Veidlapa Nr. M-3 (8)
Study Course Description
Morphology (Histopathology)
Course Code
RLA_032
Branch of Science
Clinical medicine; Histology and Cytology
ECTS
6.00
Target Audience
Medicine
LQF
Level 8
Study Course Implementer
Course Supervisor
Jeļena Storoženko
Residency Speciality
Speciality
Laboratory doctor
Supervisor of Medical Speciality
Jeļena Storoženko
Contacts
-
About Study Course
Objective
To prepare laboratory doctors capable of performing morphological examination methods and using them for diagnostic purposes for diagnostics and differential diagnostics of different diseases. To use modern equipment to perform morphological examinations. To master theoretical knowledge and practical skills to orientate oneself in the range of examinations and to select the type of examinations according to the patient’s pathology and physiological properties. To make morphological descriptions of preparations and their interpretation. To apply examination algorithms.
Learning Outcomes
Knowledge
1.- to describe morphological examination methods; - to evaluate possibilities of using different morphological examination methods; - to describe principles of electron microscopy; - to characterise pathological changes in different tissues; - to evaluate most common errors in the interpretation of results.
Skills
1.- to perform routine fixation and paraffin embedding of different tissues; - to prepare tissue sections and stained preparations for routine morphological examination; - to evaluate preparations stained in daily work routine; - to perform microscoping methods for specifically hard tissues and implants; - to prepare and analyse immunohistochemical preparations in optical and fluorescence microscopes.
Competences
1.To perform morphological examinations of human tissues for diagnostics of different diseases. To select tissue staining and microscoping methods, to analyse the quality of prepared preparations. To use histopathological analyses in medical laboratory practice and differential diagnostics of diseases. To interpret results and to recommend further examination activity to clinicians.
Assessment
Individual work
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Individual work |
-
|
-
|
|
Preparation of a presentation about principles of operation, advantages and disadvantages of immunohistochemical methods, most common error in the interpretation of methods.
In-depth research: immune electron microscopy and use of its latest achievements in practical medicine.
|
||
Examination
|
Title
|
% from total grade
|
Grade
|
|---|---|---|
|
1.
Examination |
-
|
-
|
|
2.
Examination |
-
|
-
|
|
Testing of theoretical knowledge – defence of a research paper.
|
||
Study Course Theme Plan
FULL-TIME
Part 1
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Basics of histochemical methods and light microscopy
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Immunohistochemistry: methods, their essence, the positive and negative of each method, the most common mistakes.
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Basic principles of histopathological examination of biopsy material
|
-
Seminar
|
Modality
|
Location
|
|
|---|---|---|
|
-
|
-
|
Topics
|
Basic principles of histopathological examination of surgical material
|
Total ECTS (Creditpoints):
6.00
Number of Residency Seminars:
4
Length (weeks):
4
Final Examination:
Residency exam (Theory and practice)
Bibliography
Required Reading
1.
Histology: A Text and Atlas, with Correlated Cell and Molecular Biology. 6th Edition, Ed: Michael H. Ross, Wojciech Pawlina. 2016
2.
Mills, Stacey. Histology for Pathologists. 5th Edition, 2018
3.
Histology and Cell Biology: An Introduction to Pathology. 4th Edition, 2015
4.
James S. Lowe, Peter G. Anderson. Stevens & Lowe's Human Histology. 4th Edition, 2015
5.
Fred F. Ferri. Ferri's Best Test. A Practical Guide to Clinical Laboratory Medicine and Diagnostic Imaging. 3rd Edition, 2016
Additional Reading
1.
Kathleen Deska Pagana & Timothy J. Pagana & Thresa N. Pagana. Blood Cells. A Practical Guide, 4th Edition, Ed: Barbara I. Bain. Blackwell Pablishing, 2016
2.
Karin VanMeter, Robert Hubert. Study Guide for Gould's Pathophysiology for the Health Professions. 5th Edition, 2013
3.
Jessica M. Comstock. Diagnostic Pathology: Fetal Histology. 1st Edition, 2014
4.
Textbook of Histology and Practical guide, 2nd Edition
5.
David J. Dabbs. Diagnostic Immunohistochemistry. Theranostic and Genomic Applications. 5th Edition, 2017. eBook ISBN: 9780323551601
6.
S. N. Gallagher, E. A. Wiley, John Wiley. Current Protocols Essential Laboratory Techniques. California, 2008
7.
Ivan Damjanov. Atlas of Histopathology. 2012
Other Information Sources
1.
Journal Histopathology. Edited By: Daniel M Berney. 2020, Journal Citation Reports (Clarivate Analytics): 81/195 (Cell Biology)18/77 (Pathology)
4.
Histology ang histopathology. Journal
5.
Virchows Archiv Journal