Abdominal Organ Transplantation II

The student independently acquires theoretical knowledge, prepares and conducts seminars on transplantology issues: -organization of transplantation service: legislation and ethical aspects in transplantation; principles of organ allocation; non-immunological bases of determining the donor/recipient pair (organ sizes, body weight of the recipient, age); transplant combinations and their role in improving transplant results, organ exchange; immunological criteria for transplantation; immunological bases of determining the donor / recipient pair (ABO match, HLA match, cross-match), rejection mechanisms of transplanted organs; -immunosuppression: basic groups of immunosuppressants, mechanism of action, pharmacokinetics; use of immunosuppressive drugs, level monitoring, complications, side effects; preservation of organs and tissues, ischemia, cell biochemistry and physiology during ischemia and preservation, preservation with hypothermia, preservation solutions of organs and tissues, properties of preservation of various organs, complications of reperfusion in cases of preservation of organs; taking kidney, part of liver, part of pancreas for transplantation from living donors; -kidney transplantation: indications and contraindications, examination of patients and preparation for transplantation, kidney transplantation surgery, features of anesthetic provision, complications of reperfusion and possible prevention, protocols of immunosuppressive therapy, early postoperative complications, immediate and delayed function of the graft and patient management tactics; kidney transplant rejection, its diagnosis and treatment; the early postoperative period, complications of infections and their treatment and prevention, radiological examination of patients with transplants; kidney transplant pathologies, puncture biopsy in the diagnosis of dysfunctions; re-transplantation – peculiarities of preoperative preparation and management of the postoperative period; tactics of management and preparation of hypersensitized patients, choice of immunosuppression and its peculiarities; kidney transplantation in children; -pancreas transplantation: indications and contraindications, transplantation from living and deceased donors, surgical technique, early and late postoperative complications, immunosuppression, retransplantation. -liver transplantation: indications and contraindications, transplantation from living and deceased donors, surgical technique, early and late postoperative complications, immunosuppression, retransplantation. -small intestine transplantation: patient selection, donor selection, technique, immunosuppression technique; basics of obtaining and transplanting other organs – heart, lung, uterus, vascularized composite tissue, etc. transplantation: indications, selection of patients, transplantation technique, postoperative period; outpatient follow-up of post-transplantation patients, complications of the late period, quality of life of patients; xenotransplantation and the use of new technologies: opportunities and perspectives, limitations, immunological and non-immunological problems. Must learn practical skills in transplanting abdominal organs from living and deceased donors. Must be able to provide qualified transplantological assistance to organ transplant recipients, providing pre-transplantation preparation, operative assistance and post-transplantation treatment.

Teacher evaluates the practical skills in a 10-point system, recording it in the resident's book. The test of theoretical knowledge is conducted in writing and is graded in a 10-point system.