Veidlapa Nr. M-3 (8)
Study Course Description
Laboratory Diagnostics
Course Code
REN_019
Branch of Science
Clinical medicine; Internal medicine
ECTS
6.00
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Vitolds Mackēvičs
Residency Speciality
Speciality
Endocrinologist
Supervisor of Medical Speciality
Vitolds Mackēvičs
Contacts
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About Study Course
Objective
To provide medical residents with theoretical knowledge and practical skills in the methods used in laboratory diagnostics and experimental research projects. Understanding the execution and interpretation of various experimental examinations and results, according to the standards of molecular biology, in order to prepare the doctor to purposefully read and understand published experimental and clinical studies.
Learning Outcomes
Knowledge
1.To theoretically and practically understand clinical and experimental laboratory investigations and related endocrine pathology.
Skills
1.To understand the operational principles of large laboratory analysers (nephelometry, turbidimetry, etc.). To learn to accurately interpret laboratory test results: blood count, biochemical indicators, coagulation and thrombosis indicators, hormonal indicators, urinalysis. To be able to evaluate various molecular biological examinations related to endocrine pathology. To theoretically understand the principles of conducting these experiments.
Competences
1.Ability to independently apply the acquired knowledge in the use of laboratory examination methods in case of endocrine diseases. Ability to navigate and interpret laboratory data from experimental and clinical studies published in the scientific literature.
Assessment
Individual work
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Title
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% from total grade
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Grade
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1.
Individual work |
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Endocrinology medical resident acquires knowledge and skills about various laboratory examinations used in research, diagnosis and evaluation of endocrine diseases. The medical resident participates in the application of various diagnostic and treatment methods, must attend planned seminars. To prepare clinical case presentations for seminars with emphasis on laboratory diagnostics. To get acquainted with the latest literature and prepare literature reviews. To understand the dynamics of laboratory diagnostics and control of endocrine diseases. Preparation for the examination test.
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Examination
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Examination |
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-
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2.
Examination |
-
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-
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The theoretical seminar material has been learned, the seminar test works have been successfully passed.
Correct selection and accurate interpretation of various laboratory indicators at the patient’s bedside.
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Study Course Theme Plan
FULL-TIME
Part 1
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Seminar
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Modality
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Location
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On site
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Specialized room
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Topics
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Methods for determining protein concentration and activity (biochemistry, spectrometry, immunoblot, ELISA - enzyme-linked immunosorbent assay) - theory, demonstrations.
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Seminar
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Modality
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Location
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On site
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Specialized room
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Topics
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Characterisation of receptor-ligand interaction in the study of the mechanism of action of medicinal substances (examples, radioligand binding experiments, tissue sections).
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Seminar
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Modality
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Location
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|---|---|---|
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On site
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Specialized room
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Topics
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In vitro studies: work in sterile conditions with cell cultures, isolated organ systems (heart, aorta) - theory, demonstrations.
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Seminar
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Modality
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Location
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On site
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Specialized room
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Topics
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Experimental laboratory animal models - theory, demonstrations.
a. CNS, toxicology
b. Cardiovascular system
c. Diabetes, metabolic models
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Total ECTS (Creditpoints):
6.00
Number of Residency Seminars:
4
Length (weeks):
4
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Tutorials in Clinical Chemistry. English edition, by Ibrahim A. Hashim, 2022
2.
Impacts of Medications on Male Fertility (Advances in Experimental Medicine and Biology, Band 1034). English edition, by Erma Z. Drobnis and Ajay K. Nangia, 2019
3.
Clinical Biochemistry: An Illustrated Colour Text. English edition, by Michael J. Murphy MA MD FRCP FRCPath, Rajeev Srivastava MS FRCS FRCPath, et al., 2018
4.
Endocrine Biomarkers: Clinicians and Clinical Chemists in Partnership (Clinical Aspects and Laboratory Determination). English edition, by Hossein Sadrzadeh and Gregory Kline, 2017
5.
Endocrine Pathology: Differential Diagnosis and Molecular Advances. English edition, by Ricardo V. Lloyd, 2016
Additional Reading
1.
Endocrine Pathology: Differential Diagnosis and Molecular Advances. English edition, by Ricardo V. Lloyd, 2010
2.
Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice/ English edition, by Douglas T. Carrell and C. Matthew Peterson, 2010