Veidlapa Nr. M-3 (8)
Study Course Description
Pharmaceutical Dosage Form Technology
Course Code
LFK_030
Branch of Science
Basic medicine; Technology of Drug Forms
ECTS
11.00
Target Audience
Pharmacy
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Olga Kiseļova
Structure Unit Manager
Baiba Mauriņa
Structural Unit
Department of Applied Pharmacy
Contacts
Riga, 16 Konsula Street, zftk@rsu.lv, +371 67061547
About Study Course
Objective
The objective of the study course is to provide an opportunity to learn the theoretical foundations of pharmaceutical dosage form preparation and the practical skills required for the preparation of different dosage forms in a pharmacy.
Preliminary Knowledge
Inorganic chemistry, organic chemistry, physical pharmacy, mathematics, plant and animal biology, pharmacognosy, microbiology, pharmaceutical chemistry.
Learning Outcomes
Knowledge
1.As a result of successfully completing the study course, the student: 1. Will have the knowledge of the theoretical basis of the preparation of pharmaceutical dosage forms. 2. Will be able to answer questions about the preparation of dosage forms in a pharmacy. 3. Will be able to explain and justify the order of addition of ingredients to each dosage form.
Skills
1.As a result of learning the study course, the student will be able to: 1. to use methods for the technology of pharmaceutical forms, for the manufacture of medicinal products in pharmacy conditions; 2. to prepare different pharmaceutical forms with sufficient speed and quality; 3. evaluate and, if necessary, correct the process of the preparation of pharmaceutical dosage forms (powders, solutions, suspensions, semi-solid dosage forms) acquired in the study course.
Competences
1.As a result of completing the study course, students will be able to prepare medicinal products according to individual formulae in the pharmacy.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
Test
|
|
Individual work – to write a report on the prescriptions prepared in each practical class and solve situational problems. To evaluate the overall quality of the study course, the student must complete the course evaluation questionnaire in the Student Portal. |
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Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
10 points
|
|
Successfully passed four theoretical test works for full-time students. An exam consisting of one written theoretical questions and two prescription formulas. |
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Study Course Theme Plan
FULL-TIME
Part 1
-
Lecture
|
Modality
|
Location
|
Contact hours
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|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Powders as a dosage form, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Powders as a dosage form, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Powders as a dosage form, characteristics and preparation thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of simple and compound powder formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of simple and compound powder formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of simple and compound powder formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of simple and compound powder formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Liquid dosage forms, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Liquid dosage forms, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Liquid dosage forms, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Liquid dosage forms, characteristics and preparation thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of aqueous and non-aqueous solutions for different formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of aqueous and non-aqueous solutions for different formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of aqueous and non-aqueous solutions for different formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of mixtures as a dosage form.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
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|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of mixtures as a dosage form.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different mixture formulae.
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Total ECTS (Creditpoints):
5.00
Contact hours:
50 Academic Hours
Final Examination:
Test (Semester)
Part 2
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of mixtures as a dosage form (continuation of the topic).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different mixture formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different mixture formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characterisation and preparation of drops as a dosage form.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different drops formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of suspensions as a dosage form.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of suspensions as a dosage form.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Characteristics and preparation of suspensions as a dosage form.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different suspension formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different suspension formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different suspension formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Ointments as a dosage form, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Ointments as a dosage form, characteristics and preparation thereof.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Ointments as a dosage form, characteristics and preparation thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointment formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointment formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointment formulae.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of different ointment formulae.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
Off site
|
E-Studies platform
|
2
|
Topics
|
Suppositories as a dosage form, characteristics and preparation thereof.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
4
|
Topics
|
Preparation of a suppository formulae.
|
Total ECTS (Creditpoints):
6.00
Contact hours:
62 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Bouwman-Boer, Y., Fenton-May, V. and Le Brun, P., eds. 2015. Practical Pharmaceutics: An International Guideline for the Preparations, Care and Use of Medicinal Products. 1st ed. Heidelberg: Springer International Publishing.Suitable for English stream
2.
Marriott, J. F., Wilson, K. A., Langley C. A. and Belcher, D. 2010. Pharmaceutical Compounding and Dispensing. 2nd ed. London: Pharmaceutical Press.Suitable for English stream
3.
Kiseļova, O. 2022. Ekstemporālo zāļu pieejamība Latvijas aptiekās: situācijas kvantitatīvs un kvalitatīvs novērtējums un nākotnes perspektīva. Rīga: RSU.
4.
Ministru Kabinets. 23.03.2005. Recepšu veidlapu izgatavošanas un uzglabāšanas, kā arī recepšu izrakstīšanas un uzglabāšanas noteikumi. MK noteikumi Nr. 175. Latvijas Vēstnesis. 48.
5.
Ministru Kabinets. 08.05.2006. Noteikumi par zāļu ražošanas un kontroles kārtību, par zāļu ražošanu atbildīgās amatpersonas kvalifikācijas prasībām un profesionālo pieredzi un kārtību, kādā zāļu ražošanas uzņēmumam izsniedz labas ražošanas prakses sertifikātu. MK noteikumi Nr. 304. Latvijas Vēstnesis. 70.
Additional Reading
1.
Kiselova, O., Maurina, B., Sidlovska, V. 2020. Analysis of extemporaneous prescriptions prescribed by dermatovenerologists in Latvia and comparison with standardized compounded preparation monographs of Germany and USA. Medicina. 56(1), 29.Suitable for English stream
2.
Kiselova, O., Maurina, B., Sidlovska, V., Zvejnieks, J. 2019. The extent of extemporaneous preparation and regulatory framework of extemporaneous compounding in Latvia. Medicina. 55(9), 531.Suitable for English stream
3.
Handbook of extemporaneous preparation: a guide to pharmaceutical compounding / edited by Mark Jackson, Andrew Lowey, on behalf of the NHS Pharmaceutical Quality Assurance Committee. London: Pharmaceutical Press. 2010, xvi, 464 p.Suitable for English stream
4.
Voigt, Rudolf. Voigt Pharmazeutische Technologie. Berlin/Wiesbaden, 2021. - 800 p.
5.
Bauer, Frömming, Führer. Pharmazeutische Technologie mit Einführung in Biopharmazie und Biotechnologie. 2022
6.
Sandell, Erik. Pharmaceutics. Swedish Pharmaceutical Press. Stockholm, 1983. - 242 p.Suitable for English stream