Veidlapa Nr. M-3 (8)
Study Course Description

Cytology and Diagnostics of Oncological Diseases

Main Study Course Information

Course Code
RLA_012
Branch of Science
Clinical medicine; Pathology
ECTS
6.90
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To prepare laboratory doctors capable of performing cytological examination of different biological materials. To use cytological examination for diagnostics and differential diagnostics of oncological diseases, to interpret tumour marker indicators. To use examination algorithms based on international guidelines and recommendations, to interpret the obtained results. To master internal and external quality control methods in cytology and laboratory diagnostics of oncological diseases.

Learning Outcomes

Knowledge

1.- to describe principles of cytological testing; - to characterise foundations of cytological diagnostics of different diseases; - to evaluate advantages of different groups of diagnostic methods; - to evaluate the use and significance of cytological examination in prevention and early diagnostics; - to characterise criteria of cytological changes.

Skills

1.- to prepare samples for cytological examination; - to evaluate signs of inflammation; - to perform cytological examination in prevention and early diagnostics of female gynaecological diseases; - to perform diagnostics of cervical precancer and cancer; - to perform cytological diagnostics of mammary gland diseases; - to perform cytological diagnostics of urinary tract and urinary bladder diseases; - to evaluate morphological changes in exudate and transudate sediments.

Competences

1.To perform a cytological examination of human biological material. Based on exercise results to perform diagnostics, differential diagnostics of oncological diseases and to interpret results. To use cytological diagnostics criteria and examination algorithms for diagnostics of diseases and to recommend further examination activity to clinicians.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Preparation of a presentation about the application of latest methods in laboratory diagnostics of oncological diseases. In-depth research: problems of evaluation and interpretation of cytological examination results.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
2.

Examination

-
-
Assessment of knowledge – written answers to questions at the end of the study course.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Application and role of cytological examination in the prevention and early diagnosis of gynecological diseases in women. Bethesda classification of cytological pathology of the cervix.
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Cytological examination of morphological material taken from the breast. Diagnosis of benign, pre-cancerous diseases and malignant processes of the breast.
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Paris cytological classification of urinary and bladder diseases, morphological changes of urothelial cells. Cytological examination of skin, mucous membranes, scratches
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Classification of benign and malignant tumors of the respiratory organs, possibilities of cytological examination. Cytological examination of puncture material of serous cavities.
  1. Seminar

Modality
Location
On site
Auditorium

Topics

Bethesda cytological classification of thyroid diseases, TIRADS (Thyroid Imaging Reporting and Data System) thyroid malignancy risk classification, cytological diagnostic possibilities.
Total ECTS (Creditpoints):
6.90
Number of Residency Seminars:
5
Length (weeks):
6
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Edit Titmuss, Cliffe Adams. Cervical Cytology: Conventional and Liquid-based. 1st Edition. ISBN-13: 978-1853156540

2.

Cytology. Diagnostic Principles and Clinical Correlates. 4th Edition.

3.

Clinical Microbiology Procedures Handbook. Published by American Society for Microbiology. United States, 2016

4.

Marluce Bibbo, David Wilbur. Comprehensive Cytopathology. 4th Edition

5.

Diagnostic Cytopathology Essentials. 1st Edition. Ed: Gabrijela Kocjan, Winifred Gray, et.al.

6.

Cytology E-Book: Diagnostic Principles and Clinical Correlates. Ed: Edmund S. Cibas, Barbara S. Ducatman, 2014

Additional Reading

1.

Practical Cytopathology. Huihong XuXiaohua QianHe Wang. 2020

2.

Grace McKee. Atlas of Non-gynecological Cytology.

3.

The Bethesda System for Reporting Cervical Cytology. Definitions, Criteria, and Explanatory Notes. 3rd Edition. Edited by R. Nayar, D. Wilbur. 2015, pp 321.Springer International Publishing, Cham, Switzerland.

4.

A comparative study of conventional and liquid-based cervical cytology. Ed: Mehmet Şükrü Budak, Mehmet B. Senturk, Cihan Kaya, et.al. DOI: 10.17772/gp/60980·Pubmed: 27306127·Ginekol Pol 2016;87(3):190-193.

5.

Diagnostic Cytopathology Essentials. 1st Edition, Ed: Gabrijela Kocjan, Winifred Gray, et.al.

Other Information Sources

1.

Journal of Cytology

2.

Cytopathology. Editor-in-Chief: Professor Minaxi Desai

3.

Journal of Cytology & Histology

4.

Journal Acta Cytologica

5.

E. Hussaina Lipi. Liquid based-cytology. Pap smear dataset for automated multi-class diagnosis of pre-cancerous and cervical cancer lesions. ScienceDirect, June 2020, 105589

6.

Journal of Cytology & Molecular Biology (JCMB)

7.

Molecular Biology of the Cell (MBoC)