Sport Biochemistry
Study Course Implementer
Riga, 3 Cigorinu Street, suuk@rsu.lv, +371 67611559
About Study Course
Objective
Preliminary Knowledge
Learning Outcomes
Knowledge
1.As a result of the study course, the student acquires theoretical knowledge of bioenergetic processes in the body - metabolism of carbohydrates, fats and proteins, and also knows the basic principles of biochemical regulation of metabolic processes.
Skills
1.The student will be able to apply the theoretical knowledge acquired in the study course practically by explaining the processes taking place in the body: • metabolism of carbohydrates, fats and proteins as a single system of transformations in obtaining energy; • the importance of carbohydrate catabolism (aerobic and anaerobic glycolysis) and anabolism (glycogenolysis, gluconeogenesis); • the importance of fats and lipids in metabolism; • the role of replaceable and irreplaceable amino acids in obtaining energy and in the synthesis of protein molecules. In the study course, basic analytical skills and the necessary minimum of biochemical terminology are learned.
Competences
1.The student will be able to independently judge the course of metabolism in the human body. The student will be able to integrate the acquired knowledge and skills in further studies and professional work.
Assessment
Individual work
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Title
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% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
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-
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Independent learning of theoretical topics using educational literature and other sources (scientific publications, books, media resources).
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Examination
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Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
1. Participation in practical lessons, understanding and solving problem situations. 2. Written mid-term tests, which are mandatory to pass the course. 3. Final exam (written, multiple-question exam), which shows 100% mastery of the course material.
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Study Course Theme Plan
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
|
Auditorium
|
2
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Topics
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Explanation of the concept of metabolism. Energy requirements for metabolic processes.
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-
Lecture
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Digestion of food. Scheme of nutrient catabolism. The role of enzymes, vitamins and hormones in metabolic processes. Characterization of macroergic compound (ATF) molecules.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Main dietary carbohydrates. Carbohydrate digestion. Characteristics and energetic effect of the glycolysis process. Features of aerobic and anaerobic glycolysis. Breakdown of glucose to carbon dioxide and water.
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-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Glycogen synthesis and breakdown in liver and muscle. Common metabolites of glucose and other nutrient molecules in the catabolism process.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Main sources of dietary fat. Production of fat and lipid molecules and their role in cell membrane structure.
|
-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Fat digestion. Hydrolysis of reserve fat (lipolysis). Energetic effect of fatty acid catabolism. The role of carnitine in fatty acid catabolism. Synthesis of ketone bodies in the body. Causes of their formation and possible use. Negative features of ketoacidosis.
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-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
|
Characterization of complete proteins. Structure of protein molecules. Protein digestion. Essential amino acids. Formation and use of the amino acid pool. Formation and importance of creatine phosphate in muscles. Creatinine.
|
-
Lecture
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Modality
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Location
|
Contact hours
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|---|---|---|
|
On site
|
Auditorium
|
2
|
Topics
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Muscle biochemistry. Energy sources for skeletal muscles depending on the degree of activity (load). Substrates of aerobic metabolism in muscles. Comparison of energy sources in different loads.
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-
Class/Seminar
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Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
The main elements of the metabolic process. Digestion of food.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Structure of carbohydrate molecules. Monosaccharide and polysaccharide molecules. Digestion of monosaccharide and polysaccharide molecules in the intestinal tract and cellular metabolism.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
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|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Laboratory work. Differences in the molecular structure of monosaccharides and polysaccharides. Digestion of monosaccharide and polysaccharide molecules in the intestinal tract.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Fat digestion in the intestinal tract. Structure of lipid molecules. The structure of the cell membrane.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Structure of protein molecules. Primary, secondary, tertiary and quaternary structures of protein molecules. Protein digestion in the intestinal tract.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Metabolism of nitrogen-containing molecules (nucleic acids, heme, etc.).
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Laboratory work. Analytical determination of metabolic products.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Laboratory
|
2
|
Topics
|
Energy sources in muscles under different loads.
|
Bibliography
Required Reading
Nelson, Cox, Lehninger, Cox, Michael M, & Lehninger, Albert L. (2017). Lehninger principles of biochemistry / David L. Nelson, Professor Emeritus of Biochemistry, University of Wisconsin-Madison, Michael M. Cox, Professor of Biochemistry, University of Wisconsin-Madison. (7th ed.).
Nokalna, Nokalns, Lapsa, Brasliņš, Nokalns, Māris, Lapsa, Aija, . . . (2018). Organiskā ķīmija ar ievirzi bioķīmijā : Metodiskais materiāls studentiem / sastādītāji: I. Nokalna, M. Nokalns; redaktore: Aija Lapsa. RSU, Cilvēka fizioloģijas un bioķīmijas katedra. (2. papildinātais izdevums. ed.).
Lieberman, M. (2018). Marks' Basic Medical Biochemistry : A clinical approach / Michael Lieberman, Allan Marks, Alisa Peet ; illustrations by Matthew Chansky. (5th ed, international ed.).
Additional Reading
David L. Nelson; Michael M. (2021). Lehninger Principles of Biochemistry. 8th ed.
Victor W. Rodwell, David A. Bender, Kathleen M. Botham, et.al. (2020). Harper's Illustrated Biochemistry. 31st ed.
PUB MED un citas datu bāzes