Veidlapa Nr. M-3 (8)
Study Course Description
Transfusiology
Course Code
RTR_005
Branch of Science
Anaesthesiology and Resuscitation; Clinical medicine
ECTS
18.00
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Natālija Kanta
Residency Speciality
Speciality
Transfusiologist
Supervisor of Medical Speciality
Natālija Kanta
Contacts
-
About Study Course
Objective
To provide theoretical and practical skills according to the requirements of the profession, to prepare specialists for transfusiologists sertification in compliance with the Latvian legislation
Learning Outcomes
Knowledge
1.Preparation of blood components. Compatibility tests for blood transfusion. Transfusion of blood components in surgery, neonatology, urgent medicine. Consultation general medical practitioner and other medical staff on current transfusion practices.
Skills
1.Ability to prepare blood and blood components. Ability to do immunohematological examination and compatibility testing. Ability to consult general medical practitioner and other medical staff on current transfusion practices. Ability to transfuse blood components.Patient Blood Management.
Competences
1.Finishing the course the students will have the necessary competence to work at blood establishment/ hospital blood bank/ immunohaematological laboratory, they will have good knowledge in Transfusion Medicine and approved medical technologies, if necessary they will be able to consult general medical practicioners and other medical staff on current transfusion practices.
Assessment
Individual work
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Individual work |
-
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-
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|
Pedagogical work - preparation of lectures / presentations for donor education or transfusion practices. Participation in donor attraction and education (mass media, publications, etc.).
Completion of study course evaluation questionnaires.
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Examination
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Title
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% from total grade
|
Grade
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|---|---|---|
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1.
Examination |
-
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-
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|
A publication or presentation has been prepared.
There were speeches in TV or radio.
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Study Course Theme Plan
FULL-TIME
Part 1
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Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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EP directives, Cabinet of Ministers regulations and other normative documentation.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Hygiene and disinfection requirements for blood establishments.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
|
Quality system in the Blood Service. Hemovigilance.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
|
Specialized room
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Topics
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Donor attraction, promotion of donor movement. Donor selection. Donor information about blood and blood component donation process, donor's rights and obligations. Documentation and registration of donor's adverse events, notification procedure.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
|
Specialized room
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Topics
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Blood preparation. Requirements for labeling and identification of blood samples. Traceability, storage, transportation.
Preparation and modification of blood components. Preparation of cryoprecipitate.
Automatic apheresis procedure.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Selection and labeling of blood components. Storage, transportation, stock management of blood components. Irradiation of blood components.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Haematological and immunohematological testing of blood samples.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Serological and molecular testing (NAT) of viral markers. Risk of transmission of viral infectious diseases. Procedure for retrospective testing of donor blood samples.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Quality control of blood components.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
|
Specialized room
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Topics
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Immune system. Immunological aspects of transfusion therapy. Erythrocyte antigens. Antibodies. Mechanism of immune response. Antigen-antibody interaction. ABO system, genetics. Determination of ABO system blood groups. Clinical significance of subgroups of anti-A1 antibodies.
Aloimunization mechanism. Erythrocyte antigen systems. Special donor selection. Neonatal haemolytic disease: ABO, RH, etc. Prophylaxis with anti-D immunoglobulin.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Adverse reactions associated with blood components transfusions.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Quality assurance in laboratories. Requirements for acceptance and rejection of samples. Records and document management. Testing results reporting to donor.
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-
Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Types of blood components, indications, contraindications, advantages of use. Transfusion effectiveness criteria.
Plasma derivates, indications for ude. Adverse reactions.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Blood component transfusion medical technology. Patient blood management system
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Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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Principles of diagnosis and treatment of acute and chronic leukemia and myelodysplastic syndromes.
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Seminar
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Modality
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Location
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|---|---|---|
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-
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-
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Topics
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Treatment of hemophilia. Use of blood components in acute and chronic haematological diseases. Blood components therapy.
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Seminar
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Modality
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Location
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|---|---|---|
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-
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-
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Topics
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Principles of blood component transfusion in stem cell transplantation.
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Seminar
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Modality
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Location
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|---|---|---|
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-
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-
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Topics
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Anemia. Principles of therapy in various cases of anemia. Indications for transfusion of blood components in anemia.
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-
Seminar
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Modality
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Location
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|---|---|---|
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-
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-
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Topics
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Blood-borne infectious diseases (viral hepatitis, HIV, AIDS, CMV) and bacterial infections: etiology, pathogenesis, clinic, diagnosis, treatment.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Bacterial infections-etiology, pathogenesis, clinic, diagnosis, treatment.
Prions and chronic neurodegenerative diseases - etiology, pathogenesis, clinic, diagnosis, treatment
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Parasitic infections. Malaria. Toxoplasmosis.
Leishmaniasis.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Confirmatory testing of donor blood samples, interpretation of test results.
|
-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Organs and cells of the immune system. Cellular and humoral immunity, laboratory testing. Acquired and congenital immunodeficiency. Opportunistic infections.
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Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Neonatal alloimmune thrombocytopenia. Neonatal hemorrhagic syndrome and its differential diagnosis. Tactics of transfusion care in newborns in case of various pathologies. Guidelines for the use of blood components in neonates.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Evaluation of laboratory and clinical parameters, tactics, selection of blood components. Transfusion therapy in surgery.
|
-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Transfusion therapy in cardiac surgery. Artificial circulation.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Selection and use of antiplatelet agents, anticoagulants and fibrinolytics drugs.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Emergency medical care in various clinical situations. Transfusion tactics in patients with major bleeding in DIC.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
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-
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Topics
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Types of shock, diagnosis, principles of treatment. Politrauma treatment algorithm.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
|
-
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Topics
|
Crystalloids and colloids indications for use and advantages. Selection of blood components for transfusion.
