Veidlapa Nr. M-3 (8)
Study Course Description

Morphological, Histological Diagnosis of Haematological Diseases

Main Study Course Information

Course Code
RHE_053
Branch of Science
Clinical medicine
ECTS
13.00
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To ensure acquisition and improvement of theoretical knowledge and practical skills in morphological/histological diagnosis of haematological diseases in accordance with the requirements of the haematology specialty in order to prepare the doctor for certification in the haematology specialty.

Learning Outcomes

Knowledge

1.- Knows about the methods of histopathology, immunohistochemistry, and the role of morphological examinations in the diagnosis of haematological diseases; - Knows about the principles of morphological examination of bone marrow, lymph nodes and other tissues.

Skills

1.- Able to analyse histopathology, immunohistochemistry methods and morphological examinations.

Competences

1.Analysis of histopathology, immunohistochemistry methods and morphological examinations.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
1. Independently studies the literature related to the course topics; 2. Independently prepares for seminars; 3. Gets acquainted with and analyses medical documentation; 4. Completes medical documentation; 5. Independently follows the instructions of the certified specialist.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
Mandatory attendance of seminars (100%) and performance of practical work (100%) in each study course.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
-
-

Topics

Methods of histopathology, immunohistochemistry. The role of morphological examinations in the diagnosis of haematological diseases. Principles of morphological examination of bone marrow, lymph nodes and other tissues.
  1. Seminar

Modality
Location
-
-

Topics

Morphological diagnosis of acute leukaemias and myelodysplastic syndromes. Histological examination of the bone marrow.
  1. Seminar

Modality
Location
-
-

Topics

Myeloma, its morphological diagnosis.
  1. Seminar

Modality
Location
-
-

Topics

Hodgkin’s disease, histological classification, morphological diagnosis.
  1. Seminar

Modality
Location
-
-

Topics

Non-Hodgkin’s disease, histological classification, morphological diagnosis.
  1. Seminar

Modality
Location
-
-

Topics

Morphological diagnosis of chronic lymphocytic leukaemia, hairy cell leukaemia.
  1. Seminar

Modality
Location
-
-

Topics

Morphological diagnosis of chronic myeloproliferative neoplasms. Bone marrow examination according to the criteria defined by the World Health Organization.
  1. Seminar

Modality
Location
-
-

Topics

Morphological diagnosis of aplastic anaemia, pure red cell aplasia, other anaemias.
Total ECTS (Creditpoints):
13.00
Number of Residency Seminars:
8
Length (weeks):
9
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Swerdlow S.H., Campo E., Harris N.L., Jaffe E.S., Pileri S.A., Stein H., Thiele J. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. WHO Classification of Tumours, Revised 4th Edition, Volume 2, 2017.

2.

Foucar K., Chabot-Richards D., Czuchlewski D.R., Hunt Karner K., et.al. Diagnostic Pathology: Blood and Bone Marrow. 2nd Edition, 2017, Elsevier.

3.

Medeiros L.J., Miranda R.N. Diagnostic Pathology: Lymph Nodes and Extranodal lymphomas. 2nd Edition, 2017, Elsevier.

4.

Barbara J. Bain, David M. Clark, Bridget S. Wilkins. Bone Marrow Pathology. 5th Edition, 2019, Wileys.

5.

Eric Hsi. Hemathopathology. 3rd Edition, 2017, Elsevier.

6.

Faramarz Naeim, P. Nagesh Rao, Sophie Song, Ryan Phan. Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches. 2nd Edition, 2018, Elsevier.

7.

Arber D.A., Orazi A., Hasserjian R., et.al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 2016; 127:2391-2405.

8.

Emile J.F., Abla O., Fraitag S., et.al. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood 2016; 127:2672.

9.

S.Lejniece. Klīniskā hematoloģija. Medicīnas Apgāds, 2020.

10.

Klīnisko analīžu rokasgrāmata. E.Gulbja laboratorija. Izdevējs E.Gulbja laboratorija, 2019.

11.

Alla Rivkina. Plūsmas citometrijas metode hematoloģisko slimību diagnostikā. SIA Medicīnas apgāds, 2019