Morphological, Histological Diagnosis of Haematological Diseases
Study Course Implementer
Residency Speciality
-
About Study Course
Objective
Learning Outcomes
Knowledge
1.- Knows about the methods of histopathology, immunohistochemistry, and the role of morphological examinations in the diagnosis of haematological diseases; - Knows about the principles of morphological examination of bone marrow, lymph nodes and other tissues.
Skills
1.- Able to analyse histopathology, immunohistochemistry methods and morphological examinations.
Competences
1.Analysis of histopathology, immunohistochemistry methods and morphological examinations.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
1. Independently studies the literature related to the course topics;
2. Independently prepares for seminars;
3. Gets acquainted with and analyses medical documentation;
4. Completes medical documentation;
5. Independently follows the instructions of the certified specialist.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
Mandatory attendance of seminars (100%) and performance of practical work (100%) in each study course.
|
||
Study Course Theme Plan
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Methods of histopathology, immunohistochemistry. The role of morphological examinations in the diagnosis of haematological diseases. Principles of morphological examination of bone marrow, lymph nodes and other tissues.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Morphological diagnosis of acute leukaemias and myelodysplastic syndromes. Histological examination of the bone marrow.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Myeloma, its morphological diagnosis.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Hodgkin’s disease, histological classification, morphological diagnosis.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Non-Hodgkin’s disease, histological classification, morphological diagnosis.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Morphological diagnosis of chronic lymphocytic leukaemia, hairy cell leukaemia.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Morphological diagnosis of chronic myeloproliferative neoplasms. Bone marrow examination according to the criteria defined by the World Health Organization.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Morphological diagnosis of aplastic anaemia, pure red cell aplasia, other anaemias.
|
Bibliography
Required Reading
Swerdlow S.H., Campo E., Harris N.L., Jaffe E.S., Pileri S.A., Stein H., Thiele J. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. WHO Classification of Tumours, Revised 4th Edition, Volume 2, 2017.
Foucar K., Chabot-Richards D., Czuchlewski D.R., Hunt Karner K., et.al. Diagnostic Pathology: Blood and Bone Marrow. 2nd Edition, 2017, Elsevier.
Medeiros L.J., Miranda R.N. Diagnostic Pathology: Lymph Nodes and Extranodal lymphomas. 2nd Edition, 2017, Elsevier.
Barbara J. Bain, David M. Clark, Bridget S. Wilkins. Bone Marrow Pathology. 5th Edition, 2019, Wileys.
Eric Hsi. Hemathopathology. 3rd Edition, 2017, Elsevier.
Faramarz Naeim, P. Nagesh Rao, Sophie Song, Ryan Phan. Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches. 2nd Edition, 2018, Elsevier.
Arber D.A., Orazi A., Hasserjian R., et.al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 2016; 127:2391-2405.
Emile J.F., Abla O., Fraitag S., et.al. Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages. Blood 2016; 127:2672.
S.Lejniece. Klīniskā hematoloģija. Medicīnas Apgāds, 2020.
Klīnisko analīžu rokasgrāmata. E.Gulbja laboratorija. Izdevējs E.Gulbja laboratorija, 2019.
Alla Rivkina. Plūsmas citometrijas metode hematoloģisko slimību diagnostikā. SIA Medicīnas apgāds, 2019