Care of Elderly Haematological Patients
Study Course Implementer
Residency Speciality
-
About Study Course
Objective
Learning Outcomes
Knowledge
1.- Will know about changes in normal haematological processes as the body ages; - Will know about options for assessing comorbidities, their impact on therapy; - Will know about geriatric oncology; - Will know about the impact of age on the pharmacodynamics and pharmacokinetics of medicines; - Will know about palliative care of patients.
Skills
1.- Will be able to prescribe treatment for geriatric patients; - Will be able to cooperate with the patient’s family members.
Competences
1.Prescribing treatment for geriatric patients. Multidisciplinary approach to treating patients.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
1. Independently studies the literature related to the course topics;
2. Independently prepares for seminars;
3. Independently collects disease anamnesis data, objectively examines the patient, formulates a preliminary diagnosis, which is discussed with the lecturer;
4. Gets acquainted with and analyses medical documentation;
5. Completes medical documentation;
6. Independently follows the instructions of the certified specialist.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Mandatory attendance of seminars (100%) and performance of practical work (100%) in each study course.
|
||
Study Course Theme Plan
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Changes in normal haematological processes as the body ages. Options for assessing comorbidities, their impact on therapy. Geriatric oncology.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Impact of age on the pharmacodynamics and pharmacokinetics of medicines.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Palliative care of patients. End-of-life decisions. Cooperation of the multidisciplinary team with the patient and their family.
|
Bibliography
Required Reading
Alvis BD, Hughes CG. Physiology Considerations in Geriatric Patients. Anesthesiol Clin. 2015 Sep;33(3):447-56. doi: 10.1016/j.anclin.2015.05.003. Epub 2015 Jul 3. PMID: 26315630; PMCID: PMC4556136.
Bruno B, De Ramon Ortiz C, Ligozat S, Samii K, Chevalley T. Le myélome multiple chez la personne âgée: impact d’une évaluation gériatrique [Multiple myeloma in the elderly: impact of a geriatric assessment]. Rev Med Suisse. 2019 Nov 6;15(670):2032-2038. French. PMID: 31696678.
Emile JF, Abla O, Fraitag S, et al. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood 2016; 127:2672
S.Lejniece. Klīniskā hematoloģija. Medicīnas Apgāds, 2020.
Klīnisko analīžu rokasgrāmata. E.Gulbja laboratorija. Izdevējs E.Gulbja laboratorija, 2019.
Alla Rivkina. Plūsmas citometrijas metode hematoloģisko slimību diagnostikā. SIA Medicīnas apgāds, 2019
Other Information Sources
González-Montalvo JI, Ramírez-Martín R, Menéndez Colino R, Alarcón T, Tarazona-Santabalbina FJ, Martínez-Velilla N, Vidán MT, Pi-Figueras Valls M, Formiga F, Rodríguez Couso M, Hormigo Sánchez AI, Vilches-Moraga A, Rodríguez-Pascual C, Gutiérrez Rodríguez J, Gómez-Pavón J, Sáez López P, Bermejo Boixareu C, Serra Rexach JA, Martínez Peromingo J, Sánchez Castellano C, González Guerrero JL, Martín-Sánchez FJ. Geriatría transversal. Un reto asistencial para el siglo xxi [Cross-speciality geriatri
Owusu C, Berger NA. Geriatric management of older cancer patients: A call for action beyond assessments. J Geriatr Oncol. 2019 Nov;10(6):845-846. doi: 10.1016/j.jgo.2019.08.007. Epub 2019 Aug 29. PMID: 31474472.
Sekeres MA, Guyatt G, Abel G, Alibhai S, Altman JK, Buckstein R, Choe H, Desai P, Erba H, Hourigan CS, LeBlanc TW, Litzow M, MacEachern J, Michaelis LC, Mukherjee S, O'Dwyer K, Rosko A, Stone R, Agarwal A, Colunga-Lozano LE, Chang Y, Hao Q, Brignardello-Petersen R. American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults. Blood Adv. 2020 Aug 11;4(15):3528-3549. doi: 10.1182/bloodadvances.2020001920. PMID: 32761235; PMCID: PMC7422124.
