Veidlapa Nr. M-3 (8)
Study Course Description

Diagnostics of Internal Diseases

Main Study Course Information

Course Code
RLA_013
Branch of Science
Clinical medicine; Medicinal Biochemistry
ECTS
12.00
Target Audience
Medicine
LQF
Level 8

Study Course Implementer

Course Supervisor

Residency Speciality

Speciality
Supervisor of Medical Speciality
Contacts

-

About Study Course

Objective

To prepare laboratory doctors capable of purposefully using laboratory testing methods for diagnostics of cardiovascular, renal, pulmonary, endocrinological, rheumatic, hepatic and other diseases. To understand the link between diagnostics, differential diagnostics of different diseases and laboratory tests. To master theoretical knowledge and practical skills. To apply examination algorithms and to interpret the results.

Learning Outcomes

Knowledge

1.- to evaluate advantages of different groups of diagnostic methods; - to describe criteria of selection of laboratory tests in case of different diseases; - to evaluate laboratory examination methods of blood-clotting disorders; - to characterise diagnostics and differential diagnostics of jaundice; - to evaluate clinical significance of inflammation markers; - to characterise laboratory diagnostics of renal, pulmonary, endocrinological diseases; - to know reference values of laboratory tests characterising the functional status of organs and factors that affect them.

Skills

1.- to perform biochemical, haematological and immunochemical examinations to diagnose different diseases; - to evaluate coagulation profile indicators; - to evaluate biochemical, haematological and immunochemical examination data; - to determine protein fractures using different examination methods; - to perform and evaluate microscopic examinations in case of different diseases.

Competences

1.To perform examinations of human biological material for diagnostics of different diseases. To use modern technologies and methods, diagnostic criteria and examination algorithms for diagnostics and differential diagnostics of diseases. To interpret results and to recommend further examination activity to clinicians.

Assessment

Individual work

Title
% from total grade
Grade
1.

Individual work

-
-
Preparation of a presentation about the use of laboratory tests in diagnostics of cardiovascular diseases. In-depth research: liver cell damage markers.

Examination

Title
% from total grade
Grade
1.

Examination

-
-
2.

Examination

-
-
Assessment of knowledge – written answers to questions at the end of the study course.

Study Course Theme Plan

FULL-TIME
Part 1
  1. Seminar

Modality
Location
-
-

Topics

Laboratory diagnostics of kidney diseases
  1. Seminar

Modality
Location
-
-

Topics

Laboratory diagnostics of atherosclerosis and ischemic disease
  1. Seminar

Modality
Location
-
-

Topics

Jaundice diagnostics and differential diagnostics
  1. Seminar

Modality
Location
-
-

Topics

Markers of inflammation and their clinical significance
  1. Seminar

Modality
Location
-
-

Topics

Laboratory diagnostics of endocrinological diseases
  1. Seminar

Modality
Location
-
-

Topics

Coagulation disorders, their clinical significance and laboratory examination methods
  1. Seminar

Modality
Location
-
-

Topics

Laboratory diagnostics of lung diseases
  1. Seminar

Modality
Location
-
-

Topics

Hospital infections
Total ECTS (Creditpoints):
12.00
Number of Residency Seminars:
8
Length (weeks):
10
Final Examination:
Residency exam (Theory and practice)

Bibliography

Required Reading

1.

Henry's Clinical Diagnosis and Management. by Laboratory Methods, 2021

2.

Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th Edition, 2014

3.

Mosby's Diagnostic and Laboratory Test Reference. 13th Edition, Ed: Kathleen Deska Pagana, Timothy J. Pagana, Theresa N. Pagana. 2016

4.

Preanalytical Phase Errors: Experience of a Central Laboratory Monitoring. Editor: Alexander Muacevic and John R Adler; e7335. Published online 2020 Mar 20. doi: 10.7759/cureus.7335

5.

Clinical Microbiology Procedures Handbook. Published by American Society for Microbiology. United States, 2016

6.

Oxford Handbook of Clinical and Laboratory Investigation. Edited by Drew Provan. Oxford University Press, 2018

Additional Reading

1.

Fred F. Ferri. Ferri's Best Test. A Practical Guide to Clinical Laboratory Medicine and Diagnostic Imaging. 3rd Edition, 2019

2.

A Guide to Laboratory Investigations. 7th Edition, Ed by Michael F. McGhee, Caroline A. Saxelby, Niall McKay. 2021, CRC Press, 153 Pages

3.

Diagnostic Testing for Enteric Pathogens, An Issue of Clinics in Laboratory Medicine. 1st Edition. Editor: Alexander McAdam, 2015, Volume 35-2.

4.

Laboratory Management, An Issue of Clinics in Laboratory Medicine.1st Edition, Editors: Ronald Weiss, Richard Friedberg. 2007, Volume 27-4.

Other Information Sources

1.

Practical Laboratory Medicine, Journal. Co Editors-in-Chief: William Clarke, Mike J. Hallworth

2.

The Journal of Laboratory and Clinical Medicine. The Official Publication of the Central Society for Clinical Research

3.

Clinical Chemistry and Laboratory Medicine (CCLM). Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Editor-in-Chief: Plebani, Mario