Veidlapa Nr. M-3 (8)
Study Course Description

Kidney Transplantation

Main Study Course Information

Course Code
RBN_010
Branch of Science
Anatomy; Clinical medicine
ECTS
19.00
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To ensure the acquisition and improvement of theoretical knowledge and practical skills, in accordance with laws and regulations of the Republic of Latvia, in order to prepare the doctor for certification in the specialty of paediatric nephrologist.

Learning Outcomes

Knowledge

1.Able to demonstrate knowledge of kidney transplantation procedures, types, indications; preparation of donors and recipients, transplantation therapy, diagnosis and treatment of acute and chronic complications.

Skills

1.To prepare CKD patient for transplantation, evaluate transplant function and determine the tactics of immunosuppressive therapy, diagnose and prevent acute and chronic complications.

Competences

1.Using knowledge of kidney pathophysiology, transplantation immunology, biological mechanisms of immune rejection, transplantation procedure, as well as treatment, rehabilitation and prevention of complications of transplant patients resulting from this knowledge.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Studies literature, prepares for seminars.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
At the end of the cycle - report on work during the rotation cycle; testing of theoretical knowledge in the form of questions.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
-
-

Topics

Transplantation immunology. Biological mechanism of immune rejection.
  1. Seminar

Modality
Location
-
-

Topics

Indications and contraindications for living related donor and deceased-donor kidney transplantation. Preemptive transplantation.
  1. Seminar

Modality
Location
-
-

Topics

Examination and preparation of the recipient.
  1. Seminar

Modality
Location
-
-

Topics

Donor (living and deceased) examination algorithm. Principles of organ procurement and transportation
  1. Seminar

Modality
Location
-
-

Topics

Transplantation procedure. Technical issues in children.
  1. Seminar

Modality
Location
-
-

Topics

Early and late complications of transplantation. Transplant thrombosis. Urological complications. Transplant dysfunction, delayed transplant function.
  1. Seminar

Modality
Location
-
-

Topics

Types of immune rejection - hyperacute, acute, late, chronic. Chronic transplant nephropathy. Diagnosis, tactics, therapy.
  1. Seminar

Modality
Location
-
-

Topics

Relapse of the underlying disease in the transplant (FSGS, HUS, membranoproliferative glomerulonephritis, oxalosis, metabolic diseases, IgA nephropathy).
  1. Seminar

Modality
Location
-
-

Topics

Immunosuppression in kidney transplantation: induction therapy, maintenance therapy, treatment of immune rejection. Combinations of immunosuppressive therapy.
  1. Seminar

Modality
Location
-
-

Topics

Kidney transplant complications associated with immunosuppressive therapy: urinary tract infection, CMV, herpes infection, EBV infection, BK virus infection, Pneumocystis infection, fungal infections; leukopenia, anaemia, thrombocytopenia; tumours.
  1. Seminar

Modality
Location
-
-

Topics

Psychosocial aspects of transplantation.
  1. Seminar

Modality
Location
-
-

Topics

Rehabilitation.
Total ECTS (Creditpoints):
19.00
Number of Residency Seminars:
12
Length (weeks):
14
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Kidney Transplantation - Principles and Practice. 8th Edition. Tuart Knechtle, Lorna Marson, Peter Morris. Elsvier, August 31, 2019

2.

Oxford Textbook of Clinical Nephrology, 3 sējumos. Edited by: Neil N. Turner, Norbert Lameire, et.al. 2018, Oxford University Press.

3.

National Kidney Foundation Primer on Kidney Diseases. 7th Edition. Scott Gilbert, Daniel Weiner. Elsvier, September 11, 2017

Other Information Sources

1.

UpToDate in Medicine — CD-ROM database, BDR Inc., Boston.

2.

Žurnāli ( Kidney International, Nephrology Dialysis Transplantation, Journal of American Society of Nephrology)