Biology and Genetics
Study Course Implementer
Riga, 16 Dzirciema Street, bmk@rsu.lv, +371 67061584
About Study Course
Objective
Preliminary Knowledge
Learning Outcomes
Knowledge
1.Upon completion of the course, students will have acquired basic knowledge of cellular and genetic processes in the human and genesis of pathologies.
Skills
1.Upon completion of the course, students will learn the skill to analyze microphotograph images of cells and describe observations and will be able to solve simple tasks in genetics.
Competences
1.Upon completion of the course, students will be able to analyse cases in medical genetics. They will evaluate the role of organoids in functioning of tissues, organs and the body.
Assessment
Individual work
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Individual work |
-
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-
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On the basis of certain pre-defined criteria, individual work on "My family tree" should be prepared and presented in the lesson. Using knowledge on chromosomal diseases, students should be able to analyse the case reports of a chromosomal disease and present their observations in the lesson.
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Examination
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Examination |
-
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-
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After every two lectures, students must complete an e-test on the topics covered. The test must be completed within a certain time and will be assessed with a mark. Also the practical class protocols will be evaluated. A total of 8 evaluations in the course. If an e-test or e-protocol is not submitted within the deadline, it is evaluated as fail. The course final grade will be formed from average mark of the e-tests and e-protocols. If the student has not completed/ participated in 25% of the course activities (tests and protocols), then the exam evaluation criteria described above are no longer valid and the oral exam must be taken.
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Study Course Theme Plan
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
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2
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Topics
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The subject of the human biology. Life, the diversity of its forms. Prokaryotes. Eukaryotes.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Eukaryotic cell. Plasma membrane; structure, functions, pathology.
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-
Lecture
|
Modality
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Location
|
Contact hours
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|---|---|---|
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Off site
|
E-Studies platform
|
2
|
Topics
|
Eukaryotic cell cytoplasm; structure, functions, pathology.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
|
E-Studies platform
|
2
|
Topics
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The nucleus of a cell. Chromatin, its types. The chromosomes. Human karyotype.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
|
E-Studies platform
|
2
|
Topics
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Basis of molecular biology. Structure of DNA. Replication. Gene expression. Transcription. Translation.
|
-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
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Cell cycle. Types of cell division. Mitosis. Meiosis. Atypical cell division. Cell division defects and human pathology.
|
-
Lecture
|
Modality
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Location
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Contact hours
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|---|---|---|
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Off site
|
E-Studies platform
|
2
|
Topics
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Gametogenesis. Oogenesis. Spermatogenesis. Gamete anomalies. Biological basis of fertilisation.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
|
E-Studies platform
|
2
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Topics
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Genetics. Mendel’s laws. Mono-, di, polyhybrid cross. Test-cross.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Gene interaction. Types of interactions between allelic and non-allelic genes. Gene linkage. Chromosomal theory of heredity.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Types of inheritance. Autosomal; X and Y chromosome-linked and multifactorial types of inheritance.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Variability, its types. Alterations on genes, chromosomes, genomes.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Chromosomal disorders.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Cell structure and cell types (microscopic slides). Implementation of the protocol.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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Off site
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E-Studies platform
|
2
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Topics
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Mitosis in animal and plant cells (analysis of microscopic slides and schemes). Gametogenesis; germ cell morphology (analysis of microscopic slides and schemes).
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
|
Off site
|
E-Studies platform
|
2
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Topics
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Solving genetic problems.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
|
Off site
|
E-Studies platform
|
2
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Topics
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Family tree construction and analysis. Case study of chromosomal diseases.
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Bibliography
Required Reading
Lekciju materiāls (e-studijās)
A. Krūmiņa, V. Baumanis. - Eikariotu šūnu bioloģija, RSU, Rīga, 2015
Turnpenny P.D., & Ellard S., Emery's Elements of Medical Genetics, 15th edition, Elsevier, 2017
Additional Reading
Balodis V Ģ u.c., Rokasgrāmata bioloģijā, Zvaigzne ABC, 2015
Other Information Sources
National Center for Biotechnology Information Search database. Available from: www.ncbi.nlm.nih.gov
The New England Journal of Medicine (NEJM)
S. Madera. - Bioloģija. I, II un III daļa, R, Zvaigzne ABC, 2001