Veidlapa Nr. M-3 (8)
Study Course Description
Clinical Pharmacy
Course Code
LFK_013
Branch of Science
Basic medicine; Clinical Pharmacy
ECTS
3.00
Target Audience
Pharmacy
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Dace Bandere
Structure Unit Manager
Baiba Mauriņa
Structural Unit
Department of Applied Pharmacy
Contacts
Riga, 21 Consula Street, farmkk@rsu.lv, +371 67061544
About Study Course
Objective
To introduce pharmacy students to the concept of clinical pharmacy, basic principles of pharmacokinetics and their application in clinical practice. To promote understanding of various drug pharmacotherapy options. To analyze the guidelines and actualities of hospital and clinical pharmacy in Latvia and the world.
Preliminary Knowledge
Pharmaceutical and medical chemistry, physiology, pharmacology.
Learning Outcomes
Knowledge
1.After successful acquisition of the course the students will be able to: • describe and explain pharmacokinetic and pharmacodynamic mechanisms; • describe and explain drug absorption, distribution, metabolism and excretion; • describe population needs as regards to medicines, ways of administration, patterns of use and drug effects on the patients; • identify and describe patient-specific data to improve pharmaceutical care.
Skills
1.After successful completion of the course the students will be able to assess and use pharmacokinetic parameters to choose the efficient therapy.
Competences
1.After successfully completing the study course, the student will be able to evaluate the peculiarities of the use of various drugs, will be able to use the acquired knowledge about the diverse pharmacokinetic processes and mechanisms to make competent conclusions about individual pharmacotherapy.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Individual and team work. Presentation of a report on pharmacokinetic processes. Analysis of pharmacotherapy situations and case situations.
Completion of study course evaluation questionnaires.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
2.
Examination |
-
|
-
|
|
Case study analysis. Individual work – analysis of pharmacotherapy situations. Literature data analysis 50% and situation analysis 50%
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Hospital pharmacy. Clinical pharmacy. Clinical pharmacokinetics and pharmacodynamics.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Hospital pharmacy. Clinical pharmacy. Clinical pharmacokinetics and pharmacodynamics.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drug absorption, distribution, metabolism, elimination.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drug absorption, distribution, metabolism, elimination.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Linear and non-linear pharmacokinetics. Drug interactions and side effects. Drug metabolism.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Linear and non-linear pharmacokinetics. Drug interactions and side effects. Drug metabolism.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drugs for pediatric and geriatric population. Drugs and kidney failure.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Drugs for pediatric and geriatric population. Drugs and kidney failure.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Pharmacokinetics of antibiotics. Individual drug therapy.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Pharmacokinetics of antibiotics. Individual drug therapy.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Cardiological drugs – Digoxin, Lidocaine, Procainamide, Quinidine. Case study. Pharmacotherapy for chronic diseases and monitoring methods for safe and effective therapy.
Personalised medicine from the perspective of a clinical pharmacist.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Cardiological drugs – Digoxin, Lidocaine, Procainamide, Quinidine. Case study. Pharmacotherapy for chronic diseases and monitoring methods for safe and effective therapy.
Personalised medicine from the perspective of a clinical pharmacist.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Individual therapy. Antiepileptics – Phenytoin, Carbamazepine, Valproates, Phenobarbital, Ethosuximide. Theophylline, Lithium, Ciclosporin, Tacrolimus. Dosage calculations.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Individual therapy. Antiepileptics – Phenytoin, Carbamazepine, Valproates, Phenobarbital, Ethosuximide. Theophylline, Lithium, Ciclosporin, Tacrolimus. Dosage calculations.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
The role of the clinical pharmacist in the hospital.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
The role of the clinical pharmacist in the hospital.
|
Total ECTS (Creditpoints):
3.00
Contact hours:
32 Academic Hours
Final Examination:
Exam (Oral)
Bibliography
Required Reading
1.
Whittlesea, C., Hodson, K. Clinical Pharmacy and Therapeutics. 6th edition. Elsevier, 2019. RSU:Informācijas centrs
2.
Oxford handbook of clinical pharmacy. Oxford, 2017. RSU:Brīvpieejas abonements RSU:Informācijas centrs
Additional Reading
1.
Solverman, Richard B. The organic chemistry of drug design and drug action. 2014. RSU:Informācijas centrs
2.
Applied Biopharmaceutics & Pharmacokinetics. Editors Shargel L., Wu-Pong S., Yu A. B. C. 5th edition. McGraw Hill AccessPharmacy, 2022. -892 p.
3.
Applications of Pharmacokinetic Principles in Drug Development. Editor Krishna R. Kluwer Academic Plenum Publishers, 2004. -556 p.
4.
Bauer, L.A. Applied Clinical Pharmacokinetics. McGraw Hill AccessPharmacy, 2014. -759 p.
5.
Drug Benefits and Risks. Editors Boxtel C. J., Santoso B., Edeards I. R. John Wiley & Sons, EBSCOhost Ebook Academic Collection, 2008.
6.
Drug Prescribing in Renal Failure. Editors Aronoff, G. R., Berns, J. S., Brier, M. E., et.al. 4th edition. American College of Physicians, 1999. -176 p.
7.
Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications. 5th edition, 2020.