Veidlapa Nr. M-3 (8)
Study Course Description
Transfusiology and Immunohematology
Course Code
RHE_001
Branch of Science
Anatomy; Clinical medicine
ECTS
4.95
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Sandra Lejniece
Residency Speciality
Speciality
Hematologist
Supervisor of Medical Speciality
Sandra Lejniece
Contacts
-
About Study Course
Objective
To ensure acquisition and improvement of theoretical knowledge and practical skills in transfusiology and immunohematology according to the requirements of the Regulation of the Haematology specialty in order to prepare a physician for certification in the haematology specialty.
Learning Outcomes
Knowledge
1.A resident will have knowledge of operation principles of blood banks, haemovigilance standards; will have knowledge of the principles of organisation of the donor movement.
Skills
1.After finishing of the study programme a resident will be able to assess indications regarding transfusion of blood preparations, determine indications for application of irradiated blood components and CMV-negative blood components. Will be able to assess indications when it is necessary to determine blood compatibility in the special immunohaematology laboratory.
Competences
1.To understand donor selection principles, contraindications; To participate in donor selection, examine donors; To participate in thrombocyte apheresis procedures, observe a donor during the procedure; To acquaint oneself with immunohaematology laboratory; To acquaint oneself with HLA-typing laboratory.
Assessment
Individual work
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Title
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% from total grade
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Grade
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1.
Individual work |
-
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-
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To learn donor selection principles, contraindications;
To participate in donor selection, examine at least 12 donors;
To participate in at least 5 thrombocyte apheresis procedures, observe a donor during the procedure;
To acquaint oneself with immunohaematology laboratory;
To acquaint oneself with HLA-typing laboratory.
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Examination
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Examination |
-
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-
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Study Course Theme Plan
FULL-TIME
Part 1
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Seminar
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Modality
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Location
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On site
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Auditorium
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Topics
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Regulatory enactments of the European Union and Latvia governing transfusions. Donor selection principles, donor observation and potential complications. Preparation, safety and storage of standard and special blood components (blood, erythrocyte mass, thrombocyte mass, plasma, cryoprecipitate, irradiated washed and pathogen- reduced components).
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Seminar
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Modality
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Location
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|---|---|---|
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On site
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Auditorium
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Topics
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Immunohaematology problems: compatibility standards, direct and indirect Coombs test, ABO and Resus factor types in red cells. Small antigens and antibodies of red cells.
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Seminar
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Modality
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Location
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|---|---|---|
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On site
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Auditorium
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Topics
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Recommendations and regulations governing blood and blood component transfusion. Indications for transfusion of erythrocyte mass, thrombocyte mass, plasma, intravenous immunoglobulins. Alternate procedures for allogeneic blood Recommendations and regulations governing blood and blood component transfusion. Indications for transfusion of erythrocyte mass, thrombocyte mass, plasma, intravenous immunoglobulins. Alternate procedures for allogeneic blood transfusion. Massive transfusions (in surgery,
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Total ECTS (Creditpoints):
4.95
Number of Residency Seminars:
3
Length (weeks):
4
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Guide to the preparation, use and quality assurance of blood components. 20th ed. Council of Europe, 2020.
2.
Robert W. Maitta Clinical Principles of Transfusion Medicines, Elsevier 2018.
3.
Michael F. Murphy, David J. Roberts and MarkH. Yazer Practical Transfusion medicine. 5th ed. Wiley Blackwell 2017.
4.
Denise M. Harmening Modern blood banking&Transfusion Practices, 7th ed. F. A. Davis Company, 2018.
5.
Liepiņš M., Lejnieks A. Rekomendācijas empīriskai un etiotropai antimikrobiālai ārstēšanai. 4. redakcija. Aslimnīca, 2020.
6.
Lejniece S. Klīniskā hematoloģija. Rīga: SIA medicīnas apgāds, 2020.
7.
The EBMT Handbook. Hematopoietic Stem Cell Transplantation and Cellular Therapies. 7th edition. Ed. by Carreras E., Dufour C., Mohty M., Kroger N. Springer International Publishing, 2019.
8.
John P. Greer MD, Daniel A. Arber MD, Bertil E. Glader MD, et al. Wintrobe’s Clinical Hematology. 14th edition. Lippincott, William & Wilkins, 2018.
9.
Abbas A. K., Lichtman A. H., Shiv P. Basic Immunology: Functions and Disorders of the Immune System. 6th edition. Elsevier, 2019.
10.
Male D., Brostoff J., Roth D. B., Roitt I. Immunology. 8th edition. Saunders, 2012.
11.
Turgeon M. L. Immunology and serology in Laboratory Medicine. 6th edition. Elsevier, 2017.
Additional Reading
1.
Daniels G., Bromilow I. Essential Guide to Blood Groups. Oxford: Blackwell; 2009.
2.
Ņemceva G., Sisene I., Šteinerte A. Praktiskā transfuzioloģija. Rīga: Medicīnas apgāds; 2009.
3.
Quinley E. D., Immunohematology. Principles & Practice. 3rd ed.- Lippincot Williams&Wilkins, 2011.
Other Information Sources
1.
27.02.2018. MK noteikumu Nr. 1037 „Noteikumi par cilvēka asiņu un asins komponentu savākšanas, testēšanas, apstrādes, uzglabāšanas un izplatīšanas kvalitātes un drošības standartiem un kompensāciju par izdevumiem zaudētā asins apjoma atjaunošanai”
2.
LVS EN ISO/IEC 17025:2017 “Testēšanas un kalibrēšanas laboratoriju kompetences vispārīgās prasības”
3.
LVS EN ISO 15189:2013 “Medicīnas laboratorijas. Kvalitātes un kompetences prasības”
4.
Eiropas Parlamenta un Padomes Direktīvu 2002/98/EK (2003.gada 27. janvāris), ar kuru nosaka kvalitātes un drošības standartus attiecībā uz cilvēka asins un asins komponentu savākšanu, testēšanu, apstrādi, uzglabāšanu un izplatīšanu, kā arī groza Direktīvu 2001/83/EK
5.
Komisijas Direktīvas 2016/62/EK (2016. gada 25. jūlijs) par Eiropas Parlamenta un Padomes Direktīvas 2005/62/EK piemērošanu attiecībā uz Kopienas standartiem un specifikācijām, kas attiecas uz asins sagatavotāju kvalitātes sistēmu
6.
Komisijas Direktīvas 2005/61/EK (2005. gada 30. septembris), ar ko īsteno Eiropas Parlamenta un Padomes Direktīvu 2002/98/EK attiecībā uz izsekojamības prasībām un nopietnu blakņu un nevēlamu notikumu paziņošanu
7.
Komisijas Direktīvas 2003/94/EK (2003. gada 8. oktobris), ar ko nosaka labas ražošanas prakses principus un pamatnostādnes attiecībā uz cilvēkiem paredzētām zālēm un pētāmām cilvēkiem paredzētām zālēm
8.
Komisijas Direktīva 2004/33/EK (2004. gada 22. marts) par Eiropas Parlamenta un Padomes Direktīvas 2002/98/EK piemērošanu attiecībā uz dažām tehniskajām prasībām asinīm un asins komponentiem