Veidlapa Nr. M-3 (8)
Study Course Description
Microbiology, Immunology, Virology
Course Code
BUMK_077
Branch of Science
Clinical medicine; Microbiology and Virology
ECTS
8.00
Target Audience
Life Science; Medicine
LQF
Level 7
Study Type And Form
Full-Time
Study Course Implementer
Course Supervisor
Aigars Reinis
Structure Unit Manager
Juta Kroiča
Structural Unit
Department of Biology and Microbiology
Contacts
Riga, Dzirciema street 16, bmk@rsu.lv, +371 67061584
About Study Course
Objective
To acquire knowledge of the distribution, classification principles, morphology, pathogenic properties of micro-organisms, fungi and viruses and their interaction with the human body.
Preliminary Knowledge
Biology, anatomy, histology, physiology.
Learning Outcomes
Knowledge
1.After completing the study course, students will be able to describe common micro-organisms, viruses, fungi and prions, their distribution in the environment, their pathogenicity and their role in the development of infectious diseases and their interaction with the macro-organism. Students will be able to describe the immune system, its main mechanisms and its theoretical role in the destruction and neutralisation of infectious agents.
Skills
1.Students will be able to examine clinical material containing bacteria, to identify and isolate a pure culture of micro-organisms, to diagnose it, to define the sensitivity of the isolated pure culture to antibiotics in order to assess the sensitivity of the identified micro-organisms to antibiotics. Will acquire skills in the assessment of the pathogenesis of infectious diseases.
Competences
1.Combining theoretical knowledge with practical skills, students will be able to apply this knowledge in a single integrative understanding of the role of bacterial and viral pathogenicity factors in disease aetiology, to relate them to the mechanisms of pathogenesis and interactions with host immune mechanisms.
Assessment
Individual work
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Individual work |
-
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-
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Students will prepare presentations about the immune response, prevention of specific infectious diseases, current diagnostic methods and common causative agents of infectious diseases.
In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
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Examination
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Title
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% from total grade
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Grade
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|---|---|---|
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1.
Examination |
-
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-
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Protocol of practical work on microscopic examination of mixed culture; isolation of a pure culture from a mixed bacterial culture; interpretative reading and analysis of antibacterial sensitivity results obtained by disk diffusion method, E-test and VITEK2 analyzer
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2.
Examination |
-
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-
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Practical work for the determination of bacterial biofilms: reading and analysis of results, their reflection in the protocol.
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3.
Examination |
-
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-
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Work in groups, preparation of a protocol on virulence factors of microorganisms (adhesion, invasion, evasion, toxins, etc.)
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4.
Examination |
-
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-
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Presentation on an important infectious disease: analysis of etiology and pathogenesis, discussion of diagnostic principles and methods of prevention, including vaccination.
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5.
Examination |
-
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-
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At the end of the study course there is a cumulative examination consisting of the average mark of the semester's presentations and practical work. The student may choose to take a written examination consisting of essay-type questions instead of the cumulative examination.
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Study Course Theme Plan
FULL-TIME
Part 1
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Introduction into microbiology. Morphology of bacteria. Structure elements of microorganisms that are involved in pathogenesis of infectious diseases.
Physiology of microorganisms. Environmental and human body microbiota. Role of human microbiota, its interaction with host.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Introduction into microbiology. Morphology of bacteria. Structure elements of microorganisms that are involved in pathogenesis of infectious diseases.
Physiology of microorganisms. Environmental and human body microbiota. Role of human microbiota, its interaction with host.
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Factors affecting micro-organisms and their use in sterilisation and disinfection methods. Antibiotics. Bacterial resistance to antibiotics and their development.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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4
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Topics
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Work in microbiology laboratory. Preparation of specimens for microscopy and staining techniques.
Methods of cultivation of bacteria and fungi, methods used for isolation of pure cultures. Identification of pure culture. Detecting bacterial susceptibility to antibiotics. Disinfection and sterilisation.
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Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Seminar "Micro and macro-organism interaction”.
Pathogenicity factors of micro-organisms and their role in the infection process. Detection methods of pathogenicity factors. Bacterial biofilm formation and practical detection.
Routes of transmission of infectious disease.
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Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
|
Seminar "Micro and macro-organism interaction”.