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-
Seminar
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Modality
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Location
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|---|---|---|
|
-
|
-
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Topics
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Burn disease, sepsis. Tactics in case of burn shock. Transfusion therapy in patients with burn shock.
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-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
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Topics
|
Therapeutic apheresis, indications.
|
Total ECTS (Creditpoints):
18.00
Number of Residency Seminars:
32
Length (weeks):
48
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Ņemceva, G., Sisene, I., Šteinerte, A. Praktiskā transfuzioloģija. Rīga: Medicīnas apgāds; 2009. -126 lpp.
2.
Maitta, Robert W. Immunologic Concepts in Transfusion medicine. 2020, pp.-367
3.
Canellos, George, P., Bunn, H. Franklin. Hematology/Oncology Clinics, Transfusion Medicine. 2019.
4.
Vossoughi, Sarah R., Brie, A. Clinics in Laboratory Medicine, Topics in pediatric transfusion medicine. Stotler, 2021.
5.
ABC of Transfusion. Contreras, M., ed., Chichester; Wiley-Blackwell; 2009. pp -81
6.
Daniels, G., Bromilow, I. Essential Guide to Blood Groups. Oxford: Blackwell; 2009. pp -97
7.
Quinley, E. D. Immunohematology. Principles & Practice. 3rd ed. Lippincot Williams&Wilkins, 2011. pp -411
8.
Guide to the preparation, use and quality assurance of blood components. 20th ed. Council of Europe; 2020. pp -436
9.
Murphy, M. F., Pamphilon, D. H. Practical transfusion medicine. 3rd ed. Oxford: Wiley-Blackwell; 2009. pp -366
10.
Principles and Practice of Infectious Diseases. 6th ed. N.Y.: Mandell, Douglas & Bennett, 2007.
11.
Handbook on Haematopoietic Stem cell Transplantation. Ed. by Apperley, J., Carreras, E., Gluckman, E., Gratwohl, A., Masszi, T. – Rev. ed. European School of Haematology, 2008.
12.
Wintrobe’s Clinical Hematology. Ed. by Greer, J. P., Foerrester, J., et al. 12th ed. Lippincott, William & Wilkins, 2009.
13.
Abbas, A. K., Lichtman, A. H., Baker, D. L. Basic Immunology: Functions and Disorders of the Immune System. 3rd updated ed. Saunders, 2010.
14.
Immunology and serology in Laboratory Medicine. 4th ed.,Turgeon, M. L. Mosby, 2008. pp -526
15.
Immunologic Concepts in Transfusion Medicine. edited by Robert W. Maitta, 2020
16.
Denise, M., Harmening, F. A. Modern blood banking&Transfusion Practices. 5th ed. Davis Company, pp -543
17.
Blood banking and transfusion practices, Paula R.Howard, Elsever, 2025
18.
Transfusion medicine and hemostasis, Beth H.Shaz, Elsever,2025
Additional Reading
1.
Engelfriet, C. P. Immunohaematology. Amsterdam: Sanquin, 2003.
2.
Rozentāle, B., Dzenis, J. Antimikrobiskās terapijas ceļvedis. Rīga: SIA Nacionālais medicīnas apgāds, 2004.
3.
Lejniece S. Klīniskā hematoloģija. Rīga: Medicīnas apgāds, 2020., latv.-439.lpp
4.
Hoffbrand, A. V., Catovsky, D., Tuddenham, E. Postgraduate Haematology. 5th ed. Oxford: Blackwell; 2005. pp -1073
5.
Transfusion therapy: clinical principles and practice. 2nd ed., Mintz, P. D., ed. Bethesda: AABB Press; 2005. pp -716
6.
Klein, Harvey G. Mollison`s blood transfusion in clinical medicine. 11th ed. Oxford: Blackwell; 2005. pp -891
7.
Mazjānis, I., Tirāns, E. Infekcijas slimības, Rokasgrāmata. 2. izd. Valmiera; 2006. -1008 lpp.
8.
Immunology. 7th ed. Eds.: Male, D., Brostoff, J., Roth, D. B., Roitt, I., Mosby, 2006.
9.
Vossoughi, Sarah R., Stotler, Brie A. Topics in pediatric transfusion medicine. 2021, pp-171
10.
Transfusion Medicine. Eds.: George P. Canellos, H. Franklin Bunn. 2019.
11.
Paula R.Howard, Blood Banking and Transfusion Practices, Fifth edition, Elsevier, 2019, 420 lpp.
12.
A.Lejnieka red., Kliniskā medicīna, trešā grāmata, Medicīnas apgāds, 2012, 537 lpp.
13.
Johns, Gockel-Blessing, Zundel, Denesiuk, Clinical Laboratory Blood banking and Transfusion Medicine, Principles and Practice, Pearson, 2015, 455 lpp
14.
Mark T. Friedman, Kamille A.West, Peyman Bizargity, Immunohematology and Transfusion Medicine , A case stude Approach, Springer, 2016, 180 lpp
15.
Marion E.Reid, Christine Lomas-Francis and Martin L.Olsson, The Blood group antigen, Third edition, 2012, 731 lpp.