Veidlapa Nr. M-3 (8)
Study Course Description

Toxicology

Main Study Course Information

Course Code
AURK_057
Branch of Science
Anaesthesiology and Resuscitation; Clinical medicine
ECTS
2.00
Target Audience
Clinical Pharmacy
LQF
Level 7
Study Type And Form
Full-Time

Study Course Implementer

Course Supervisor
Structure Unit Manager
Structural Unit
Department of Anaesthesiology, Intensive Care and Clinical simulations
Contacts

Riga, Pilsoņu Street 13, VSIA P.Stradiņa KUS, Building 32, aurk@rsu.lv, +371 67069452

About Study Course

Objective

To provide knowledge on the acute exogenous intoxication epidemiology, toxicokinetics, toxicodynamics and characteristics of the specific and most urgent (more common poisoning causes and / or high toxicity grade), poisonous substances with recommended principles of treatment and, as well to teach students to act in acute, life-threatening toxicological situations before arrival emergency service.

Preliminary Knowledge

Knowledge in biology, physiology, pathology and pharmacy courses completed.

Learning Outcomes

Knowledge

1.During the study course the students will complement the knowledge of clinical toxicology - toxicologically the most pressing substances, their toxicities, and treatment options.

Skills

1.The student will be able to: To assess the seriousness of the health condition of the poisoned person.

Competences

1.Students will be able to use the acquired competencies on the risk factors of acute exogenous intoxication, epidemiology, the amount of immediate medical care for an acute toxicological patient, linking it to the specific clinical situation.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Preparing presentations using the recommended literature and Internet sources, following evaluation and analysis in practical lessons. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
Test (multi-answer test and oral questions on the course topic). Evaluation criteria in the theoretical multi-answer test: more than 75% of correct answers.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
2

Topics

Clinical toxicology and its place in the medical field, toxicological epidemiology.
  1. Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
2

Topics

Toxicokinetics. Toxin absorption and elimination. Elimination of toxins and its promotion. Antidotes
  1. Lecture

Modality
Location
Contact hours
On site
Auditorium
2

Topics

General basic principles of acute intoxication treatment. Antidotes.
  1. Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
2

Topics

Toxic liver damage. Toxicity of household chemicals.
  1. Lecture

Modality
Location
Contact hours
Off site
E-Studies platform
2

Topics

Toxicological risks for women and pregnant women. Addictive substances.
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxicology of specific substances - ethanol and alcohol surrogates, benzodiazepines, neuroleptics, antidepressants
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxicology of addictive substances - opioids, cocaine, amphetamines
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxicology of specific substances - cardiovascular drugs
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxicology of specific substances - carbon monoxide, cyanides, hydrocarbons
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxicology of specific substances - non-steroidal anti-inflammatory drugs, paracetamol, aspirin
  1. Class/Seminar

Modality
Location
Contact hours
On site
Auditorium
2

Topics

Toxinology - insect and snake bites
Total ECTS (Creditpoints):
2.00
Contact hours:
22 Academic Hours
Final Examination:
Exam

Bibliography

Required Reading

1.

Klīniskā anestezioloģija un intensīvā terapija. Induļa Vanaga un Antoņinas Sondores redakcijā. Nacionālais Apgāds, 2017.

Additional Reading

1.

Derek Waller. Clinical Pharmacology and Poisoning. Elsevier, 2016

2.

Lindsay Murray. Toxicology Handbook. 3rd Edition, Elsevier Australia, 2022

Other Information Sources

1.

TOXNET Databases

2.

Agency for Toxic Substances and Disease Registry