Soubeyran P, Bellera C, Goyard J, Heitz D, Curé H, Rousselot H, Albrand G, Servent V, Jean OS, van Praagh I, Kurtz JE, Périn S, Verhaeghe JL, Terret C, Desauw C, Girre V, Mertens C, Mathoulin-Pélissier S, Rainfray M. Screening for vulnerability in older cancer patients: the ONCODAGE Prospective Multicenter Cohort Study. PLoS One. 2014 Dec 11;9(12):e115060. doi: 10.1371/journal.pone.0115060. PMID: 25503576; PMCID: PMC4263738.
Battisti NML, Mislang AR, Cooper L, O'Donovan A, Audisio RA, Cheung KL, Sarrió RG, Stauder R, Soto-Perez-de-Celis E, Jaklitsch M, Williams GR, O'Hanlon S, Alam M, Cairo C, Colloca G, Gil LA Jr, Sattar S, Kantilal K, Russo C, Lichtman SM, Brain E, Kanesvaran R, Wildiers H. Adapting care for older cancer patients during the COVID-19 pandemic: Recommendations from the International Society of Geriatric Oncology (SIOG) COVID-19 Working Group. J Geriatr Oncol. 2020 Nov;11(8):1190-1198. doi: 10.101
Scotté F, Bossi P, Carola E, Cudennec T, Dielenseger P, Gomes F, Knox S, Strasser F. Addressing the quality of life needs of older patients with cancer: a SIOG consensus paper and practical guide. Ann Oncol. 2018 Aug 1;29(8):1718-1726. doi: 10.1093/annonc/mdy228. PMID: 30010772.
Zweegman S, Engelhardt M, Larocca A; EHA SWG on ‘Aging and Hematology’. Elderly patients with multiple myeloma: towards a frailty approach? Curr Opin Oncol. 2017 Sep;29(5):315-321. doi: 10.1097/CCO.0000000000000395. PMID: 28763310.
Abel GA, Klepin HD. Frailty and the management of hematologic malignancies. Blood. 2018 Feb 1;131(5):515-524. doi: 10.1182/blood-2017-09-746420. Epub 2017 Nov 15. PMID: 29141942.
Rowswell-Turner RB, Barr PM. Treatment of chronic lymphocytic leukemia in older adults. J Geriatr Oncol. 2017 Sep;8(5):315-319. doi: 10.1016/j.jgo.2017.04.004. Epub 2017 May 6. PMID: 28487078.
Molica S, Giannarelli D, Levato L, Mirabelli R, Levato D, Lentini M, Piro E. A simple score based on geriatric assessment predicts survival in elderly newly diagnosed chronic lymphocytic leukemia patients. Leuk Lymphoma. 2019 Mar;60(3):845-847. doi: 10.1080/10428194.2018.1508674. Epub 2018 Oct 2. PMID: 30277125.
Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 2016; 127:2391-2405. https://doi.org/10.1182/blood-2016-03-643544
Loh KP, Christofyllakis K, Huang LW, Mims A. Geriatric Hematology Research presented at the 2018 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology Perspective Paper. J Geriatr Oncol. 2019 Mar;10(2):186-191. doi: 10.1016/j.jgo.2019.01.006. Epub 2019 Jan 18. PMID: 30661875; PMCID: PMC6409131.
Eid A, Hughes C, Karuturi M, Reyes C, Yorio J, Holmes H. An interprofessionally developed geriatric oncology curriculum for hematology-oncology fellows. J Geriatr Oncol. 2015 Mar;6(2):165-73. doi: 10.1016/j.jgo.2014.11.003. Epub 2014 Dec 6. PMID: 25487037; PMCID: PMC4743749.
Goede V, Stauder R. Multidisciplinary care in the hematology clinic: Implementation of geriatric oncology. J Geriatr Oncol. 2019 May;10(3):497-503. doi: 10.1016/j.jgo.2018.09.003. Epub 2018 Sep 18. PMID: 30241779.