Biochemistry
Study Course Implementer
Riga, 16 Dzirciema Street, cfbk@rsu.lv, +371 67061550
About Study Course
Objective
Preliminary Knowledge
Learning Outcomes
Knowledge
1.After successful completion of the course the student will be able to: 1. explain the bioenergetic processes in the body – carbohydrates, fat and protein metabolism; 2. illustrate the metabolic regulation options; 3. understand the nutrition and metabolism of the human relationship.
Skills
1.As a result of mastering the study course the student will be able to: 1. to demonstrate the effect of an unbalanced diet on metabolism; 2. to evaluate changes in metabolism in the body; 3. to use the acquired knowledge in the acquisition of clinical disciplines and to integrate it into one's daily work; 4. to use the acquired knowledge about the ingredients of food products and nutrients, their chemical structure, transformations in order to consult on nutrition issues both for larger groups of society and individual individuals; 5. to analyze and argue about the change of substances, the molecular basis of its regulation, the application of biochemistry in nutrition.
Competences
1.The student will be able to apply the acquired knowledge of the chemical processes taking place in the body, their integration and regulation.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Independent theoretical topic of learning through other sources, such as scientific books, publications.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
1. Participation in practical classes, problem solving – pass/fail
2. Writing tests – 50%
3. The final exam – 50%
|
||
Study Course Theme Plan
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Brief description of simple and complex proteins
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Enzymology
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Biochemical functions of the water-soluble vitamins
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Oxy-, oxo- and amino acids
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Carbohydrates and lipids
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Simple proteins. Biuret reaction, the protein precipitation reactions
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Compound proteins. Nucleoprotein hydrolysis product proof in yeast hydrolyzate
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Simple and complex proteins
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Basics of enzyme classification
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Enzyme activity dependence on temperature and pH. Specificity
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Enzyme activity determination (amyloclastic power)
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Enzyme activators and inhibitors
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Enzymes
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Nutrient digestive process
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Carbohydrate, fat and protein digestion process
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
The digestive process
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Carbohydrate metabolism
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Lipid metabolism
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Amino acid metabolism
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Water-soluble vitamins. Vitamin C quantification
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Fat-soluble vitamins
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Vitamins
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Introduction to metabolism. Bioenergetics. Citric acid cycle
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Dietary carbohydrates. Glycogen
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Carbohydrates as an energy source. PVA determination
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Carbohydrate metabolism
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Fat as an energy source
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Ketone formation and determination. Cholesterol
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Lipid metabolism
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Amino acid deamination, AT activity
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Ammonia formation and decontamination. Determination of urea
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Amino acid metabolism
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Introduction to the chemical reactions of the human body
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Enzymology
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Biochemical functions of the water-soluble vitamins
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Carbohydrate metabolism
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Lipid metabolism
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Metabolism, introduction
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Carbohydrates metabolism. Digestion and absorption of carbohydrates
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
3
|
Topics
|
Protein metabolism. Amino acid traffic in the body
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
General properties of enzymes. Nomenclature of enzymes
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Digestion and absorption of carbohydrates, fat, and proteins
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Anatomy of digestive tract, enzymes of digestive tract
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Hydrolytic reactions such as enzymatic hydrolysis of proteins, polysaccharides, fats into small molecules
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Bioenergetic
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Glycolysis – energy generation from carbohydrates (aerobic, anaerobic processes)
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Lactic acid determination
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
3
|
Topics
|
Energy release from fat
|
Bibliography
Required Reading
Николаев, А. Я. Биологическая химия : учебник для медицинских специальностей вузов Москва : Высшая школа, 1989. (akceptējams izdevums)
R.K. Murry, D.K. Granner, D.A.Mayes, U.W. Rodnee. Harper’s illustrated biochemistry: Lange Medical Publications, 2018.
e-studijas (http://estudijas.rsu.lv/).
Additional Reading
PUB MED un citas datu bāzes.
Other Information Sources
R.A. Harvey, D.R. Ferrier. Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews Series), 2010: 544.