Veidlapa Nr. M-3 (8)

Study Course Description

Embryology

Main Study Course Information

Course Code

MK_074

Branch of Science

Clinical medicine; Histology and Cytology

ECTS

3.00

Target Audience

Dentistry

LQF

Level 7

Study Type And Form

Full-Time

Study Course Implementer

Course Supervisor

Māra Pilmane

Structure Unit Manager

Māra Pilmane

Structural Unit

Department of Morphology

Contacts

Riga, 9 Kronvalda boulevard, aaiak@rsu.lv, +371 67061551

About Study Course

Objective

Students develop understanding of the development of embryology; basic human development (fertilization, implantation, bi- and trilaminar embryo, placentation, development of three germ layers); of the main cellular, subcellular and molecular processes (induction, determination, differentiation and growth), and of processes at all stages of embryogenesis and fetogenesis. Students develop understanding of histogenesis and organogenesis of particular tissues and organs. Students acquire knowledge of critical periods, critical factors and different congenital and developmental anomalies that arise at different periods of intrauterine life. Students acquire knowledge of achievements in modern experimental embryology and their practical use in daily work of a doctor, and of the elements and significance of comparative embryology.

Preliminary Knowledge

Biology, histology, anatomy and genetics.

Learning Outcomes

Knowledge

1.On successful completion of the study course students will be able to demonstrate understanding of embryology and significance of prenatal diagnostic methods, to describe structural features of primordia in tissue and organs at different developmental stages, to define risk periods in histo- and organogenesis, and to analyse the most often observed developmental anomalies.

Skills

1.The student will be able to determine the abnormalities of the human system and organs under a microscope, but will recognize the developmental stages of the face, jaw and neck, as well as the sensory organs, analyze their correspondence to the time of development and standard embryonic structures. Will be able to assess possible teratogenic effects. Will be able to describe embryological schemes. Will be able to interpret and analyze course databases and cited literature sources.

Competences

1.Students will be able to recognize embryonic tissue and organ morphology and structure in clinical specimens. They can analyse variations at different stages of embryonic development and distinguish between healthy and pathological tissues in specimens. The students will be able to estimate the significance of various inducers on the developmental processes with respect to postnatal life.

Assessment

Individual work

Title	% from total grade	Grade
1. Individual work	-	-
As part of the study course, individual work is organized by analyzing micropreparations and preparing lesson protocols. Individual work with recommended literature, according to the topic of lectures and classes. Analysis of the results of scientific publications, for deepening the understanding of the study course. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.

Examination

Title	% from total grade	Grade
1. Examination	-	-
• Laboratory class protocols of appropriate quality finished and submitted in due time; • Multiple choice examination in combination with practical analysis of specimens at the end of the course. 10 lectures; 6 classes; Semester pass after handing in appropriately prepared protocols and attended practical classes and lectures; final written exam with multiple choice questions and 5 slide recognition (50/50). During the examination, the students’ theoretical knowledge of embryonic tissue and organ morphology and practical skills in analyzing specimens are tested. Students show how to specify age-related changes in tissues and organs. They demonstrate their understanding of the development of tissues and organs as well as the ability to relate morphology with processes.

Study Course Theme Plan

FULL-TIME

Part 1

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Teratology. Main terms. Historical aspects of embryology content and tasks. Experimental embryology. Periods of intrauterine life.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Spermatogenesis. Ovogenesis. Germ cells. Conception. Embarrassment. Implantation.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Development of bilateral embryo. Development of extraembryonic structures. Gastrulation and neurulation. Development of trilaminar embryo. Embryonal folding. Placenta. Foetal membranes. Umbilical cord.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Formation of external forms of the body. Development of the axis skeleton, limbs. Muscle development.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the cardiovascular system. Development of the lymphatic system.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the urogenital system. Development of skin, its derivatives, endocrine system.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the face and neck. Development of oral cavity, tongue.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the digestive and respiratory system.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

CNS and PNS development. Eye and ear development.

Lecture

Modality	Location	Contact hours
On site	Other	2

Topics

Stem cells.

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Periods of embryogenesis. Germ cells. Spermatogenesis, oogenesis. 1st week of embryogenesis. 2nd and 3rd week of embryogenesis. Placentation.

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the axis skeleton, limbs, muscle tissue. Development of the heart, lymphatic system, urogenital system. Development of the skin, endocrine system.

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Colloquium: 1.-6. topic. Preparations for lessons 1. and 2.

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Development of the face, oral cavity and tongue. Development of the digestive, respiratory and nervous systems.

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Development of sensory organs. Development of the total organism

Class/Seminar

Modality	Location	Contact hours
On site	Other	2

Topics

Colloquium: 7.-11. topics. Preparations for lessons 4., 5. Test.

Total ECTS (Creditpoints):

3.00

Contact hours:

32 Academic Hours

Final Examination:

Exam (Written)

Bibliography

Required Reading

Pilmane M., Pļaviņa L., Kavak V. 2016. Embryology and Anatomy for Health Sciences. Rīgas Stradiņa universitāte. 511 lpp. ISBN-10: 9984793915, ISBN-13: 978-9984793917

Pilmane M., Šūmahers G.-H. 2006. Medicīniskā embrioloģija. Rīgas Stradiņa universitāte. 335 lpp. ISBN10: 9984788024, ISBN13: 9789984788029. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji.