Pathogenicity factors of micro-organisms and their role in the infection process. Detection methods of pathogenicity factors. Bacterial biofilm formation and practical detection.
Routes of transmission of infectious disease.
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-
Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Immunity. Non-specific resistance of the human body, its types and mechanisms.
Inflammation: mechanisms and inflammatory cytokines. Antigens and antibodies. Immunoglobulins.
Immunocompetent cells: formation and role in the immune response.
Types and mechanisms of immune response. Hypersensitivity.
Types and mechanisms of immune interactions with different groups of pathogenic agents.
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Lecture
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
|
Auditorium
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4
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Topics
|
Immunity. Non-specific resistance of the human body, its types and mechanisms.
Inflammation: mechanisms and inflammatory cytokines. Antigens and antibodies. Immunoglobulins.
Immunocompetent cells: formation and role in the immune response.
Types and mechanisms of immune response. Hypersensitivity.
Types and mechanisms of immune interactions with different groups of pathogenic agents.
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-
Lecture
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Immunity. Non-specific resistance of the human body, its types and mechanisms.
Inflammation: mechanisms and inflammatory cytokines. Antigens and antibodies. Immunoglobulins.
Immunocompetent cells: formation and role in the immune response.
Types and mechanisms of immune response. Hypersensitivity.
Types and mechanisms of immune interactions with different groups of pathogenic agents.
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-
Class/Seminar
|
Modality
|
Location
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Contact hours
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|---|---|---|
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On site
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Laboratory
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4
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Topics
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Serological diagnostic methods in infectious diseases. Molecular diagnostic methods in infectious diseases.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
|
4
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Topics
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Immunoprophylaxis of infectious diseases - its types and mechanisms.
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-
Class/Seminar
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Modality
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Location
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Contact hours
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|---|---|---|
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On site
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Auditorium
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4
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Topics
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Current bacterial and viral infections. Causative agents and pathogenesis of respiratory infections. Causative agents and pathogenesis of gastrointestinal infections. Hepatitis viruses, pathogenesis of hepatitis. Neurotropic viruses and prion infections and their pathogenesis. HIV/AIDS aetiology and pathogenesis.
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-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Current bacterial and viral infections. Causative agents and pathogenesis of respiratory infections. Causative agents and pathogenesis of gastrointestinal infections. Hepatitis viruses, pathogenesis of hepatitis. Neurotropic viruses and prion infections and their pathogenesis. HIV/AIDS aetiology and pathogenesis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Current bacterial and viral infections. Causative agents and pathogenesis of respiratory infections. Causative agents and pathogenesis of gastrointestinal infections. Hepatitis viruses, pathogenesis of hepatitis. Neurotropic viruses and prion infections and their pathogenesis. HIV/AIDS aetiology and pathogenesis.
|
-
Class/Seminar
|
Modality
|
Location
|
Contact hours
|
|---|---|---|
|
On site
|
Auditorium
|
4
|
Topics
|
Current bacterial and viral infections. Causative agents and pathogenesis of respiratory infections. Causative agents and pathogenesis of gastrointestinal infections. Hepatitis viruses, pathogenesis of hepatitis. Neurotropic viruses and prion infections and their pathogenesis. HIV/AIDS aetiology and pathogenesis.
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Total ECTS (Creditpoints):
8.00
Contact hours:
60 Academic Hours
Final Examination:
Exam (Written)
Bibliography
Required Reading
1.
Jawetz, Melnick, & Adelberg's. Medical Microbiology. 28th ed., 2019
2.
Warren Levinson, et al. McGraw Hill. Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 17th ed., 2022
3.
Ryan KJ. eds. Sherris & Ryan's Medical Microbiology. 8th ed. McGraw Hill, 2022.
Additional Reading
1.
Tsaras, Geoffrey, and Elie F. Berbari. "Prosthetic Joint Infections." Principles and Practice of Hospital Medicine. Eds.: Sylvia C. McKean, et al. McGraw Hill, 2017
2.
Chin-Hong P.V., & Guglielmo B. Health care–associated infections. Papadakis M.A., & McPhee S.J., & Rabow M.W., & McQuaid K.R. (Eds.). Current Medical Diagnosis & Treatment 2022. McGraw Hill.