Kidney Transplantation
Study Course Implementer
Residency Speciality
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About Study Course
Objective
Learning Outcomes
Knowledge
1.Able to demonstrate knowledge of kidney transplantation procedures, types, indications; preparation of donors and recipients, transplantation therapy, diagnosis and treatment of acute and chronic complications.
Skills
1.To prepare CKD patient for transplantation, evaluate transplant function and determine the tactics of immunosuppressive therapy, diagnose and prevent acute and chronic complications.
Competences
1.Using knowledge of kidney pathophysiology, transplantation immunology, biological mechanisms of immune rejection, transplantation procedure, as well as treatment, rehabilitation and prevention of complications of transplant patients resulting from this knowledge.
Assessment
Individual work
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Title
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% from total grade
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Grade
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1.
Individual work |
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Studies literature, prepares for seminars.
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Examination
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Title
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% from total grade
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Grade
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1.
Examination |
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-
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At the end of the cycle - report on work during the rotation cycle; testing of theoretical knowledge in the form of questions.
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Study Course Theme Plan
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Seminar
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Modality
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Location
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Topics
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Transplantation immunology. Biological mechanism of immune rejection.
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Seminar
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Modality
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Location
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Topics
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Indications and contraindications for living related donor and deceased-donor kidney transplantation. Preemptive transplantation.
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Seminar
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Modality
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Location
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Topics
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Examination and preparation of the recipient.
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Seminar
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Modality
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Location
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Topics
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Donor (living and deceased) examination algorithm. Principles of organ procurement and transportation
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Seminar
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Modality
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Location
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Topics
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Transplantation procedure. Technical issues in children.
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Seminar
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Modality
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Location
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Topics
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Early and late complications of transplantation. Transplant thrombosis. Urological complications. Transplant dysfunction, delayed transplant function.
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Seminar
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Modality
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Location
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Topics
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Types of immune rejection - hyperacute, acute, late, chronic. Chronic transplant nephropathy. Diagnosis, tactics, therapy.
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Seminar
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Modality
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Location
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Topics
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Relapse of the underlying disease in the transplant (FSGS, HUS, membranoproliferative glomerulonephritis, oxalosis, metabolic diseases, IgA nephropathy).
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Seminar
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Modality
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Location
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Topics
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Immunosuppression in kidney transplantation: induction therapy, maintenance therapy, treatment of immune rejection. Combinations of immunosuppressive therapy.
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Seminar
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Modality
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Location
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Topics
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Kidney transplant complications associated with immunosuppressive therapy: urinary tract infection, CMV, herpes infection, EBV infection, BK virus infection, Pneumocystis infection, fungal infections; leukopenia, anaemia, thrombocytopenia; tumours.
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Seminar
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Modality
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Location
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Topics
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Psychosocial aspects of transplantation.
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Seminar
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Modality
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Location
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Topics
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Rehabilitation.
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Bibliography
Required Reading
Kidney Transplantation - Principles and Practice. 8th Edition. Tuart Knechtle, Lorna Marson, Peter Morris. Elsvier, August 31, 2019
Oxford Textbook of Clinical Nephrology, 3 sējumos. Edited by: Neil N. Turner, Norbert Lameire, et.al. 2018, Oxford University Press.
National Kidney Foundation Primer on Kidney Diseases. 7th Edition. Scott Gilbert, Daniel Weiner. Elsvier, September 11, 2017
Other Information Sources
UpToDate in Medicine — CD-ROM database, BDR Inc., Boston.
Žurnāli ( Kidney International, Nephrology Dialysis Transplantation, Journal of American Society of Nephrology)