug Interaction Analysis
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drug Interaction Analysis
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Drug Interaction Analysis
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drug-induced adverse reactions, their detection, monitoring and action plans
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Drug-induced adverse reactions, their detection, monitoring and action plans
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Drug-induced adverse reactions, their detection, monitoring and action plans
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Polypharmacy and its risks. Prescription cascades
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Polypharmacy and its risks. Prescription cascades
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Polypharmacy and its risks. Prescription cascades
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Study room
|
2
|
Topics
|
Polypharmacy and its risks. Prescription cascades
|
Bibliography
Required Reading
Whittlesea, C., Hodson, K. Clinical Pharmacy and Therapeutics. 6th edition. Elsevier, 2019. RSU: Informācijas centrs
Oxford handbook of clinical pharmacy. Oxford, 2017. RSU: Brīvpieejas abonements; RSU: Informācijas centrs
Additional Reading
Solverman, Richard B. The organic chemistry of drug design and drug action. 2014. RSU: Informācijas centrs
Applied Biopharmaceutics & Pharmacokinetics. Editors Shargel L., Wu-Pong S., Yu A. B. C. 5th edition. McGraw Hill AccessPharmacy, 2022. -892 p.
Applications of Pharmacokinetic Principles in Drug Development. Editor Krishna R. Kluwer Academic Plenum Publishers, 2004. -556 p.
Bauer, L.A. Applied Clinical Pharmacokinetics. McGraw Hill AccessPharmacy, 2014. -759 p.
Drug Benefits and Risks. Editors Boxtel C. J., Santoso B., Edeards I. R. John Wiley & Sons, EBSCOhost Ebook Academic Collection, 2008.
Drug Prescribing in Renal Failure. Editors Aronoff, G. R., Berns, J. S., Brier, M. E., et.al. 4th edition. American College of Physicians, 1999. -176 p.
Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications. 5th edition, 2020.