Sadler T.W. 2018. Langman's Medical Embryology. 14th Edition. LWW. 456 p. ISBN-10:1496383907, ISBN-13:978-1496383907

Schoenwolf Gary C., Bleyl Steven B., Brauer Philip R., Francis-West Philippa H. 2021. Larsen's Human Embryology. 6th Edition. Churchill Livingstone. 560 p. ISBN-10:032369604X, ISBN-13:978-0323696043

Moore Keith L., Persaud T. V. N., Torchia Mark G. 2015. The Developing Human: Clinically Oriented Embryology. 10th Edition. Saunders. 560 p. ISBN-10: 0323313388, ISBN-13: 978-0323313384

Moore Keith L., Persaud T. V. N., Torchia Mark G. 2019. Before We Are Born: Essentials of Embryology and Birth Defects. 10th Edition. Saunders. 350 p. ISBN-10:0323608493, ISBN-13:978-0323608497

Carlson Bruce M. 2019. Human Embryology and Developmental Biology. 6th Edition. Saunders. 496 p. ISBN-10:0323523757, ISBN-13:978-0323523752

Dudek Dr. Ronald W. 2013. High-Yield Embryology. 5th Edition. LWW. 176 p. ISBN-10: 1451176104, ISBN-13: 978-1451176100

Slack Jonathan M. W. 2018. The Science of Stem Cells. 1st Edition. Wiley-Blackwell. 264 p. ISBN-10: 1119235154, ISBN-13: 978-1119235156

10.

Ārvalstu studentiem/For international students

11.

Slack Jonathan M. W. 2018. The Science of Stem Cells. 1st Edition. Wiley-Blackwell. 264 p. ISBN-10: 1119235154, ISBN-13: 978-1119235156

12.

Dudek Dr. Ronald W. 2013. High-Yield Embryology. 5th Edition. LWW. 176 p. ISBN-10: 1451176104, ISBN-13: 978-1451176100

13.

Carlson Bruce M. 2019. Human Embryology and Developmental Biology. 6th Edition. Saunders. 496 p. ISBN-10:0323523757, ISBN-13:978-0323523752

14.

Moore Keith L., Persaud T. V. N., Torchia Mark G. 2019. Before We Are Born: Essentials of Embryology and Birth Defects. 10th Edition. Saunders. 350 p. ISBN-10:0323608493, ISBN-13:978-0323608497

Additional Reading

Fehrenbach M., Popowics T. 2016. Illustrated Dental Embryology, Histology, and Anatomy. 4th Edition. Elsevier. 352 p. ISBN: 9780323675536

Blechschmidt E. 2004. The Ontogenetic Basis of Human Anatomy: A Biodynamic Approach to Development from Conception to Birth. 1st Edition. North Atlantic Books. 272 p. ISBN-10: 155643507X, ISBN-13: 978-1556435072. Precīzs embrioloģisko struktūru attainojums, nav atkārtota izdevuma.

Blechschmidt E., Gasser R.F. 2012. Biokinetics and Biodynamics of Human Differentiation: Principles and Applications. Reprint Edition. North Atlantic Books. 312 p. ISBN-10: 1583944524, ISBN-13: 978-1583944523

Breedlove Marc S. 2017. Foundations of Neural Development. 1st Edition. Sinauer Associates is an imprint of Oxford University Press. 370 p. ISBN-10: 1605355798

Cochard Larry R. 2012. Netter's Atlas of Human Embryology: Updated Edition. 1st Edition. Saunders. 288 p. ISBN-10: 1455739774, ISBN-13: 978-1455739776

Dudek Dr. Ronald W. 2008. BRS Embryology. 6th Edition. LWW. 336 p. ISBN-10: 1451190387, ISBN-13: 978-1451190380

England Marjorie A. 1983. Colour Atlas of Life Before Birth: Normal Fetal Development. Year Book Medical Pub. 224 p. ISBN-10: 0815131194, ISBN-13: 978-0815131199. Viena no retajām grāmatām, kur publicēti embriju 2D attēli un to histoloģiskās struktūras. Precīzs un korekts embrioloģisko struktūru attainojums un grāmatai nav atkārtota izdevuma.

Hombría Castelli-Gair J., Bovolenta P. 2016. Organogenetic Gene Networks: Genetic Control of Organ Formation. 1st Edition. Springer. 376 p. ISBN-10: 3319427652, ISBN-13: 978-3319427652

Lambert Wayne H., Wineski Lawrence E. 2010. Lippincott's Illustrated Q&A Review of Anatomy and Embryology. 1st Edition. LWW. 234 p. ISBN-10: 1605473154, ISBN-13: 978-1605473154. Precīzs embrioloģisko struktūru attainojums; nav atkārtota izdevuma.

10.

Schoenwolf Gary C. 2007. Atlas of Descriptive Embryology. 7th Edition. Pearson. 300 p. ISBN-10: 0131585606, ISBN-13: 978-0131585607. Precīzs embrioloģisko struktūru attainojums; nav atkārtota izdevuma.